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Jose Butto SP | SF
Giants' Jose Butto: Dealing with arm tightness
Butto was removed during the eighth inning of the Giants' 7-1 loss to the Padres on Wednesday due to right arm tightness, Justice delos Santos of The San Jose Mercury News reports.
Butto was brought in for the eighth to keep the Giants' deficit at two runs, but he recorded just one out while allowing four runs on three hits and four walks, tossing 28 pitches (eight strikes) before being pulled. The Giants should have an update over the next couple of days once Butto undergoes some tests on his arm.
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Zac Gallen SP | ARI
Diamondbacks' Zac Gallen: Silences Tigers in first win
Gallen (1-1) notched the win Wednesday against the Tigers, allowing no runs on four hits and no walks in six innings. He struck out two.
Two of the hits allowed went for extra bases, but Gallen was still able to keep Detroit out of the scoring column Wednesday. Although right-hander wasn't dominant, he tossed 58 of his 88 pitches for strikes and bounced back in a big way after allowing four runs in four innings during his season debut. Gallen is set for a tough matchup on paper versus the Mets in his next scheduled start, though New York has stumbled out of the gates with .648 OPS as a team through six games.
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Tarik Skubal SP | LAD
Tigers' Tarik Skubal: Tough-luck loss Wednesday
Skubal (0-1) took the loss Wednesday against the Diamondbacks, allowing one run on six hits and no walks in seven innings. He struck out three.
The All-Star left-hander certainly wasn't deserving of the loss, but the Tigers were shut out Wednesday. Skubal had the Arizona bats off balance throughout the outing, inducing 10 groundouts while pouring in 60 of his 87 pitches for strikes, but Corbin Carroll managed to take Skubal deep in the first innings for the game's lone run. Skubal has permitted a single run on the campaign to go with a pristine 9:0 K:BB through 13 innings so far, and he'll look to keep dealing his next time out versus the Twins in Minnesota.
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Blake Snell SP | LAD
Dodgers' Blake Snell: Close to facing hitters
Manager Dave Roberts told reporters Wednesday that Snell (shoulder) will "likely" face hitters once the Dodgers return to Los Angeles from their upcoming six-game road trip, David Vassegh of AM 570 LA Sports reports.
Snell was limited to bullpen sessions during spring training due to left shoulder fatigue, prompting his placement on the 15-day injured list to open the season. He continues to progress in his recovery, and it looks like he'll start to face live hitters once the Dodgers return from their upcoming road trip that will conclude next Wednesday. Roberts noted to reporters that Snell is on track to make his 2026 debut at the end of May.
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Matthew Liberatore SP | STL
Cardinals' Matthew Liberatore: Logs quality start Wednesday
Liberatore did not factor into the decision Wednesday against the Mets, allowing a run on three hits and a walk over six innings. He struck out two.
Liberatore was impressive Wednesday, holding the Mets without a hit until the fifth inning before eventually giving up a lone run on a Juan Soto homer with two outs in the sixth for his first quality start of 2026. Through two starts, the 26-year-old Liberatore has given up just two runs on 10 hits and three walks while striking out four over 11 innings. The left-hander is tentatively in line for a road matchup with the Nationals his next time out.
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Freddy Peralta SP | TB
Mets' Freddy Peralta: Sharp in no-decision
Peralta (1-0) did not factor into the decision Wednesday against the Cardinals, allowing a run on three hits and two walks across 5.1 innings. He struck out seven.
Peralta pitched well Wednesday, blanking St. Louis through his first five innings before he was ultimately charged for a run in the sixth in an eventual 2-1, extra-innings defeat. Through his first two starts with the Mets, Peralta's given up five runs on nine hits and two walks over 10.1 innings while striking out seven in both outings. He's currently slated for a home matchup with the Diamondbacks his next time out.
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Michael Burrows SP | HOU
Astros' Mike Burrows: Earns first win
Burrows (1-1) earned the win Wednesday over the Red Sox, allowing two runs on five hits and three walks over five innings. He struck out six.
Burrows had to contend with traffic Wednesday, though he managed to hold Boston to a pair of runs en route to his first win with the Astros. It was a nice rebound effort overall from Burrows after he gave up five runs on nine hits in his first start against the Angels. The right-hander is currently slated to face the Rockies at Coors Field his next time out.
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Drew Rasmussen SP | TB
Rays' Drew Rasmussen: Fans eight in no-decision
Rasmussen allowed two runs (one earned) on two hits and a walk across five innings Wednesday against the Brewers. He struck out eight.
Rasmussen matched his 2025 season high with eight strikeouts Wednesday. The right-hander has been sharp in two starts to open the 2026 campaign, allowing just two earned runs on six hits across 10 innings. Rasmussen will look to keep it going in his next outing, tentatively scheduled to come next week at home against the Cubs.
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Yusei Kikuchi SP | LAA
Angels' Yusei Kikuchi: Crumbles in third inning Wednesday
Kikuchi (0-1) took the loss Wednesday against the Cubs, allowing five runs on six hits and four walks in 5.1 innings. He struck out five.
Although Kikuchi managed to keep the ball in the yard, the four free passes he piled up came back to haunt him a bit. Two of which came in the third inning, when the Cubs strung together five hits and tagged the left-hander for each of his five runs allowed. Kikuchi's next start is scheduled for next week at home against Atlanta, and he'll be aiming to get back on track after yielding seven runs across his first 9.2 innings of 2026.
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Jacob Misiorowski SP | MIL
Brewers' Jacob Misiorowski: Strikes out seven in no-decision
Misiorowski did not factor into the decision Wednesday against the Rays, allowing two runs on four hits and two walks across six innings. He struck out seven.
It was another strong effort from Misiorowski, with the lone damage coming on Yandy Diaz's two-run homer in the third inning. Through two starts, the right-hander has allowed three runs on six hits and five walks while punching out 18 over 11 innings. Misiorowski has also given up a pair of homers this year, with the long balls and walks being his only areas of concern at the moment. He is currently slated to face the Red Sox on the road his next time out.