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Deebo Samuel WR | SF
49ers' Deebo Samuel: Ruled out with hamstring injury
Samuel (hamstring) has been ruled out for the remainder of Sunday's game against the Seahawks, Ian Rapoport of NFL Network reports.
Samuel exited Sunday's contest in the third quarter. The wide receiver caught two of his three targets for 21 yards and rushed twice for four yards before being ruled out. Mike Evans, Brandin Cooks, Jacob Cowing and Jordan Watkins are the four active wideouts remaining for the 49ers in Sunday's game.
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Deebo Samuel WR | SF
49ers' Deebo Samuel: Out for remainder of Sunday's game
Samuel is out for the remainder of Sunday's game against the Seahawks due to a hamstring injury, Adam Schefter of ESPN reports.
Samuel went down in a heap during a rushing attempt late in the third quarter, ultimately suffering a hamstring injury and losing a fumble on the play. In his absence, Mike Evans will continue to operate as the team's undisputed No. 1 wide receiver. More information on Samuel's injury will likely be provided following Sunday's contest.
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Zay Flowers WR | BAL
Ravens' Zay Flowers: Active for SNF
Flowers (foot) is listed as active for Sunday's game in Atlanta.
Flowers endured practice restrictions during Week 5 prep, only this week he was dealing with a foot injury as opposed to the hamstring issue that had plagued him since the season opener. Despite Flowers entering the weekend as questionable to play, Adam Schefter of ESPN reported Sunday morning that the wide receiver was slated to suit up. Now that that's been confirmed, Flowers may have less sway in fantasy terms with QB Tyler Huntley directing the offense instead of Lamar Jackson (ankle), the latter of whom is inactive.
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Nico Collins WR | HOU
Texans' Nico Collins: Five grabs in Week 5 win
Collins caught five of seven targets for 56 yards in Sunday's 26-3 win over the Titans.
The Texans got right on both sides of the ball in their first win of the season, with Collins leading the team in targets and tying Jaylin Noel for the lead in receptions while Xavier Hutchinson topped them both in receiving yards. The trio will get some additional competition as soon as a Week 6 clash with Jacksonville after Houston traded for Marvin Harrison on Sunday, but Collins should remain the top option for C.J. Stroud as long as he remains healthy. Through three games this season, Collins has a 19-249-3 line on 25 targets.
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Rome Odunze WR | CHI
Bears' Rome Odunze: Three catches in Week 5 loss
Odunze brought in three of nine targets for 40 yards in the Bears' 31-7 loss to the Packers on Sunday. He also lost a fumble.
Odunze finished second in receiving yards with a team-high target total, and he endured an inefficient afternoon overall while working with Tyson Bagent as his quarterback for a second straight game. Odunze did take two of his receptions for first downs, and he extended his season-opening streak of recording at least one catch of 20-plus yards. The talented deep threat will look for a higher catch rate and better ball security in a Week 6 road matchup against the Falcons that could mark the return of Caleb Williams from his hamstring injury.
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Luther Burden III WR | CHI
Bears' Luther Burden: Leads pass catchers in loss
Burden secured four of six targets for 47 yards and rushed four times for two yards in the Bears' 31-7 loss to the Packers on Sunday.
Burden led the Bears in receptions and receiving yards, although he accomplished the feat during a highly unproductive day for Chicago's offense as a whole. Burden also had the Bears' longest reception of the day at 23 yards, and he's now drawn at least six targets in four consecutive games. The speedy second-year wideout has just one touchdown catch on the season, however, a matter he'll look to rectify in a Week 6 road matchup against the Falcons next Sunday.
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Tom Kennedy WR | DET
Lions' Tom Kennedy: Downgrades to out Sunday
Kennedy (knee) has been ruled out for the remainder of Sunday's game against the Cardinals.
Kennedy suffered a knee injury early in the second quarter and was evaluated for it. The injury is significant enough to keep the wide receiver out of the entire second half, leaving Amon-Ra St. Brown to take over return duties in his stead.
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Tee Higgins WR | CIN
Bengals' Tee Higgins: Two catches in Week 5 win
Higgins brought in two of four targets for 22 yards in the Bengals' 31-24 win over the Dolphins on Sunday.
Higgins was able to work through groin and neck injuries to suit up Sunday, but the veteran field-stretching receiver wasn't called on to do much on an afternoon when Joe Burrow threw for a season-low 192 yards. Nevertheless, Higgins seemingly made it through the game unscathed -- albeit with season-low totals across the board -- and he'll now have a Week 6 bye to further recover before a Week 7 road matchup against the Ravens on Sunday, Oct. 25.
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Tre Harris WR | LAC
Chargers' Tre' Harris: Dealing with hamstring injury
Harris (hamstring) is questionable to return to Sunday's contest against the Broncos.
Harris is dealing with an apparent hamstring injury, and his availability for the stretch run of Sunday's matchup is now up in the air. In his absence, Marquez Valdes-Scantling and Derius Davis will likely slot into more prominent roles on offense.
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Malik Nabers WR | NYG
Giants' Malik Nabers: Productive on career-high 20 targets
Nabers caught 11 of 20 targets for 121 yards and a touchdown in Sunday's 27-27 tie against the Commanders.
Nabers topped his previous career high of 18 targets, which came in Week 2 of his rookie 2024 season in what was also a road game against the Commanders. He caught a 17-yard touchdown with 1:43 remaining in regulation, and the ensuing PAT tied the game after the Giants had trailed by 14 earlier in the fourth quarter. Nabers also had a few near-misses, including two deep passes that hit his hands on the Giants' final drive of the first half, which ended with one of Dominic Zvada's three missed field goals in a game full of miscues from both teams. After posting just 96 scoreless yards through three games, Nabers has built momentum heading into a Week 6 home game against the Saints, with 233 receiving yards and two touchdown catches across his last two outings.