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Jhancarlos Lara SP | WAS
Nationals' Jhancarlos Lara: Jettisoned from 40-man roster
The Nationals designated Lara for assignment Wednesday.
Lara possesses a big arm capable of regularly reaching triple digits, but he's often struggled to throw strikes. After walking 65 batters over 68.2 innings between Double- and Triple-A in 2025, he's posted a 10.13 ERA and 22:31 K:BB across 16 frames at the Double-A level in 2026. That said, Lara is just 23 years old and could draw interest via waivers because of his upside.
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Kohl Drake SP | ARI
Diamondbacks' Kohl Drake: Demoted to minors
The Diamondbacks optioned Drake to Triple-A Reno on Wednesday.
Drake was promoted to the majors Sunday but is still looking to make his big-league debut. The 25-year-old is clearing off the active roster to make space for Mitch Bratt, who is up from Reno to start Wednesday's game in St. Louis.
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Mitch Bratt SP | ARI
Diamondbacks' Mitch Bratt: Recalled ahead of MLB debut
The Diamondbacks recalled Bratt from Triple-A Reno on Wednesday.
Bratt is set to make his major-league debut Wednesday in St. Louis with a start against the Cardinals. The left-hander was added to the 40-man roster over the offseason and earned his first big-league promotion after posting a 2.84 ERA, 0.95 WHIP and 42:12 K:BB over 44.1 innings covering 11 starts this season with Reno. Bratt recently returned from injury and threw only 48 pitches over four frames in his most recent start, so it's unlikely he'll be ready for a full allotment of pitches Wednesday.
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JR Ritchie SP | ATL
Braves' JR Ritchie: Sent back to Triple-A
Atlanta optioned Ritchie to Triple-A Gwinnett on Wednesday.
Ritchie's second stint in the big leagues lasted two weeks, with the young righty posting a 5.40 ERA, 1.40 WHIP and 16:9 K:BB in 15 innings across two starts and one relief appearance. Due to off days Thursday and Monday, Atlanta should be able to get by with four starters in the short term before filling Ritchie's vacated spot in the rotation late next week. Hurston Waldrep has given up just one run in 7.2 innings over two starts for Gwinnett since being reinstated from the 60-day injured list earlier this month and would be a logical choice to replace Ritchie in the big-league rotation.
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Matthew Boyd SP | CHC
Cubs' Matthew Boyd: Confirmed for return Thursday
Boyd (shoulder/knee) will be activated from the 15-day injured list to start Thursday's game against the Mets, Meghan Montemurro of the Chicago Tribune reports.
Cubs manager Craig Counsell previously noted that Boyd would rejoin the rotation this week, and now the specific date has been confirmed. Boyd has been sidelined since early May, first due to meniscus surgery and later because of shoulder soreness. He threw 59 pitches over four innings in his final rehab start, so Boyd will likely be somewhat limited Thursday from a workload perspective.
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Kodai Senga RP | NYM
Mets' Kodai Senga: Sent to bullpen
Mets manager Carlos Mendoza said Wednesday that Senga will be moved to the bullpen, Will Sammon of The Athletic reports.
Senga's demotion to a relief role comes after he walked five batters and allowed seven earned runs in just 3.2 innings during Tuesday's loss to the Cubs, bringing his record to 0-6 and inflating his ERA and WHIP to 10.08 and 1.92, respectively, over his seven starts on the season. Though the right-hander will be available to make his debut out of the bullpen during this weekend's series versus Philadelphia, he could be needed to fill a bulk-relief role behind an opener while the Mets still have a couple of holes in the rotation. The Mets aren't necessarily closing the door on Senga re-emerging as a starter at some point, but he'll presumably need to show improved form while working out of the bullpen for an extended period before the team goes down that road again.
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Vince Velasquez RP | KC
Cubs' Vince Velasquez: Contract selected by Cubs
The Cubs selected Velasquez's contract from Triple-A Iowa on Wednesday, Taylor McGregor of Marquee Sports Network reports.
Velasquez will give the Cubs' bullpen some length during Wednesday's doubleheader against the Mets. The veteran hurler spun 2.1 scoreless frames in his lone appearance in the majors earlier this season.
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Edward Cabrera SP | CHC
Cubs' Edward Cabrera: Officially lands on 15-day IL
The Cubs placed Cabrera on the 15-day injured list Wednesday with a strained left hamstring, Taylor McGregor of Marquee Sports Network reports.
Cabrera injured his hamstring during Tuesday's start versus the Mets when he did the splits while extending to catch a throw to first base. He will undergo an MRI on Wednesday to determine the severity of the strain. An update on Cabrera's timeline could be available later Wednesday.
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Kris Bubic SP | LAD
Royals' Kris Bubic: Resuming rehab assignment Wednesday
Bubic (elbow) is slated to make a rehab start Wednesday with Double-A Northwest Arkansas.
After landing on the injured list May 18 due to left elbow soreness, Bubic was cleared to kick off a rehab assignment at Triple-A Omaha on June 9. The left-hander was lit up for six runs (five earned) while recording just four outs in his lone outing with Omaha before being pulled off the assignment after experiencing shoulder discomfort. An MRI cleared Bubic of any major concerns with the shoulder, so he didn't have to pause his throwing program for more than a few days. Bubic made it through a two-inning live bullpen session over the weekend without issue and will now resume the rehab assignment, this time linking up with the Royals' Double-A affiliate. He'll likely need at least one more start in the minors beyond Wednesday to get fully ramped up, but Bubic would appear to have a shot at rejoining the Kansas City rotation before the All-Star break.
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Eury Perez SP | MIA
Marlins' Eury Perez: Reinstated ahead of start
The Marlins reinstated Perez (gracilis) from the 15-day injured list ahead of his scheduled start Wednesday against the Rangers.
Though Miami manager Clayton McCullough said that Perez would likely be shelved for around eight weeks after being diagnosed with a right gracilis strain May 29, the right-hander will wind up returning to the big club in just under a month. During his lone rehab start last week with Triple-A Jacksonville, Perez covered 3.2 innings and tossed 51 pitches, so he'll likely be somewhat limited from a workload perspective as he rejoins the big-league rotation. Perez should be ready to handle a more typical starter's workload following Wednesday's outing.