White rushed 17 times for 65 yards and a touchdown while corralling all three of his targets for 21 yards in Sunday's 30-19 win over the 49ers.

White got the nod in place of injured starter Bucky Irving (foot/shoulder) for the second consecutive week, rewarding fantasy managers with his third touchdown over that span. The 26-year-old White finished below four yards per carry in both spot-starts, but his nose for the goal line helped cement another strong fantasy score. No. 3 RB Sean Tucker (6-25-1) remained a distant second in carries behind White, but the former was able to vulture a touchdown from the fill-in starter this time around. The Buccaneers have an extra day off before hosting the Lions on Monday Night Football in Week 7, so White's managers should monitor Irving's availability leading up to that contest before deciding whether to deploy White in their lineups.

Kamara carried the ball 10 times for 31 yards and caught all five of his targets for 45 yards in Sunday's 25-19 loss to the Patriots.

After dealing with an ankle injury during the week in practice, Kamara didn't seem particularly bothered by the issue as he saw at least 15 touches for the fourth time in the last five games and produced 70-plus scrimmage yards for the third time in that span. Kamara has 314 rushing yards and a 22-122-0 receiving line on 26 targets through six contests, but a Week 1 rushing TD has been his only trip to the end zone so far. He'll look to end his scoring drought in Week 7 against the Bears.

Henderson carried the ball nine times for 27 yards and caught one of two targets for nine yards in Sunday's 25-19 win over the Saints.

The results were meager, but Henderson still out-gained Rhamondre Stevenson by 18 scrimmage yards, although he finished one rushing yard behind quarterback Drake Maye for the team lead. Henderson has yet to reach even 40 rushing yards or 60 scrimmage yards in a game this season, and the rookie will likely remain stuck in a timeshare with Stevenson heading into a Week 7 clash with the Titans.

Williams rushed the ball 13 times for 29 yards in Sunday's 30-27 loss to the Panthers. He added five receptions on eight targets for five yards.

The Cowboys were forced into a relatively pass-heavy game script as they kept pace with the Panthers. That limited Williams to a season-low 13 carries, but the primary issue was his lack of efficiency. Williams' longest rush went for only six yards, and his longest reception was good for only nine yards. The positive takeaway is that Williams earned 18 touches and the next closest Dallas back (Jaydon Blue) had only three. Williams should have a strong chance to bounce back in Week 7 against Washington.

Stevenson carried the ball 13 times for 18 yards in Sunday's 25-19 win over the Saints. He failed to catch his only target.

The fifth-year RB avoided committing another fumble, but that was about the only silver lining to his performance. Stevenson has failed to reach 40 rushing yards in four straight games, producing a woeful 2.7 YPC over that stretch, and only a couple Week 5 rushing TDs have salvaged any real fantasy value for him during that span. TreVeyon Henderson hasn't had much more success, so the duo will likely continue to work in a timeshare in Week 7 against the Titans.

Walker rushed 10 times for 34 yards and brought in his only target for three yards in the Seahawks' 20-12 win over the Jaguars on Sunday.

Walker logged two fewer carries than Zach Charbonnet, but he outgained his teammate by 10 rushing yards, as neither back was particularly efficient during the defense-centric battle. The fourth-year pro's yardage total represented quite the downturn after he'd topped the 80-yard mark in each of the previous two games, and Charbonnet's workload is somewhat of a concern for the moment for Walker's fantasy managers. It remains to be seen if a similar timeshare will apply moving forward, but neither player has a particularly bright outlook for a Week 7 home matchup against a tough Texans defense on Monday night, Oct. 20.

Jacobs rushed the ball 18 times for 93 yards and two touchdowns in Sunday's 27-18 win over the Bengals. He added five receptions on five targets for 57 yards.

The Packers had an efficient offensive day, both on the ground and through the air. Jacobs unsurprisingly led the way as a rusher, ripping off long runs of 16 and 14 yards -- the latter of which went for a touchdown to kick off the fourth quarter. He also turned in his third straight game with at least four catches. Despite not reaching 100 rushing yards in any game, Jacobs has found the end zone six times in five contests and remains one of the most reliable fantasy contributors at running back.

McCaffrey took 17 carries for 54 yards and a touchdown while hauling in seven of eight targets for 57 yards in Sunday's 30-19 loss to the Buccaneers.

McCaffrey scored his first regular-season touchdown since the 2023 campaign after being held out of the end zone as a runner over his previous five starts this year and all four healthy appearances in 2024. The dual-threat superstar has been in the doldrums as a pure rusher this season (3.1 YPC), but he has offset that with WR1 production as a receiver (46-444-3). In fact, CMC has finished with more receiving yards than rushing yards in five of his six starts this year, highlighting a peculiar start to his game logs. Fantasy managers could care less how their workhorse gets his numbers so long as the overall production is elite, as it has been all season. McCaffrey will likely be asked to continue shouldering the load for the 49ers' offense against the Falcons on Sunday Night Football in Week 7.

Jeanty rushed 23 times for 75 yards and a touchdown while bringing in two of four targets for 11 yards in Sunday's 20-10 victory over the Titans.

Jeanty ground out a solid fantasy day by scoring his third rushing touchdown of the year on a season-high 23 carries. Veteran backup Raheem Mostert (five carries) was the only other rusher to record a touch in the win, highlighting Jeanty's stranglehold on the every-down role out of Las Vegas' backfield. The sixth overall pick from this year's draft has generated 497 combined yards from scrimmage with five total touchdowns through six starts in 2025. Jeanty's offensive involvement has increased with an average of 22.3 touches over the Raiders' last three contests. Fantasy managers can start the Boise State product with confidence for next Sunday's road tilt against the Chiefs.

Laube (hamstring) is questionable to return to Las Vegas' matchup versus the Titans on Sunday.

Laube left the field during the second half, and the severity of his injury is currently unclear. With Zamir White (coach's decision) inactive, Ashton Jeanty and Raheem Mostert would be the only healthy running backs on the team if Laube is unable to return.