Vargas is not in the lineup for Wednesday's contest in San Francisco.

Vargas started the previous two games at first base as the Diamondbacks scramble to fill the position following injuries to Pavin Smith (quadriceps) and Tyler Locklear (elbow), but Vargas will take a seat in Wednesday's series finale. Tim Tawa is handling first base and batting eighth as Arizona tries to avoid the sweep.

Wetherholt will return to the lineup at Triple-A Memphis on Wednesday after missing five games with general soreness, Katie Woo of The Athletic reports.

Woo writes that Wetherholt has been dealing with a "non-baseball ailment" but will be back in action at designated hitter Wednesday before returning to the field later this week. Wetherholt is slashing .309/.423/.519 with 16 home runs, 21 stolen bases and a 67:66 K:BB over 100 games this season between Double-A Springfield and Memphis. The top prospect is not expected to be promoted to the majors this month.

Kim isn't in the lineup for Tuesday's game against the Rockies.

After starting three straight games against right-handed starters, Kim will step out of the lineup Tuesday despite right-hander German Marquez taking the mound for Colorado. Miguel Rojas will get the nod at the keystone while batting ninth.

Castro will start in right field and bat seventh in Tuesday's game against Atlanta.

Castro will cover right field on the same day that Kyle Tucker was placed on the injured list due to a calf strain. While Tucker was out of the lineup for Monday's series opener, Seiya Suzuki drew the start in right field, and Castro played center field while Pete Crow-Armstrong occupied the designated-hitter spot. Crow-Armstrong should patrol center most days moving forward with Suzuki as the DH, which should open up right field for Castro on a near-everyday basis. Castro is batting just .164 in 24 games for the Cubs, but his playing time and fantasy value could get a temporary boost with Tucker on the IL.

Koss went 2-for-4 with two RBI, a run scored and a double in Monday's 11-5 win over the Diamondbacks.

Koss did most of his damage in the sixth inning, hitting a two-run double to right field before coming around to score. The 27-year-old infielder drew the start at second base after going four consecutive games without a plate appearance, delivering his 10th multi-hit performance of the season. He's slashing .258/.299/.361 with 20 RBI, 19 runs scored, three home runs and three stolen bases across 170 plate appearances in 67 games during the 2025 campaign.

Donovan (groin) will begin a rehab assignment with Double-A Springfield on Tuesday and could be activated from the 10-day injured list for this weekend's series in Milwaukee, Derrick Goold of the St. Louis Post-Dispatch reports.

Donovan took live batting practice Monday without issue and is slated to play six innings at second base in his first rehab game with Springfield on Tuesday. He will play at least one additional rehab game after that, and, if all goes well, might be back in the Cardinals lineup for their series opener Friday against the Brewers. Donovan has been sidelined since mid-August with a left groin strain.

Vargas started at first base and went 1-for-4 with a run scored in Monday's 11-5 loss to the Giants.

Vargas received the start at first base in the first game without the injured Tyler Locklear (elbow), who placed on the 10-day injured list Monday. The Diamondbacks are now without their top two first basemen, as Locklear joins Pavin Smith (quadriceps) on the IL. Arizona is expected to get by with a combination of Vargas, Tim Tawa and James McCann.

Marte went 3-for-5 with a run scored in Monday's 11-5 loss to the Giants.

Entering Monday, Marte had gone 0-for-13 across his previous four games, though he had four walks in that span. The second baseman was able to get his bat going again with his first three-hit game since he had four knocks Aug. 13 versus the Rangers. Marte is at a .287/.388/.520 slash line with 25 home runs, 64 RBI, 79 runs scored and four stolen bases across 111 contests this season.

Albies went 1-for-4 with a solo home run in Monday's 4-1 win over the Cubs.

Albies continued his red-hot stretch, blasting his third homer already in the month of September. The second baseman had a .616 OPS as of Aug. 13, but it appears that he was saving his best for last as the season nears a close. Across his last 24 outings, Albies is hitting .337 with 14 extra-base hits, 21 RBI, 18 runs scored and three stolen bases to raise his OPS to .682 for the campaign.

The Diamondbacks recalled Tawa (rib) from Triple-A Reno on Monday.

Tawa was placed on Reno's 7-day injured list Aug. 2 due to a fractured rib, but he was activated Wednesday and will now join the big club to contribute as a utility man. He'll join Arizona's 28-man active roster as a replacement for first baseman Tyler Locklear (elbow), who was placed on the 10-day IL.