Vaughn is not in the lineup for Wednesday's game against the Twins.

It's the first day off this season for Vaughn, who is 3-for-19 with a home run in the first five contests. Nick Maton will start at first base and bat leadoff for the White Sox on Wednesday.

Pasquantino is not in the lineup for Tuesday's game in Milwaukee.

Pasquantino started each of the Royals' first four games of the season, although he's been limited to designated hitter duty as he comes back from a hamstring injury. MJ Melendez will be the club's DH on Tuesday, while Cavan Biggio will cover first base.

Aranda is not in the lineup for Tuesday's game against the Pirates, Ryan Bass of FanDuel Sports Network Sun reports.

Aranda has gone 5-for-9 with four doubles, an RBI and two runs in the first four games of the season but will take a seat for Tuesday's contest. Curtis Mead will receive the start at first base versus Pittsburgh righty Thomas Harrington.

Goldschmidt will start at first base and bat leadoff in Tuesday's game versus the Diamondbacks.

When Goldschmidt batted leadoff in the Yankees' second game of the season, the feeling was that it was only because the club was facing a left-hander. However, he has now remained at the top of the batting order in the two contests since then as well, and both of them have been against righties. The Yankees have scored a whopping 32 runs in two games with Goldschmidt in the leadoff spot, so manager Aaron Boone doesn't feel the need to switch things up. After hitting leadoff Opening Day, Austin Wells is batting sixth for the third game in a row.

Santana started at first base and went 2-for-4 with a double in Monday's 7-2 loss to San Diego.

Santana has started at first base and served as Cleveland's cleanup hitter for all four games thus far. He's hit safely in three of those four games, going 6-for-16 with two doubles, three runs scored and one RBI. The 38-year-old (turns 39 on April 8) is projected to have an everyday role for the Guardians.

Burger went 1-for-4 with a two-run home run in Monday's 14-3 loss to Cincinnati.

Burger's two-run shot in the ninth inning was little consolation for the Rangers, who were down 6-0 after two innings and 14-0 before they got on the scoreboard. The homer was Burger's first of the season. The first baseman has reached base safely in four of the first five games, scoring four runs and knocking in three.

Vaughn went 1-for-3 with a three-run home run in Monday's 9-0 win over the Twins.

Vaughn began the season 1-for-12 across a three-game series against the Angels, but he started the White Sox's offensive onslaught Monday when he took Chris Paddack deep for a 371-foot, three-run homer to left field in the first inning. Vaughn was one long shot shy from recording a second-straight 20-homer season last year and will aim to reach that benchmark in 2025.

Manzardo is absent from the lineup for Monday's game in San Diego.

The left-handed hitting Manzardo started each of the first three contests of the season, including one versus a southpaw, but he'll get a day off Monday against lefty Kyle Hart. Johnathan Rodriguez is getting a start at designated hitter as Manzardo rests.

Malloy will serve as the designated hitter and bat in the leadoff spot against the Mariners on Monday.

Malloy was recalled by Detroit from Triple-A Toledo on Monday, and he'll waste no time getting into his first major-league action of the season. He appeared in three games for Toledo before being called up and went 5-for-11 with two walks, one home run and five RBI.

Gonzalez started at first base and went 2-for-4 with a double, an RBI and a run scored in Monday's 8-5 loss to Baltimore.

Gonzalez made his first start of the season, filling in for Triston Casas against a lefty. Red Sox manager Alex Cora said during spring training that Casas would not be subject to a platoon, but he was on the bench with Boston facing its first lefty of the season. The decision to sit Casas may have more to do with his slow start. Including his pinch-hit appearance Monday, Casas is 1-for-17 with seven strikeouts.