Holmes (11-8) took the loss against the Phillies on Wednesday, allowing four runs on six hits and three walks while striking out five and hitting two batters over four innings.

The right-hander labored through a tough opening frame, loading the bases with no outs before surrendering an RBI knock to J.T. Realmuto and plunking Max Kepler to put New York in an early hole. Holmes settled in after that, working through the next three innings without giving up a run despite allowing four additional baserunners. The 32-year-old ran into trouble in the fifth however, surrendering two hits to start the inning and allowing another run before being lifted from the game. He allowed his most runs over his past five starts. Holmes will carry a 3.75 ERA, 1.35 WHIP and 122:62 K:BB into his next scheduled start at home against the Padres.

Irvin (8-12) took the loss against the Marlins on Wednesday, allowing four runs (three earned) on five hits while striking out four over five innings.

The right-hander was incredible early, retiring 15 of the first 17 batters he faced while cruising through five scoreless frames. However, Irvin's outing fell apart in the sixth after a fielding error put Maximo Acosta on base, sparking a rally that included three hits before being lifted with two runners aboard -- both of which came around to score. The tough-luck inning extended Irvin's skid to seven losses over his last eight outings, including five straight defeats, as he continues to search for a turnaround.

Perez didn't factor into the decision against the Nationals on Wednesday, allowing three runs on seven hits while striking out seven over 5.2 innings.

Perez looked dominant early, striking out five of the first six batters he faced and allowing just three hits through his first five frames, before unraveling in the sixth and surrendering four straight hits to end his day. After a stellar July, the young right-hander has struggled of late, posting a 7.84 ERA across his last seven outings (32 innings). Perez now owns a 4.67 ERA, 1.11 WHIP and 79:28 K:BB across 81 innings this season and will look to replicate his early-inning success from Wednesday in his next scheduled start against the Rockies, a matchup that should be favorable given Colorado's .307 OBP since the All-Star break. He'll have to contend with the hitter-friendly environment of Coors Field, however.

Rodriguez (8-8) earned the win Wednesday over the Giants, allowing two hits and two walks over 6.1 scoreless innings. He struck out six.

It was another strong effort from Rodriguez, who held San Francisco to just one hit through his first six innings. The left-hander has turned a corner recently, logging wins and quality starts in three straight outings -- he's allowed just one run on six hits across 18.1 innings in that span. Rodriguez has lowered his ERA to 4.98 with a 1.55 WHIP and 76:55 K:BB across 26 starts (137.1 innings) this season. He's currently slated for a rematch with the Giants at home his next time out.

Peralta (16-6) took the loss Wednesday against the Rangers, allowing five runs on six hits and two walks across five innings. He struck out nine.

Peralta matched a season high with five runs allowed in the loss, his first defeat in seven starts. The right-hander had been nearly untouchable coming Wednesday -- he'd held opponents scoreless in each of his prior five outings (28 innings), striking out 35 while allowing just nine hits in that span. Overall, Peralta's ERA sits at 2.69 with a 1.09 WHIP and 185 strikeouts through 30 starts (163.2 innings) this year. He'll look to get back on track his next time out, tentatively scheduled to come next week at home against the Angels.

Gore (shoulder) is scheduled to be activated off the 15-day injured list to pitch Thursday against the Marlins, Spencer Nusbaum of The Washington Post reports.

The left-hander landed on the shelf in late August due to shoulder inflammation and will rejoin the Nationals after spending the 15-day minumum on the injured list. In his last two starts before heading to the IL, Gore allowed six earned runs with eight strikeouts and six walks across 9.1 innings.

Mets manager Carlos Mendoza said Wednesday that Megill is being further evaluated as the team seeks to find the source of the pitcher's right elbow discomfort, Laura Albanese of Newsday reports.

Megill has been shut down after he experienced tightness in his pitching arm following his most recent rehab start for Triple-A Syracuse on Sunday. Mendoza noted Wednesday in regard to Megill's status that Tommy John surgery has not been discussed, though that doesn't necessarily mean it won't be in the future. The righty has been out since mid-June due to elbow trouble, and his availability for the rest of the season is very much in doubt.

The Cubs reinstated Taillon (groin) from the 15-day injured list ahead of his scheduled start Wednesday in Atlanta, Maddie Lee of the Chicago Sun-Times reports.

Reliever Ethan Roberts was optioned to Triple-A Iowa in a corresponding move, while right-hander Javier Assad was moved to the bullpen to clear room in the rotation for Taillon, who spent the minimum amount of time on the shelf. Prior to being activated, Taillon tossed 3.2 innings and 68 pitches in a rehab start with Iowa on Thursday, so his workload could be somewhat suppressed as he makes his 20th appearance of the season for the big club.

Strider (5-13) took the loss Tuesday, allowing two runs on six hits and three walks over six innings as Atlanta fell 6-1 to the Cubs. He struck out eight.

While he got outdueled by Chicago rookie Cade Horton, Strider looked a little more like his usual dominant self in this one. The Atlanta right-hander's eight Ks were his highest total since July 18, and he racked up 32 called or swinging strikes among his 97 pitches (60 total strikes). Strider's quality start was his ninth in 20 outings this season, and over his last three trips to the mound he sports a 3.00 ERA and 1.22 WHIP, albeit with a lackluster 12:8 K:BB in 18 innings. He'll look to build on this performance in his next start, which lines up to come on the road early next week against the Nationals.

Patrick didn't factor into the decision Tuesday against Texas, allowing three runs on three hits and three walks with six strikeouts across 4.1 innings.

A game-tying two-run home run by Michael Helman with one out in the fifth inning ended Patrick's start, as he was pulled at 80 pitches following the long ball. The 27-year-old was relegated to Triple-A in early July, but he's been called up to make three starts for the Brewers since, tallying a 4.91 ERA and a 17:7 K:BB across 14.2 innings during that stretch. He's expected to return to Triple-A Nashville without making another big-league start.