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Matt Breida RB | SF
49ers' Matt Breida: Ready to face Jags
Breida (knee) isn't listed on the final injury report for Sunday's game against the Jaguars, Nick Wagoner of ESPN.com reports.
The 49ers have expanded Breida's role since Jimmy Garoppolo took over at quarterback, giving the rookie 29 carries the past three weeks. It will nonetheless be difficult to rely on any piece of the San Francisco offense, as the Jaguars have surrendered only 14 passing touchdowns and six rushing touchdowns all season.
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Kerwynn Williams RB | KC
Cardinals' Kerwynn Williams: Questionable for Week 16
Williams (quadriceps/ribs) is listed as questionable for Sunday's contest against the Giants, Darren Urban of the Cardinals' official site reports.
Sidelined the first two practices of Week 16 prep, Williams was seen running hard on a side field Friday with a member of the Cardinals' training staff, according to Kent Somers of The Arizona Republic. Once the session was closed to the media, Williams fit in enough reps otherwise to be termed a limited participant. While his status could come down to the wire, he has a friendly matchup on tap versus a Giants defense that has allowed 117.9 rushing yards per game and six touchdowns on the ground to running backs over the last seven games.
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Joe Mixon RB | HOU
Bengals' Joe Mixon: Doesn't carry a Week 16 injury designation
Mixon (concussion) does not carry an injury designation for Sunday's game against the Lions.
Mixon practiced fully all week and with no injury designation attached to his Week 16 status, he's on track to be back in the lineup this weekend. Prior to being forced out of action early in Week 13, Mixon had hit the 20-carry mark in back-to-back outings. In his return to action Sunday, look for him to reclaim the Bengals' lead back role, with Giovani Bernard thus ticketed for change-of-pace duty in the Bengals offense.
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Austin Ekeler RB | WAS
Chargers' Austin Ekeler: Questionable for Sunday
Ekeler (hand) is listed as questionable for Sunday's road game against the Jets.
If Ekeler does take the field Week 16, a large club will be protecting the broken ring finger on his left hand. As such, his pass-catching viability is more or less not an option, making him a candidate to receive the occasional carry or two behind Melvin Gordon. More than likely, though, Ekeler will uphold his status as a gunner on the punt team. The preceding is assuming he bypasses his status as a game-time decision and avoids the inactive list Sunday.
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Kerwynn Williams RB | KC
Cardinals' Kerwynn Williams: Back at practice
Williams (quadriceps) appears to be practicing Friday, Darren Urban of the Cardinals' official site reports.
With Williams absent from the prior two practices, it appeared the Cardinals might need to lean on Elijhaa Penny as their lead runner for Sunday's game against the Giants. Williams' return to practice Friday at least gives him a shot to play, though it's still quite possible he's no better than a game-time decision. Another update will be available Friday afternoon when the Cardinals release their final injury report.
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Damien Williams RB | ARI
Dolphins' Damien Williams: Listed as doubtful for Sunday's game
Williams (shoulder) is doubtful for Sunday's game against the Chiefs, Adam H. Beasley of the Miami Herald reports.
Williams' absence of late has led to Kenyan Drake seeing added work in the Miami backfield, an assignment that Drake has handled well. Assuming Williams is inactive Sunday, Senorise Perry and De'Veon Smith will be on hand to back up Drake.
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Samaje Perine RB | CIN
Redskins' Samaje Perine: Questionable after missing practice
Perine (groin) is listed as questionable for Sunday's game against the Broncos, John Keim of ESPN.com reports.
Perine and LeShun Daniels (broken hand) both suffered injuries Thursday, leaving Kapri Bibbs as the lone running back available for Friday's practice. With Daniels out for the season and Perine seemingly on the wrong side of the 'questionable' tag, the Redskins figure to promote Dare Ogunbowale from the practice squad before Sunday. Should Perine end up missing the game, Bibbs might be asked to handle a three-down role, albeit against a stingy Denver defense.
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LeShun Daniels RB | NE
Redskins' LeShun Daniels: Out with broken hand
Daniels fractured his hand during Thursday's practice and will miss the rest of the season, John Keim of ESPN.com reports.
With starting running back Samaje Perine listed as questionable with a groin injury, Daniels might have landed in a key role for Sunday's game against the Broncos if he hadn't injured his hand. The undrafted rookie has plenty of time to get healthy for the start of the offseason program, but there's no guarantee the Redskins even keep him around that long. The team already has four running backs on injured reserve, led by Chris Thompson (leg) and Rob Kelley (ankle).
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Samaje Perine RB | CIN
Redskins' Samaje Perine: Not practicing Friday
Perine (groin) and teammate LeShun Daniels (illness) both missed Friday's practice, John Keim of ESPN.com reports.
Perine injured his groin Thursday and wasn't able to finish practice. His continued absence Friday suggests he's in serious danger of missing Sunday's game against the Broncos, potentially leaving Kapri Bibbs as the Week 16 starter. With Daniels also absent, Bibbs was the only running back on the field at Friday's practice.
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Cordarrelle Patterson RB | PIT
Raiders' Cordarrelle Patterson: Limited in practice Thursday
Patterson (hip) was limited at Thursday's practice, Vic Tafur of The Athletic reports.
Patterson and the Raiders don't play until Monday night, so his practice regimen over the next couple of days will give a better picture of his game status. He's currently leading the league in yards per kick return with 28.3, so Oakland's special teams would take a hit if he were to sit against the Eagles. Moreover, in the event that Amari Cooper (ankle) is limited or out for the team's Week 16 contest, Patterson's workload in the passing game could increase. With Cooper sidelined in Week 15, Patterson was on the field for 44 (out of a possible 66) snaps on offense against the Cowboys.