Darvish (3-4) took the loss Wednesday against the Mariners, allowing four runs on four hits and a walk over four innings. He struck out three.

Darvish was decent early, holding Seattle to a run on two hits through his first two innings. However, he'd stumble in the fourth, giving up a three-run homer to Eugenio Suarez that proved to be the difference in a 4-3 defeat. Darvish had gone five starts without a loss prior to Wednesday, posting a 3.00 ERA with an impressive 0.67 WHIP in that span (27 innings). Overall, his ERA sits at 5.66 with a 1.11 WHIP and 42:15 K:BB through 10 starts (47.2 innings) this season. Darvish is currently slated to face the Orioles at home in his next outing.

The Cubs recalled Assad from Triple-A Iowa on Wednesday, Taylor McGregor of Marquee Sports Network reports.

Chicago sent Assad back to the minors after he made a spot start this past Saturday, when he allowed one earned run and struck out four over six innings in a no-decision versus the Angels. Assad didn't have to wait long to return to the Cubs, as he'll slot back into the rotation as a replacement for Jameson Taillon (groin), who was placed on the 15-day injured list. Assad is in line to make his next start Saturday against the Rockies at Coors Field.

The Cubs placed Taillon on the 15-day injured list Wednesday due to a left groin strain, Taylor McGregor of Marquee Sports Network reports.

The injury forced him to make an early exit in his most recent start this past Sunday against the Angels, and after Taillon didn't bounce back as well as hoped in his bullpen session earlier this week, the Cubs have opted to send him back to the shelf for the second time this season. The right-hander had previously missed about two months due to a right calf strain prior to being activated Aug. 19 and making two starts for the Cubs before being shut down again with the groin issue. Javier Assad was recalled from Triple-A Iowa in a corresponding move and will replace Taillon in the rotation during this weekend's series in Colorado.

McLain will start at second base and bat ninth in Wednesday's game against the Dodgers.

McLain looked to have faded into a part-time role around the middle of the August following a prolonged rough patch at the plate, and though he has yet to get dialed back in, the Reds are giving him the chance to hit his way out of the slump. He'll stick in the lineup for a fourth straight game, though he'll need to heat up before he moves out of a bottom-third spot.

Ritter is out of the lineup for Wednesday's game against the Astros.

Though Ritter saw his 10-game hitting streak come to an end in Tuesday's 6-1 win, he remained productive from the bottom of the lineup by reaching base twice and coming around to score on both occasions. Orlando Arcia will fill in for Ritter at the keystone in Wednesday's contest.

Moniak is out of the lineup for Wednesday's game against the Astros.

With lefty Framber Valdez on the hill for Houston, the left-handed-hitting Moniak will exit the starting nine Wednesday, after he went 2-for-4 with a double, a stolen base, three RBI and a run in the Rockies' 6-1 win in Tuesday's series opener. He'll give up his spot in the lineup to Kyle Farmer, who will get the start at designated hitter and will bat eighth.

Happ isn't in the lineup for Wednesday's game against the Giants.

The switch-hitting Happ owns a .632 OPS against southpaws this season, and the Cubs will keep him on the bench Wednesday with left-hander Carson Whisenhunt set to take the mound for the Giants. Willi Castro will fill in as Chicago's left fielder and bat ninth.

Gusto (7-7) took the loss Wednesday as the Marlins were routed 12-1 by Atlanta, coughing up nine runs on seven hits -- including three home runs -- and five walks over 3.2 innings. He struck out two.

A leadoff homer by Jurickson Profar set the tone for the afternoon, as Atlanta went yard five times in total off Miami pitchers -- in fact, utility infielder Javier Sanoja was the only player to take the mound for the Marlins and not surrender a home run. Gusto saw his already bloated 6.00 ERA through two starts with his new club swell even further to 9.77, a mark that comes with a 1.66 WHIP and 10:8 K:BB through 15.2 innings. With Adam Mazur set to get a start Thursday, top prospect Robby Snelling knocking very loudly on the door at Triple-A, and Ryan Weathers (lat) about to begin a rehab assignment, Gusto's stint in the big-league rotation could end at any time. For the moment however, he's scheduled to make his next outing on the road early next week against the Nationals.

Smith is out of the lineup for Wednesday's game against the Reds, Fabian Ardaya of The Athletic reports.

Smith started the first two games of the series and will sit for the finale after going 1-for-6 with two walks, a solo homer and an additional run scored. Dalton Rushing will start behind the plate and bat eighth versus Cincinnati lefty Nick Lodolo.

Albies went 2-for-5 with a home run, two runs scored and five RBI in Wednesday's 12-1 win over the Marlins.

A three-run shot off Ryan Gusto in the third inning gave Albies his 13th homer of the season and his third in the last two games. The second baseman also has six multi-hit performances in the last 15 contests, a hot streak that has seen him bat .308 (20-for-65) with four doubles, four long balls, one steal, 12 runs and 15 RBI.