Horwitz is out of the lineup for Wednesday's game against the Tigers.

The left-handed-hitting Horwitz will exit the lineup for just the second time in nine games while the Pirates face off against reigning American League Cy Young Award winner Tarik Skubal. Platoon mate Jared Triolo will step in at first base in place of Horwitz, who is batting .228 with one home run, seven RBI and nine runs through his first 26 games with the Pirates.

Kemp is out of the lineup for Wednesday's game against the Marlins.

For the first time since receiving his first big-league call-up June 7, Kemp will head to the bench. The rookie has held his own at the plate through his first 10 starts in the majors, batting .278 with a walk, a stolen base, six runs and four RBI. Though he'll cede his spot in the infield to Edmundo Sosa on Wednesday, Kemp should continue to handle an everyday role until the Phillies get first baseman Bryce Harper (wrist) back from the injured list.

Encarnacion-Strand is not in the lineup for Wednesday's game against the Twins.

Encarnacion-Strand started the first seven contests upon his activation from the 10-day injured list and slugged home runs in each of the first three of those games. However, he's gone just 2-for-21 with seven strikeouts in his last six games, and Wednesday will be the second time across the last four tilts that he's been out of the lineup. Spencer Steer and Santiago Espinal will handle corner-infield duties for the Reds.

Lowe went 2-for-5 with a double, a solo home run and a second run scored in Tuesday's 10-6 loss to the Rockies.

The first baseman took Anthony Molina deep in the eighth inning as the Nationals tried to mount a late comeback from a 10-1 deficit. Lowe's up to 10 homers on the season, but Tuesday's effort was only his second multi-hit performance in June, a month in which he's slashing .231/.286/.385 in 15 games.

Toglia went 3-for-5 with two home runs and three RBI in Tuesday's 10-6 win over the Nationals.

In his second game back in the majors following a promotion from Triple-A Albuquerque, Toglia took Michael Soroka deep in the fourth inning before getting hold of a Jackson Rutledge cutter in the seventh, leading the charge as the Rockies tied a franchise record with seven homers on the night. Toglia's power has never been in question, only his ability to make enough contact -- through 56 games for Colorado this season he's produced eight home runs and 24 RBI, but a .205/.273/.385 slash line and a ghastly 38.4 percent strikeout rate.

Burleson went 3-for-5 with a solo homer and two total RBI in Tuesday's win over the White Sox.

Burleson tallied his sixth multi-hit game and second three-hit effort in the month of June. His big blast came in the seventh inning off lefty Tyler Alexander to extend the lead to 9-2. Burleson is now 7-for-14 this season against left-handed pitching and his three-hit night brought his season average to .305.

Arraez went 3-for-5 with one RBI and one run scored in Tuesday's 8-6 loss to the Dodgers.

Arraez is 10-for-31 (.323) over his last seven games, a span that has seen him rack up three doubles, three RBI and five runs scored. The infielder is up to a .280/.312/.396 slash line with three homers, 27 RBI, 32 runs scored, three stolen bases, 16 doubles and three triples over 66 contests. Arraez continues to provide steady contact with a tiny 1.7 percent strikeout rate -- he hasn't struck out since May 25 versus Atlanta.

President of baseball operations Buster Posey said Tuesday that the Giants plan to continue developing Eldridge as a first baseman after San Francisco acquired Rafael Devers from the Red Sox on Sunday, Ali Thanawalla of NBC Sports Bay Area reports. "I see [Eldridge's] development path as the same," Posey said during Devers' introductory press conference. "He's going to keep playing first, keep developing at the plate. It's a conversation Raffy and I have had already about Bryce and the future we potentially see him having. Par for the course for him, going forward."

Though Boston had been using Devers exclusively at designated hitter this season, both Posey and manager Bob Melvin said that the 28-year-old will eventually get some exposure to first base, where he could end up settling as an everyday player if he proves he can handle the position. Even at first base, Eldridge is viewed as a low-end defender, so moving him to a corner-outfield spot in an effort to expedite his arrival to the majors doesn't seem to be under serious consideration. The 20-year-old profiles as an enticing long-term fantasy asset due to his power potential, and he already mashed his way to Triple-A Sacramento earlier in June, overcoming a spring wrist injury to generate a .862 OPS in 34 games at Double-A Richmond. He's struggled out of the gate at Sacramento with a .143/.213/.286 with a 34 percent strikeout rate through 11 contests, and his slow start plus the acquisition of Devers and the quality production the Giants have received from Dominic Smith (.919 OPS in 11 games) so far this month seem likely to delay Eldridge's big-league debut. Eldridge is still seen as the Giants' first baseman of the future, but his chances of being a meaningful fantasy contributor in 2025 appear to be fading.

Schmitt (foot) will start at third base and bat sixth Tuesday against the Guardians, Susan Slusser of the San Francisco Chronicle reports.

After fouling a ball off his foot Sunday, Schmitt missed out on the starting nine Monday, though he managed to appear as a pinch hitter. He'll now rejoin the lineup as San Francisco's third baseman while Rafael Devers makes his Giants debut as the DH.

Lowe is out of the lineup for Monday's game against the Rockies.

Even though he owns a lowly .209/.250/.302 slash line against left-handed pitching this season, the lefty-hitting Lowe typically starts in those matchups, but he'll get Monday off while southpaw Carson Palmquist toes the rubber for Colorado. Andres Chaparro will step in for Lowe at first base and will bat cleanup.