The Red Sox will place Hicks on the 15-day injured list prior to Friday's game in Arizona with a right shoulder injury, Chris Cotillo of MassLive.com reports.

Hicks gave up four runs while recording just one out in an appearance Wednesday versus the Guardians and holds an 8.20 ERA and 15:12 K:BB over 18.2 innings during his time with the Red Sox. He would be eligible for activation Sept. 19, but between the nature of the injury and Hicks' struggles, his season could be over.

Williams (3-6) took the loss against Houston on Wednesday, allowing four runs on one hit and three walks while striking out two batters over two-thirds of an inning.

The game was tied 4-4 when Williams took the mound in the eighth inning. He immediately found himself in trouble, giving up a double and a walk to the first two batters he faced. Williams fanned two of the next three hitters to nearly wiggle out of the mess, but he then walked in a run before giving way to Camilo Doval, who allowed all three of his inherited runners to score. Williams has been prone to blowups this season -- he's given up multiple runs in 10 outings, and in half of those instances he's surrendered at least three runs. Despite an impressive 78:23 K:BB over 53 frames, his ERA sits at an ugly 5.60 on the season.

Burke earned a hold against Kansas City on Wednesday by pitching a clean sixth inning.

Burke entered with the Angels up by a run in the sixth inning. He made quick work of the Royals, retiring the side in order on 10 pitches. Burke is having a solid season, posting a 3.09 ERA, 1.25 WHIP and 46:18 K:BB over 63 appearances spanning 55.1 frames. He's already reached a career-best mark with 14 holds.

Blewett (elbow) allowed two runs on three hits over an inning in his first rehab appearance with Triple-A Norfolk on Wednesday.

It was Blewett's first appearance in a game since he went down with right elbow discomfort just before the All-Star break. He'll need a few more rehab outings but could be activated from the 60-day injured list when first eligible Sept. 15.

Detmers earned the save in Wednesday's 4-3 win over the Royals, striking out two in a perfect ninth inning.

With Kenley Jansen pitching three out of the last four days, Detmers was called upon to protect a one-run lead and shut down the Royals on 13 pitches. The right-hander hasn't allowed a run in 12 of his last 13 appearances and has given manager Ron Washington reason to utilize him in high-leverage scenarios like Wednesday's when necessary.

Dana didn't factor into the decision against the Royals on Wednesday, allowing two runs (one earned) on two hits and one walk while striking out four over five innings.

Making his first start of the season and the fourth of his career, Dana was sharp outside of the third inning, when a single, a walk and an error combined to bring home two runs for Kansas City. Otherwise, the 21-year-old faced the minimum in each of his other four frames, showing good poise and efficiency (70 pitches) in his first big-league outing since May. With Wednesday's performance, Dana should be in line for at least another turn as the Angels look to evaluate him down the stretch.

Cantillo (4-3) earned the win over the Red Sox on Wednesday, allowing one run on five hits and two walks while striking out seven over six innings.

Cantillo was impressive against a tough Boston lineup, completing six innings for the first time this season. The southpaw's lone blemish came in the fourth inning when Boston scratched across a run on three singles, but he quickly rebounded to retire seven of the final eight batters he faced. Wednesday's performance continued a strong stretch in which Cantillo has now allowed exactly one run in three straight outings. Across his nine starts this year, the 25-year-old has posted a 3.68 ERA and 51:24 K:BB over 44 innings.

Ellard will serve as the White Sox's opening pitcher for Thursday's game against the Twins, Scott Merkin of MLB.com reports.

Ellard will work as an opener for the second time in four days after coughing up one unearned run in 1.2 innings in Monday's 6-5 win over Minnesota. Jonathan Cannon is expected to pitch in bulk relief after Ellard exits the game.

Topa (1-5) was charged with the loss and a blown save in a 4-3 defeat to the White Sox on Wednesday, allowing one run on two hits and no walks with one strikeout in two-thirds of an inning.

That's consecutive blown saves for Topa, who has now given up at least one run in four straight outings. Given the right-hander's recent struggles, it wouldn't be surprising to see manager Rocco Baldelli turn to a different high-leverage arm, such as Cole Sands or Kody Funderburk, for Minnesota's next save chance. Topa has a 4.03 ERA and 1.45 WHIP over 58 innings this season.

Leasure picked up the save in a 4-3 win over the Twins on Wednesday, allowing one hit and one walk with no strikeouts in a scoreless ninth inning.

Leasure turned in his sixth save of the season, and it was also his fourth consecutive scoreless outing. The right-hander had a 4.62 ERA for the year through July 28, but he's been exceptional out of the Chicago bullpen since the start of August. Over his last 14 innings, Leasure has a 2.57 ERA, 0.71 WHIP and 22:4 K:BB with four saves to enhance his ERA to 4.08 for the campaign.