NFL Player News

Conner ran for 10 yards on five carries and caught one of two targets for six yards Thursday in Pittsburgh's 21-7 loss to Cleveland before departing in the first half after aggravating a right shoulder injury.

Returning after missing the last two games with an AC joint sprain in his shoulder, Conner struggled to find room to run, with seven of his 10 yards coming on one carry. He re-injured the shoulder in the second quarter and was initially labeled questionable to return before being ruled out for the remainder of the contest. With 10 days before Pittsburgh's next outing Week 12 versus the Bengals, fantasy owners will need to take a wait-and-see approach with regard to Conner's availability for that matchup. Cincinnati has surrendered a league-high 173.0 yards per game on the ground to date.

Chubb rushed 27 times for 92 yards in the Browns' 21-7 win over the Steelers on Thursday. He also failed to haul in his only target.

Any doubts about whether Kareem Hunt would eat into Chubb's lead-back workload were put to rest for at least one more game, as the latter logged a season-high workload. Chubb frequently found running room at a premium against a stingy Steelers front, but he did enough to help keep the chains moving and crossed the 90-yard threshold for the sixth time this season. While Hunt's role figures to continue expanding over the season's remaining games, Chubb will head into a highly favorable Week 12 matchup against the Dolphins a week from Sunday as the top backfield option for Cleveland.

Conner was removed from Thursday's game against the Browns to be evaluated for a shoulder injury.

The 24-year-old missed the previous two games with an AC joint sprain in his right shoulder but practiced fully this week, though he appears to have aggravated the injury during the first half Thursday. Conner was initially questionable to return but has since been ruled out. Jaylen Samuels and Trey Edmunds should handle backfield work for the Steelers in his absence.

Mostert (knee) was listed as a limited practice participant Thursday, Nick Wagoner of ESPN.com reports.

Mostert is nearly one month removed from injuring his knee, and while the issue has impacted his practice reps at times, he's suited up in each of the 49ers' past four games. During that span, he's racked up 17 touches for 93 yards from scrimmage and one rushing TD. With Matt Breida expected to miss the next 1-to-2 games due to a low-ankle sprain, a more consistent role may be on tap for Mostert in the short term.

Edmonds (hamstring) didn't practice Thursday, Darren Urban of the Cardinals' official site reports.

Yet again, Edmonds was listed as a DNP on the team's injury report, but in the part of Thursday's session open to the media, Edmonds was spotted working on the side, per Urban. Until he takes part in practice, Edmonds won't be a candidate to return to action, leaving him in danger of missing his third consecutive game Sunday in San Francisco. In that reality, Kenyan Drake and David Johnson will share the team's Week 11 backfield duties.

Montgomery (ankle) didn't practice Thursday.

Montgomery made a surprise appearance on the Bears' first Week 11 injury report as a limited participant. The reason become clear Thursday, when coach Matt Nagy relayed Montgomery "lightly" rolled his ankle at Wednesday's session, per Rich Campbell of the Chicago Tribune. As a result, Montgomery's lack of reps Thursday is concerning, giving him just one more chance to get in some work before the weekend. If he's limited or even absent Sunday against the Rams in L.A., Tarik Cohen and Ryan Nall are next up for work out of the Bears' backfield.

Jacobs (shoulder) remained limited at practice Thursday, Paul Gutierrez of ESPN.com reports.

We expect Jacobs to be a go Sunday against the Bengals, but he'll probably have to log a full practice Friday to approach the contest minus a Week 11 injury designation.

Breida (ankle) wasn't on the field for Thursday's practice, Matt Barrows of The Athletic reports.

Ian Rapoport of NFL Network reported that Breida would likely be sidelined for 1-to-2 weeks after aggravating a low-ankle sprain in Monday's loss to the Seahawks, so it shouldn't come as much of a surprise that he's been withheld from both of the 49ers' first two practices of Week 11. With Breida trending toward an inactive status this weekend versus Arizona, Tevin Coleman -- who was also absent from Thursday's practice due to a non-injury-related matter -- is expected to take on a more pronounced role in the San Francisco backfield.

Wilkins (ankle) was not spotted at the portion of Thursday's practice open to the media, Kevin Bowen of 107.5 The Fan Indianapolis reports.

Wilkins appears on track for a "DNP" designation on Thursday's practice report, putting his chances of suiting up versus the Jaguars on Sunday in legitimate jeopardy. He hasn't practiced in any capacity since suffering an ankle injury Week 10 versus the Dolphins. Jonathan Williams would slot in as Indianapolis' No. 3 running back if Wilkins were forced to miss any time.

McCaffrey (foot) practiced fully Thursday, Brendan Marks of The Charlotte Observer reports.

McCaffrey has had limitations on his practice reps for three consecutive weeks at this point, but they were lifted on each occasion. As a result, his foot issue won't impact his availability for the Panthers' Week 11 divisional matchup with the Falcons, who have conceded 124.9 yards from scrimmage per game and nine touchdowns to running backs in nine contests this season.