Offensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Quarterback | S. DarnoldSam Darnold | D. LockDrew Lock | |
| Running Back | Z. CharbonnetZach Charbonnet | J. PriceJadarian Price | |
| Fullback | B. RussellBrady Russell | R. OuztsRobbie Ouzts | — |
| Wide Receiver | J. Smith-NjigbaJaxon Smith-Njigba | R. ShaheedRashid Shaheed | |
| Tight End | A. BarnerAJ Barner | E. SaubertEric Saubert | |
| Left Tackle | C. CrossCharles Cross | J. JonesJosh Jones | — |
| Left Guard | G. ZabelGrey Zabel | B. StephensBeau Stephens | |
| Center | J. SundellJalen Sundell | O. OluwatimiOlusegun Oluwatimi | — |
| Right Guard | A. BradfordAnthony Bradford | — | — |
| Right Tackle | A. LucasAbraham Lucas | J. JonesJosh Jones | — |
Defensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Left Defensive End | L. WilliamsLeonard Williams | M. MorrisMike Morris | — |
| Nose Tackle | B. Murphy IIByron Murphy II | B. PiliBrandon Pili | |
| Right Defensive End | J. ReedJarran Reed | R. MillsRylie Mills | — |
| Left Inside Linebacker | D. ThomasDrake Thomas | T. KnightTyrice Knight | |
| Right Inside Linebacker | E. JonesErnest Jones | P. O'ConnellPatrick O'Connell | — |
| Strongside Linebacker | U. NwosuUchenna Nwosu | D. HallDerick Hall | |
| Weakside Linebacker | D. LawrenceDeMarcus Lawrence | D. FowlerDante Fowler | — |
| Right Cornerback | J. JobeJosh Jobe | A. SmithAvery Smith | |
| Left Cornerback | D. WitherspoonDevon Witherspoon | N. PritchettNehemiah Pritchett | |
| Slot Cornerback | N. EmmanworiNick Emmanwori | — | — |
| Strong Safety | T. OkadaTy Okada | B. ClarkBud Clark | — |
| Free Safety | J. LoveJulian Love | R. Thomas IIRodney Thomas II | — |
Special Teams Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Punter | M. DicksonMichael Dickson | — | — |
| Kicker | J. MyersJason Myers | — | — |
| Long Snapper | C. StollChris Stoll | — | — |
| Holder | M. DicksonMichael Dickson | — | — |
| Punt Returner | R. ShaheedRashid Shaheed | T. HortonTory Horton | — |
| Kick Returner | R. ShaheedRashid Shaheed | G. HolaniGeorge Holani |