The White Sox designated Paez for assignment Wednesday.

Chicago will replace Paez on the 40-man roster and in the bullpen with right-hander Lucas Sims, who was called up from Triple-A Charlotte. Since Paez was a Rule 5 Draft selection over the winter, the White Sox will have to offer him back to the Red Sox if he goes unclaimed off waivers. The 22-year-old righty made relief appearances in three of the White Sox's first five games, allowing six earned runs on four hits and three walks while striking out two batters over three innings.

The Orioles placed Eflin (elbow) on the 15-day injured list Wednesday.

Eflin was lifted from his start Tuesday against the Rangers due to right elbow discomfort. He's set to undergo an MRI on Wednesday, at which point more will be known about how long he will be sidelined. Dean Kremer is likely to be called up from Triple-A Norfolk to take over Eflin's spot in the Baltimore rotation.

Gaddis (forearm) allowed one hit and struck out one over a scoreless inning for Triple-A Columbus on Tuesday.

Gaddis, who began a rehab assignment March 28, made his second appearance while with the Clippers. Cleveland manager Stephen Vogt told MLB.com that Gaddis needs to be built up to the point where the right-hander can reduce the time off between outings.

Fedde (0-1) took the loss Tuesday, giving up four runs (three earned) on six hits and a walk over five innings as the White Sox fell 9-2 to Miami. He struck out four.

The veteran right-hander tossed 50 of 80 pitches for strikes and held the Marlins off the board for three innings before things fell apart for him in the fourth. Fedde is hoping to recapture the form he showed in 2024 in his return to the White Sox, but about the only bright spot in Tuesday's performance is that he kept the ball in the yard after serving up 19 homers in 141 innings last season while bouncing between St. Louis, Atlanta and Milwaukee. Fedde is set to make his next start at home early next week against the Orioles.

Bibee (0-1) allowed one run on four hits and two walks while striking out four batters over four innings in a loss to the Dodgers on Tuesday.

Bibee had to be pulled from his first start last Thursday against Seattle due to a shoulder issue, but the injury didn't prove to be serious, and the right-hander was able to take his normal turn in the rotation Tuesday. He didn't pitch poorly, but he also wasn't efficient, needing 74 pitches to get through four frames. Bibee kept Los Angeles out of the scoring column until there were two outs in his final inning, but an Andy Pages single produced a run and was ultimately responsible for the hurler ending up with the loss. Bibee said after the game that he didn't have any issues with his shoulder, per Mason Horodyski of News 5 Cleveland, so he should be fine to make his next start, which lines up to come at home against Kansas City.

Gilbert (0-1) took the loss against the Yankees on Tuesday, allowing five runs on seven hits and three walks while striking out six batters over 5.1 innings.

Gilbert retired the first two batters he faced Tuesday, but three straight Yankees hits resulted in a pair of first-inning runs. The right-hander proceeded through the next four frames without falling further behind, but he imploded in the sixth, allowing four of the five batters he faced in that inning to reach base (on two doubles, a single and a walk) before being pulled. Overall, Gilbert threw just 54 of 95 pitches for strikes, and his three walks tied the most he recorded in any game last season. Gilbert did rack up 14 whiffs and now has 13 punchouts across 10.2 innings on the campaign, but he's also carrying a 6.75 ERA and 1.41 WHIP through two starts.

Fried (2-0) earned the win over Seattle on Tuesday, allowing three hits and issuing one walk while striking out six batters over seven scoreless innings.

Fried was sharp in his second start of the campaign, throwing 60 of 90 pitches for strikes and allowing a mere three hits (all singles). The star hurler has begun the regular season with 13.1 scoreless frames and a pair of quality starts, both of which resulted in victories. Fried will look to keep rolling in his next appearance, which tentatively lines up to take place at home against Miami this weekend.

DeGrom allowed three earned runs on six hits and no walks while striking out seven batters across 4.2 innings during Tuesday's 8-5 win over the Orioles. He did not factor into the decision.

DeGrom allowed just three batters to reach base through the first four innings, though one of them was Pete Alonso, who put the O's on the scoreboard with a leadoff homer in the fourth. A defensive miscue from Wyatt Langford in the fifth allowed Baltimore to tally two more runs against deGrom, causing the veteran righty to leave Tuesday's contest after 79 pitches with the score knotted at three apiece. He's lined up to make his next start at home against the Mariners and may be allowed to pitch a bit deeper into that contest, at which point he'll be further removed from the neck issues that delayed his debut.

Mize did not factor into the decision Tuesday, striking out nine and allowing one run on four hits and two walks over six innings during a 7-5 loss to the Diamondbacks.

Mize induced 15 swinging strikes on 93 pitches as he limited Arizona to a solo homer across six frames, but he lost out on the victory due to an eighth-inning collapse by the Detroit bullpen. The right-hander has never been a big punchout guy with a career 19.5 percent strikeout rate, but his splitter was in top form Tuesday, generating nine whiffs and six strikeouts. Mize lines up for a favorable road matchup against the Twins early next week.

McClanahan (0-1) took the loss Tuesday, allowing three runs (two earned) on two hits and three walks over 4.2 innings against Milwaukee. He struck out four.

The left-hander took an MLB mound Tuesday for the first time since August of 2023 after missing the past two seasons while recovering from Tommy John surgery and a subsequent nerve issue. McClanahan kept the Brewers off the board through four frames but was unable to escape the fifth, giving up three runs on two hits, two walks and an error. The 28-year-old threw 50 of 79 pitches for strikes and averaged 95.4 mph with his fastball, which is a tick slower than his 2023 velocity but is still an encouraging figure in his first start back, especially given that he topped out at 97.4 mph. A home matchup with the Cubs is likely on deck for McClanahan early next week.