The Padres optioned Hawkins to Triple-A El Paso on Friday.

Hawkins ended the 2025 season with Double-A San Antonio, where he appeared in 13 games and finished with a 1.69 ERA, 1.31 WHIP, two saves and a 20:10 K:BB across 16 innings. He'll open the 2026 season in Triple-A and could make his major-league debut if the Padres need added depth to their bullpen.

Duran threw a clean inning during Friday's Grapefruit League game against the Orioles. He struck out two.

Duran is now up to three scoreless frames with six punchouts and no walks during spring training. Following a trade away from the Twins at least year's deadline, the hard-throwing right-hander is all set to resume his duties as Philadelphia's closer to begin 2026. Duran delivered a 2.18 ERA, 0.92 WHIP and a sparkling 27:1 K:BB over 20.2 regular-season innings for the Phillies a year ago, successfully converting 16 of his 19 save opportunities.

The Nationals optioned Eder to Triple-A Rochester on Friday.

Eder has pitched 6.2 frames this spring in Grapefruit League play, yielding four runs (two earned) with a 6:6 K:BB. The left-hander will likely be part of Rochester's rotation to begin the season, but all nine of his big-league appearances have been out of the bullpen. He could fill either role with the Nationals when called upon.

Holmes struck out nine and walked one over five scoreless, no-hit innings in Thursday's Grapefruit League game against the Pirates.

The right-hander built up to 64 pitches (41 strikes) as he dominated a Pittsburgh lineup that featured most of its likely Opening Day starters, including Bryan Reynolds, Ryan O'Hearn and Marcell Ozuna. Holmes has yet to allow an earned run this spring, posting a 16:6 K:BB through 12.1 innings, and he's locked into an Opening Day rotation spot due to injuries to Spencer Schwellenbach (elbow), Hurston Waldrep (elbow) and Joey Wentz (knee).

With Matthew Boyd named Chicago's Opening Day starter, Imanaga could be the team's No. 3 pitcher behind Cade Horton, Jordan Bastian of MLB.com reports.

Imanaga was seen as an option for the Opening Day assignment, but Chicago will instead turn to Boyd for the third time in his career and first with the Cubs. The team hasn't officially announced its plans behind Boyd, though slotting Horton second and Imanaga third would allow Chicago to go lefty-righty-lefty. If Imanaga is the No. 3 starter, his first appearance of the regular season would be March 29 against the Nationals at Wrigley Field.

Hoeing (elbow) will undergo flexor tendon surgery and miss the entire 2026 season, Kevin Acee of the San Diego Union-Tribune reports.

Hoeing was shut down from throwing earlier this month and has now opted for season-ending surgery. The 29-year-old right-hander spent the bulk of his 2025 campaign with Triple-A El Paso but pitched in seven games out of the bullpen for the Padres, turning in a 3.38 ERA, 1.50 WHIP and 5:3 K:BB across eight innings.

Ferguson will open the season on the injured list due to an oblique injury, Gordon Wittenmyer of The Cincinnati Enquirer reports.

Manager Terry Francona said that it is a mild oblique injury and that Ferguson will be out "a couple of weeks" and that "he has to heal the way it heals," per Charlie Goldsmith of Fox 19 Now Cincinnati. The southpaw was signed by the Reds in December and is likely to fill a middle-relief role when healthy.

Manaea gave up three runs on six hits with four strikeouts and one walk over 2.2 innings during Thursday's Grapefruit League game against the Cardinals. According to Max Goodman of NJ.com, the left-hander averaged 89 mph with his fastball but said he isn't concerned by the lower velocity.

Manaea averaged 91.9 mph with his fastball last season, but he was limited to 15 appearances due to elbow issues and struggled to a 5.64 ERA. Pitchers will often experience a lower velocity during spring training while building up, so it's not necessarily a major concern. However, seeing Manaea's fastball regain some zip before Opening Day would go a long toward reassuring fantasy GMs thinking about using a late-round pick on the veteran southpaw.

Kerkering (hamstring) will throw a live batting practice session Saturday, Scott Lauber of The Philadelphia Inquirer reports.

The right-handed reliever has been slowed since the start of camp by a Grade 1 right hamstring strain, and this will be the second time he's faced hitters since the injury. If things go off without a hitch Saturday, Kerkering's Grapefruit League debut should be around the corner. Phillies manager Rob Thomson said Thursday that Kerkering will "possibly" have enough time to be ready for Opening Day.

The Cubs optioned Little to Triple-A Iowa on Thursday.

Little was unable to find his footing during spring training with four earned runs allowed over 4.2 frames, so he won't make Chicago's Opening Day bullpen. The 25-year-old made just two big-league appearances last season but had a 3.46 ERA across 26 innings with the Cubs in 2024.