Offense
| NO | Player | POS | HT | WT | DOB (AGE) | EXP | College |
|---|---|---|---|---|---|---|---|
| 10 | M. JonesMac Jones | QB | 6-3 | 220 | 9/5/1998 (28) | 6 | Alabama |
| 13 | B. PurdyBrock Purdy | QB | 6-1 | 220 | 12/27/1999 (26) | 5 | Iowa St. |
| 14 | K. RourkeKurtis Rourke | QB | 6-4 | 221 | 10/25/2000 (25) | 1 | Indiana |
| 26 | K. BlackKaelon Black | RB | 5-9 | 208 | 10/17/2001 (24) | R | Indiana |
| 29 | J. JamesJordan James | RB | 5-9 | 208 | 3/29/2004 (22) | 2 | Oregon |
| 23 | C. McCaffreyChristian McCaffrey | RB | 5-11 | 210 | 6/7/1996 (30) | 10 | Stanford |
| 44 | K. JuszczykKyle Juszczyk | FB | 6-2 | 235 | 4/23/1991 (35) | 14 | Harvard |
| 4 | J. CowingJacob Cowing | WR | 5-9 | 170 | 2/4/2001 (25) | 3 | Arizona |
| 5 | M. EvansMike Evans | WR | 6-5 | 231 | 8/21/1993 (33) | 13 | Texas A&M |
| 86 | K. HodgeKhadarel Hodge | WR | 6-2 | 210 | 1/3/1994 (32) | 9 | Prairie View |
| 19 | D. SamuelDeebo Samuel | WR | 6-0 | 215 | 1/15/1996 (30) | 8 | South Carolina |
| 17 | J. WatkinsJordan Watkins | WR | 5-11 | 196 | 2/15/2002 (24) | 2 | Ole Miss |
| 89 | L. FarrellLuke Farrell | TE | 6-5 | 250 | 10/14/1997 (28) | 6 | Ohio State |
| 85 | G. KittleGeorge Kittle | TE | 6-4 | 250 | 10/9/1993 (32) | 10 | Iowa |
| 9 | B. WillisBrayden Willis | TE | 6-4 | 240 | 11/11/1999 (26) | 3 | Oklahoma |
| 64 | J. BrendelJake Brendel | C | 6-4 | 299 | 9/10/1992 (34) | 9 | UCLA |
| 69 | E. Cruz Jr.Enrique Cruz Jr. | OT | 6-5 | 313 | 8/4/2003 (23) | R | Kansas |
| 76 | V. LoweVederian Lowe | OT | 6-5 | 315 | 4/17/1999 (27) | 5 | Illinois |
| 68 | C. McKivitzColton McKivitz | OT | 6-6 | 301 | 8/9/1996 (30) | 7 | West Virginia |
| 77 | D. PuniDominick Puni | OT | 6-5 | 313 | 2/24/2000 (26) | 3 | Kansas |
| 71 | T. WilliamsTrent Williams | OT | 6-5 | 320 | 7/19/1988 (38) | 17 | Oklahoma |
| 74 | C. WillisCarver Willis | OT | 6-5 | 303 | 4/20/2002 (24) | R | Washington |
| 75 | C. ColbyConnor Colby | G | 6-5 | 309 | 1/16/2003 (23) | 2 | Iowa |
| 54 | J. PattersonJarrett Patterson | G | 6-4 | 310 | 9/1/1999 (27) | 4 | Notre Dame |
Defense
| NO | Player | POS | HT | WT | DOB (AGE) | EXP | College |
|---|---|---|---|---|---|---|---|
| 97 | N. BosaNick Bosa | DE | 6-4 | 266 | 10/23/1997 (28) | 8 | Ohio State |
| 94 | R. HeightRomello Height | DE | 6-3 | 239 | 4/13/2001 (25) | R | Texas Tech |
| 56 | K. WhiteKeion White | DE | 6-5 | 285 | 1/20/1999 (27) | 4 | Georgia Tech |
| 90 | K. GivensKevin Givens | DT | 6-1 | 285 | 3/1/1997 (29) | 7 | Penn State |
| 93 | G. HaltonGracen Halton | DT | 6-3 | 293 | 1/27/2004 (22) | R | Oklahoma |
| 91 | N. JonesNaquan Jones | DT | 6-3 | 313 | 2/5/1998 (28) | 6 | Michigan St. |
| 92 | O. OdighizuwaOsa Odighizuwa | DT | 6-2 | 280 | 8/13/1998 (28) | 6 | UCLA |
| 96 | J. Thompson Jr.James Thompson Jr. | DT | 6-6 | 308 | 8/29/2002 (24) | R | Illinois |
| 55 | S. ValdezSebastian Valdez | DT | 6-3 | 301 | 8/1/2002 (24) | 1 | Washington |
| — | K. KareemKhalid Kareem | DL | 6-4 | 255 | 4/28/1998 (28) | 4 | Notre Dame |
| 54 | F. WarnerFred Warner | MLB | 6-3 | 230 | 11/19/1996 (29) | 9 | BYU |
| 48 | T. BethuneTatum Bethune | LB | 6-0 | 230 | 2/19/2001 (25) | 3 | Florida State |
| 53 | J. DuggerJaden Dugger | LB | 6-5 | 242 | 2/26/2004 (22) | R | — |
| 51 | L. GiffordLuke Gifford | LB | 6-3 | 242 | 8/28/1995 (31) | 8 | Nebraska |
| 57 | D. GreenlawDre Greenlaw | LB | 6-0 | 230 | 5/25/1997 (29) | 8 | Arkansas |
| 49 | G. WallowGarret Wallow | LB | 6-2 | 230 | 1/25/1999 (27) | 6 | TCU |
| 0 | R. GreenRenardo Green | CB | 6-0 | 186 | 11/9/2000 (25) | 3 | Florida State |
| 25 | J. JonesJack Jones | CB | 5-11 | 175 | 12/20/1997 (28) | 5 | Arizona St. |
| 2 | D. LenoirDeommodore Lenoir | CB | 5-10 | 200 | 10/6/1999 (26) | 6 | Oregon |
| 35 | E. PrysockEphesians Prysock | CB | 6-4 | 195 | 2/28/2003 (23) | R | Washington |
| 20 | U. StoutUpton Stout | CB | 5-9 | 182 | 1/9/2002 (24) | 2 | W. Kentucky |
| 33 | S. NealSiran Neal | DB | 6-0 | 206 | 8/4/1994 (32) | 9 | Jacksonville St. |
| 27 | J. BrownJi'Ayir Brown | SAF | 5-11 | 202 | 1/25/2000 (26) | 4 | Penn State |
| 24 | A. DavisAshtyn Davis | SAF | 6-1 | 205 | 10/10/1996 (29) | 7 | California |
| 6 | M. MustaphaMalik Mustapha | SAF | 5-10 | 206 | 6/25/2002 (24) | 3 | Wake Forest |
| 36 | M. SigleMarques Sigle | SAF | 5-11 | 199 | 7/18/2002 (24) | 2 | Kansas State |
Special Teams
| NO | Player | POS | HT | WT | DOB (AGE) | EXP | College |
|---|---|---|---|---|---|---|---|
| 18 | E. PineiroEddy Pineiro | K | 5-11 | 190 | 9/13/1995 (31) | 9 | Florida |
| 15 | C. WaitmanCorliss Waitman | P | 6-2 | 210 | 7/21/1995 (31) | 4 | South Alabama |
| 46 | J. WeeksJon Weeks | LS | 5-10 | 242 | 2/17/1986 (40) | 17 | Baylor |