NFL Player News

Barkley (ankle) said Thursday that there's "no doubt" in his mind he can handle a full workload Sunday versus the Cardinals, Darryl Slater of The Newark Star-Ledger reports.

Barkley's comments were made after he managed another full practice Thursday, his second in as many days. Despite the positive development, the Giants still may give him a game-day designation upon the release of Friday's injury report. Barkley aside, the Giants' backfield seems to be getting healthier, as Wayne Gallman practiced fully Thursday as he works his way through the concussion protocol. Ultimately, Barkley's workload this weekend may be contingent on which of the team's running backs are active.

The Bengals waived Perine on Thursday.

Perine appeared in all six contests for Cincinnati this season, contributing on special teams during that stretch. Defensive end Anthony Zettel will take his spot on the 53-man roster.

Drake could be traded before the deadline if the right offer presents itself, Ian Rapoport of NFL Network reports.

Drake is set to become an unrestricted free agent in 2020, and it doesn't appear as if he and the team have been in talks regarding a potential contract extension. With the winless Dolphins clearly setting up for the 2020 season and beyond, it might be wise for them to deal the running back and accumulate another asset in the form of a draft pick. The team has already had trade conversations with potential suitors, and Drake has expressed openness to being moved.

Newsome (undisclosed) was released off the Chargers' practice squad injured list with an injury settlement Wednesday, per the NFL's official transaction log.

Newsome landed on the practice squad injured list Tuesday and didn't have to wait long before making his way to free agency. The 25-year-old is free to sign elsewhere once healthy.

Gore signed with the Chargers' practice squad Wednesday.

Gore spent training camp with the Chargers and rushed 12 times for 64 yards and one touchdown in the preseason. The rookie running back now finds himself back in the organization while Justin Jackson battles a calf issue.

Penny (hamstring) wasn't listed on Wednesday's injury report, John Boyle of the Seahawks' official site reports.

Coming off a third absence in a four-game stretch, Penny finally appears to be healthy and ready to get Seattle's backfield back to full strength. It remains to be seen how many reps he'll handle on a weekly basis, though, as Chris Carson has averaged 27.3 touches for 142.3 yards from scrimmage while scoring two touchdowns over the last three contests.

Mostert missed Wednesday's practice due to a knee injury, Nick Wagoner of ESPN.com reports.

The extent of the knee injury isn't known, but coach Kyle Shanahan termed it a "sprain" or "strain," per Matt Maiocco of NBC Sports Bay Area. With Mostert's status in question for Sunday's contest at Washington, the door may be open for Jeff Wilson to rejoin the 49ers' running back rotation alongside Matt Breida and Tevin Coleman.

Kamara (ankle/knee) did not practice Wednesday, Amie Just of The New Orleans Times-Picayune reports.

Kamara suffered a knee injury Week 6 versus the Jaguars and came into the contest dealing with a high ankle issue, per Tom Pelissero of NFL Network. The star running back has expressed some optimism that he'll be available Sunday against the Bears, but he'll almost certainly need to practice in some capacity Thursday and/or Friday for any chance of taking the field Week 7. In the event that Kamara is forced to miss any time, Latavius Murray would likely draw the start for New Orleans. The team also opted to sign Zach Zenner as a reserve option Wednesday.

Walton was a limited participant in Wednesday's practice due to a thumb injury, Safid Deen of the South Florida Sun Sentinel reports.

Walton likely picked up the injury at some point during the Week 6 loss to the Redskins, during which he accrued a career-high 75 yards on 11 touches. It's encouraging that he wasn't held out of practice entirely, and Walton will have two opportunities to upgrade to a full practice before Sunday's game against Buffalo.

Zenner agreed to a contract with the Saints on Wednesday, Ian Rapoport of NFL Network reports.

For the second week in a row, Alvin Kamara is dealing with an ankle injury, so the Saints opted to bolster the backfield by bringing in Zenner. In 36 appearances across four seasons with the Lions, Zenner averaged 3.9 yards per carry and hauled in 27 of 37 targets.