Mack won't play Thursday in the Colts' preseason opener versus the Bills, Joel A. Erickson of The Indianapolis Star reports.
The Colts are unsurprisingly keeping several key starters out of the first preseason game. Since Mack enters 2019 with his role as the Colts' lead back already secure, there's a good chance that he only plays a few series throughout the entire preseason slate. Coach Frank Reich has said that Nyheim Hines will retain a role on obvious passing downs, so Mack won't necessarily be in store for a major uptick in his workload this season.