Horton was removed from his start in the first game of Monday's doubleheader with the Brewers midway through the third inning due to an apparent blister on his pitching hand, Bruce Levine of 670TheScore.com reports. He struck out three batters and gave up one run on four hits and one walk over 2.2 frames prior to departing the contest.

The Cubs will likely provide clarity later Monday regarding whether Horton was battling a blister or some other kind of health concern, but the rookie was pulled from the contest after he was visited twice on the mound by Craig Counsell and a team trainer and on an another occasion by pitching coach Tommy Hottovy. Prior to Monday's twin bill, Horton had been the Cubs' top performing starter since the All-Star break, having posted a microscopic 0.32 ERA and 0.71 WHIP in 28.1 innings over his last five starts. After exiting with a 1-0 deficit, Horton will be on the hook for his fourth loss of the season if the Cubs are unable to tie the game or take the lead at any point in the remainder of the contest.

Reds manager Terry Francona said in an interview on MLB Network Radio on SiriusXM that Burns (elbow) will resume a throwing program Monday.

Burns landed on the 15-day injured list Friday after being diagnosed with a Grade 1 right flexor strain, but the fact that the rookie has already been cleared to throw backs up the Reds' optimism that the righty is not facing an extended absence. When Burns returns from the IL, he could be deployed in relief, as the Reds have a bevy of other rotation options and also want to manage the 22-year-old's workload.

Tong gave up three hits and two walks over 5.2 scoreless innings for Triple-A Syracuse on Sunday. He struck out nine.

The MiLB strikeout leader kept on racking up whiffs in his Triple-A debut. Tong has a stunning 1.59 ERA, 0.92 WHIP and 171:46 K:BB through 107.2 innings on the season between Double-A and Triple-A, and while the fact that the 2022 seventh-round pick isn't on the 40-man roster might delay his big-league debut until 2026, he appears to have little left to prove in the minors.

Megill (elbow) struck out nine batters over 3.1 scoreless innings in a rehab start for Double-A Binghamton on Sunday. He allowed just one hit without walking a batter.

The right-hander was simply too much for Eastern League hitters, firing 39 of 55 pitches for strikes in his second rehab appearance. Megill hasn't pitched for the Mets since June 14 due to an elbow sprain, so he'll need at least one more start in the minors before potentially being an option for the big-league rotation, and it wouldn't be a surprise if he gets two more while the team takes a look at top prospect Nolan McLean. Over five innings for Binghamton on his rehab stint, Megill hasn't given up a run while posting a 13:1 K:BB.

The Cubs optioned Assad to Triple-A Iowa on Monday, Andy Martinez of Marquee Sports Network reports.

Assad permitted five runs on 13 hits and two walks over eight innings in his two starts with the big club. He will cede his rotation spot to Jameson Taillon (calf), who will be reinstated from the 15-day injured list to make a start at some point during the Cubs' five-game series with the Brewers that opens Monday with a doubleheader.

The Brewers recalled Patrick from Triple-A Nashville on Monday.

Patrick is the Brewers' designated 27th man for Monday's doubleheader against the Cubs and will start the second game of the twin bill at Wrigley Field. The rookie right-hander was squeezed out of the Brewers rotation last month but has pitched well for the big club, posting a 3.52 ERA and 95:30 K:BB over 94.2 frames covering 18 starts and one relief outing.

Fedde did not factor in the decision during Sunday's win over the Guardians. He allowed four runs on six hits and three walks over four innings while striking out five.

Fedde worked a perfect first inning before things started to go south. He loaded the bases in the second but escaped without giving up a run. The Guardians then plated a pair of runs in each of the third and fourth frames. Fedde has now made four starts with Atlanta and has given up at least three runs while failing to complete six innings in all four. That's resulted in a 7.11 ERA, driving his season ERA to 5.52 across 120.2 innings. Fedde is currently projected for a home matchup against the Mets next weekend.

Holmes (10-6) allowed one run on five hits and a walk while striking out four over five innings to earn the win over the Mariners in Sunday's Little League Classic.

Holmes put forth a fine effort, throwing 58 of 88 pitches for strikes. He's had some trouble pitching deeper into games -- he hasn't completed six frames since his June 7 start in Colorado. The right-hander is 2-2 with 18 runs allowed (15 earned) over 27.2 innings over six starts since the All-Star break. Holmes has a 3.64 ERA, 1.34 WHIP and 105:53 K:BB over 131 innings through 25 starts this season. He's tentatively scheduled for a road matchup in Atlanta in his next start.

Sale (ribcage) struck out four and allowed one earned run on three hits and one walk over four innings in his rehab start Sunday with Triple-A Gwinnett.

Sale had another strong showing in the second outing of his rehab assignment, firing 39 of his 56 pitches for strikes while inducing six swings and misses. The southpaw will likely make one more start on the farm before returning from the 60-day injured list in the final week of August and being part of what's expected to be a six-man rotation for Atlanta heading into the final month of the season.

Triple-A Gwinnett placed Fuentes on its 7-day injured list Aug. 10 due to an unspecified injury.

Fuentes hadn't pitched for Gwinnett since Aug. 2 before the Triple-A club deactivated him a week later. Following a rough four-start run with Atlanta before being optioned July 9, Fuentes had returned to form in the minors prior to being shut down, logging a 4.08 ERA, 1.19 WHIP and 23:4 K:BB in 17.2 innings over four appearances for Gwinnett.