De Los Santos (knee) struck out a batter and allowed one walk and no hits over a scoreless inning of relief Friday in the Astros' 7-4 loss to the Marlins in Grapefruit League play.

The reliever made his spring debut after completing his recovery from the right knee strain he suffered early in camp. Manager Joe Espada told Brian McTaggart of MLB.com that De Los Santos is scheduled to pitch again Monday in an exhibition against Triple-A Sugar Land. If all goes well in that outing, De Los Santos should be able to secure a spot in the Opening Day bullpen.

The Pirates optioned Sanders to Triple-A Indianapolis on Sunday.

Sanders allowed four runs and struck out 10 over 7.2 innings during spring training, but it wasn't enough to get him a place on the Opening Day roster. The right-hander surrendered six earned runs across 6.2 frames in his first taste of the majors last year.

Mets manager Carlos Mendoza said Sunday that Kimbrel won't be included on the Mets' Opening Day roster, Max Goodman of NJ.com reports.

The nine-time All-Star has been attending spring training as a non-roster invitee and struck out five batters while allowing three earned runs on four hits and two walks over six innings in the Grapefruit League. Kimbrel's minor-league deal is believed to include multiple opt-out dates, but Mendoza told Goodman that the 37-year-old righty is "leaning" toward staying in the organization and reporting to Triple-A Syracuse to begin the season.

The Phillies reassigned Trivino to minor-league camp Sunday.

Between stops with the Giants, Dodgers and Phillies last season, Trivino accrued a 3.97 ERA, 1.34 WHIP and 37:18 K:BB in 47.2 innings. After reaching free agency this winter, he settled for a return to Philadelphia on a minor-league deal. The 34-year-old righty was roughed up for nine runs (eight earned) on 11 hits and six walks over nine innings this spring. Unless he chooses to opt out of his contract, Trivino is poised to begin the season at Triple-A Lehigh Valley.

Kerkering (hamstring) will begin the regular season on the injured list, Matt Gelb of The Athletic reports.

The right-hander has made just one Grapefruit League appearance this spring while working his way back from a Grade 1 hamstring strain, so he'll get some more time to build up before joining the Phillies. Once healthy, Kerkering is expected to fill a setup role after recording four saves and 19 holds with a 3.30 ERA, 1.37 WHIP and 65:27 K:BB across 60 regular-season innings last year.

The Phillies optioned Shugart to Triple-A Lehigh Valley on Sunday.

Shugart was acquired from the Pirates in January but has missed out on the Opening Day roster after posting a 3.72 ERA and 7:7 K:BB over 9.2 Grapefruit League innings. The right-hander had a 3.40 ERA and 1.11 WHIP across 35 appearances with Pittsburgh last year and should be up with Philadelphia at some point this season when bullpen depth is needed.

Texas manager Skip Schumaker said Saturday that Latz's chances of earning a roster spot will not be affected by the results of his final spring start, Kennedi Landry of MLB.com reports.

Latz allowed nine runs on eight hits and two walks over three innings in a Cactus League outing Thursday, inflating his spring ERA to 8.22. "You don't make or break a team or a position on the last day of spring, or last couple days of spring," Schumaker said of Latz. The Rangers' main concern is the southpaw's inability to maintain velocity deeper into games this spring, which could prevent him from providing at least five effective innings in a start. Latz's main competition for the final spot in the rotation is Kumar Rocker, who has excelled his last two times out but still has things the organization would like him to work on, such as his changeup usage. Non-roster veterans Austin Gomber and Cal Quantrill are also still in the mix.

The Phillies released Mayza on Sunday and re-signed him to a major-league contract.

The 34-year-old lefty joined Philadelphia as a non-roster invitee in January and was able to earn a roster spot after giving up five earned runs with a 10:2 K:BB over 8.1 innings during spring training. Mayza made just 15 regular-season appearances last year due to a shoulder injury but was a reliable high-leverage arm as recently as 2023, when he recorded a save and 22 holds with a 1.52 ERA for the Blue Jays over 69 outings.

Bowman exercised the opt-out clause in his minor-league deal with the Twins on Sunday and elected to become a free agent, Jon Heyman of the New York Post reports.

Bowman had been scheduled to pitch Sunday, but he'll instead hit the open market. The veteran right-hander shouldn't have much trouble finding a suitor after an excellent spring between his stops with the Twins and Team Israel. In addition to allowing just one unearned run over 5.1 innings in the Grapefruit League, Bowman tossed three scoreless frames over two World Baseball Classic appearances.

The Diamondbacks informed Loaisiga on Saturday that he's secured a spot on the Opening Day roster, Jorge Castillo of ESPN.com reports.

Arizona will officially add Loaisiga to the 26-man roster shortly before Thursday's season opener in Los Angeles. The right-hander posted a 7:2 K:BB while allowing three earned runs on eight hits over seven innings during the Cactus League. While Loaisiga is likely to begin the season in middle relief, he could earn higher-leverage opportunities quickly in an unsettled bullpen.