Wade is absent from the lineup for Wednesday's game in Houston.

Left-hander Framber Valdez will start for the Astros, so the lefty-hitting Wade will begin the series finale on the bench. Casey Schmitt will fill in at first base and bat fifth.

Busch is out of the lineup for Wednesday contest against the Athletics.

Southpaw Jeffrey Springs is on the bump for the Athletics, so the left-handed-hitting Busch will begin the series finale on the bench. Justin Turner will start at first base and bat cleanup for the Cubs.

Burleson is out of the lineup for Wednesday's game against the Angels.

Through the first six games of the season, the Cardinals have faced left-handed starting pitchers two times, and the lefty-hitting Burleson has checked out of the lineup on both occasions. The right-handed-hitting Luken Baker will replace Burleson as the Cardinals' designated hitter Wednesday while southpaw Yusei Kikuchi takes the hill for the Angels.

Encarnacion-Strand (hand) will start at first base and bat sixth in Wednesday's contest versus the Rangers.

Encarnacion-Strand didn't play Tuesday after leaving Monday's game following a hit-by-pitch on the right hand, but it will be just a one-game absence for the infielder. The 25-year-old is 4-for-14 with one home run in the early going this season.

Freeman (ankle) is absent from Tuesday's lineup against Atlanta.

This is the second straight game during which Freeman is not in the lineup for the Dodgers after aggravating his right ankle at home while in the shower Monday. This is the same ankle that the 35-year-old sprained in 2024 and that has yet to completely heal. He underwent imaging and the X-rays came back negative Tuesday, Fabian Ardaya of The Athletic reports. As Freeman nurses his ankle, Enrique Hernandez has the start at first base again.

Rodriguez is absent from the lineup for Tuesday's game against the Rays.

Rodriguez has garnered three starts at first base and one start at catcher in the early going, but he will begin Tuesday's tilt on the bench. Enmanuel Valdez will handle first base, and Joey Bart will do the catching for Pittsburgh.

Encarnacion-Strand (hand) is out of the lineup for Tuesday's game against the Rangers.

The 25-year-old departed Monday's series opener after being hit by a pitch on the right hand and will be absent from the starting nine for at least one game. Encarnacion-Strand already had X-rays come back negative and could be available off the bench, per Reds manager Terry Francona, Charlie Goldsmith of the Dayton Daily News reports. Jeimer Candelario is shifting to first base Tuesday while Santiago Espinal receives a start at the hot corner.

Contreras is absent from the lineup in Tuesday's game versus the Angels.

Contreras is still looking for his first hit of the season, having gone 0-for-18 with eight strikeouts in the Cardinals' first four games. Alec Burleson will cover first base and Nolan Gorman will be the DH on Tuesday while Contreras regroups.

Busch went 3-for-6 with a home run, two total runs and four total RBI against the Athletics in an 18-3 win Monday.

Busch was one of four Chicago players with three or more hits in the offensive onslaught. He hit the first homer of the game for Chicago, knocking a two-run shot to right-center field in the first inning. The long ball was the first extra-base hit of the season for Busch, who had gone just 4-for-18 at the plate prior to Monday's big performance.

Flores went 2-for-4 with a homer and four RBI in Monday's 7-2 victory over the Astros.

The 33-year-old drew his fourth consecutive start and anchored the Giants' offense as the designated hitter. Flores opened the game's scoring with an RBI single in the second inning. The veteran then cracked a 350-foot, three-run homer to the Crawford Boxes in the sixth inning to stretch the lead to 5-0. Through his first 16 plate appearances, Flores is slashing .267/.313/.867 with three homers and eight RBI.