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Equanimeous St. Brown WR | SF
Bears' Equanimeous St. Brown: Not able to practice
St. Brown (hamstring) didn't practice Wednesday.
St. Brown had replaced Chase Claypool as Chicago's No. 3 receiver prior to injuring his hamstring during Thursday's 40-20 win over Washington. It's not a role that will likely come with much target volume, regardless of whether St. Brown, Tyler Scott or another player is the one getting snaps in three-receiver sets alongside starting wideouts DJ Moore and Darnell Mooney.
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Amon-Ra St. Brown WR | DET
Lions' Amon-Ra St. Brown: Officially limited Wednesday
St. Brown (abdomen) practiced in a limited capacity Wednesday.
St. Brown didn't log any on-field work during Week 5 prep before the Lions deemed him inactive ahead of this past Sunday's win over the Panthers. Head coach Dan Campbell expressed optimism about St. Brown's chances of playing Week 6 against the Buccaneers when speaking to Justin Rogers of The Detroit News and Tim Twentyman of the Lions' official site earlier this week, and the receiver's return to practice seemingly backs up Campbell's hopefulness. Ultimately, St. Brown likely will need to get through the Lions' next two practices unscathed before the Lions provide some clarity on his status heading into Sunday.
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Treylon Burks WR | WAS
Titans' Treylon Burks: Remains sidelined Wednesday
Burks (knee) didn't practice Wednesday, Jim Wyatt of the Titans' official site reports.
Burks, who has missed two straight games, now has two more opportunities to get back on the practice field ahead of Sunday's game against the Ravens in London. If Burks remains out this weekend, Nick Westbrook-Ikhine, Chris Moore and Kyle Philips would be in store for expanded roles at receiver behind No. 1 wideout DeAndre Hopkins.
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Odell Beckham Jr. WR | NYG
Ravens' Odell Beckham: Opens Week 6 with limited practice
Beckham (ankle) was a limited participant in practice Wednesday, Jim Wyatt of the Titans' official site reports.
Beckham missed two games due to an ankle injury before returning to action for the Ravens' Week 5 loss to the Steelers. The veteran wide receiver appears to still be bothered by the injury, but he didn't suffer any reported setbacks. Beckham will have two more opportunities to reach full participation and avoid an injury designation for Sunday's game against the Titans.
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Irvin Charles WR | SEA
Jets' Irvin Charles: Signed to active roster
The Jets signed Charles to the active roster from the practice squad Wednesday.
Charles was called up to make his NFL debut versus the Broncos on Sunday, and it looks like he could get another chance to see game action Week 6 against Philadelphia. Against Denver, he failed record any stats and played 20 out of 22 total snaps on special teams.
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Treylon Burks WR | WAS
Titans' Treylon Burks: Not spotted at practice
Burks (knee) wasn't on the field Wednesday for the portion of practice open to the media, Jill Jelnick of Fox Sports reports.
Burks has missed the Titans' last two games and didn't practice in any capacity last week, and it looks like he's headed for another absence to begin Week 6 prep. The second-year has two more chances to get back on the practice field before the Titans decide whether to give him an injury designation for this Sunday's game against the Ravens.
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Marquise Brown WR | PHI
Cardinals' Marquise Brown: Not practicing
Brown isn't practicing Wednesday, Jose M. Romero of The Arizona Republic reports.
The Cardinals haven't revealed if Brown is dealing with an injury, but he's coming off a productive outing in this past Sunday's loss to the Bengals, in which he caught four of 10 targets for 61 yards and a touchdown. He's been consistently productive this season, with at least 57 total yards in each game and a touchdown in three of the past four.
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Tank Dell WR | HOU
Texans' Tank Dell: Not expected to play Week 6
Dell (concussion) didn't practice Wednesday and isn't expected to be available for Sunday's matchup against the Saints, Aaron Wilson of KPRC 2 Houston reports.
Dell is reportedly making progress as he works to clear the NFL's five-step concussion protocol, but the rookie wideout looks like he would need to exceed current expectations in order to be cleared for Week 6. The Texans have a bye Week 7, so missing one contest would allow Dell almost three full weeks to recover in time for the team's Oct. 29 matchup against the Panthers in Week 8.
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Jordan Addison WR | MIN
Vikings' Jordan Addison: Chance to step in as No. 1 wideout
Addison could see additional targets and snaps over Minnesota's next four games after No. 1 receiver Justin Jefferson (hamstring) was placed on injured reserve Wednesday, Craig Peters of the Vikings' official site reports.
Addison and K.J. Osborn are likely to see more looks than usual while Jefferson -- who averaged 10.6 targets per game through the first five weeks of the season -- recovers from his hamstring injury. The rookie already has been a strong contributor to Minnesota's offense with more than 50 yards in four of his first five games to go along with three touchdowns, though he also had a game with no catches Week 4 at Carolina (when Kirk Cousins attempted only 19 passes). Jefferson will miss his first game this Sunday against a leaky Chicago defense that has given up 31.4 points per game, so Addison will have a nice opportunity to step up immediately. Vikings head coach Kevin O'Connell said Wednesday that he expects to "hit the gas" with Addison this week, noting that everything with the 21-year-old has been positive since he was drafted apart from his July citation for excessive speeding, per Andrew Krammer of the Minneapolis Star Tribune.
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K.J. Osborn WR | TEN
Vikings' K.J. Osborn: Could step up with Jefferson on IR
Osborn could be in line for additional opportunities over the next four games after Minnesota placed Justin Jefferson (hamstring) on injured reserve Wednesday, Craig Peters of the Vikings' official site reports.
In Jefferson's absence, Osborn and Jordan Addison are projected to serve as Minnesota's top two wide receivers, beginning with a Week 6 matchup against Chicago's shaky secondary. Jefferson drew 53 targets through five games before getting hurt, and those 10.6 targets per game are likely to be distributed primarily between Osborn, Addison and tight end T.J. Hockenson. Osborn has yet to reach 50 yards in a game this season, but he averaged 87.5 receiving yards on 8.3 targets over the final four weeks of the 2022 campaign.