NFL Week 11 odds, predictions, expert picks: Can Lions take down Eagles? Will Broncos survive Chiefs?
CBS Sports and SportsLine break down every single Week 11 matchup
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8 min read
Another week, another round of must-see matchups is on tap across the NFL. Week 10 brought plenty of stunners, including the Miami Dolphins routing the rival Buffalo Bills and Los Angeles Chargers blanking the Pittsburgh Steelers in prime time. Now we've got another slate full of intriguing action in Week 11.
We collected all the best picks and gambling content from CBS Sports and SportsLine and put them in one place. That way you can get picks against the spread from our CBS Sports experts as well as additional feature content for each game, including plays from top SportsLine experts and the SportsLine Projection Model, best bets from our staff, survivor picks and more. Let's jump in.
NFL odds via DraftKings Sportsbook (unless otherwise noted). Bet NFL Week 11 games at DraftKings Sportsbook, where new users get $300 in bonus bets and three free months of NBA League Pass.
Commanders at Dolphins
Sunday, 9:30 a.m. ET on NFL Network | Stream: Fubo (try for free)
Commanders +2.5: "The Dolphins are coming off their biggest win of the season, [but] this is still one of the worst teams in the NFL [that] could be due for a letdown, particularly as they head ... to Spain for this matchup. It's hard to imagine they'll play with the same vigor. As for the Commanders, they'll again be without Jayden Daniels and Terry McLaurin, but I think Marcus Mariota is a backup quarterback capable of leading his team to an upset win, particularly against a defense that is giving up 25.6 points per game (ninth-highest in the NFL)." -- CBS Sports NFL writer Tyler Sullivan on why he likes Washington to steal this matchup.
Panthers at Falcons
Sunday, 1 p.m. ET on Fox | Stream: Fubo (try for free)
Falcons -3.5: "These two have had weird, inconsistent seasons, but this is basically a game to help keep their playoff chances alive. The Panthers have trouble throwing the football, which will be a challenge here. The Panthers need more from Bryce Young, but I don't think they get it." -- CBS Sports senior NFL columnist Pete Prisco on why he likes Atlanta to claim a 24-17 win.
Buccaneers at Bills
Sunday, 1 p.m. ET on CBS | Stream on Paramount+
Buccaneers +5.5: "The Bills have lost three out of their last five since starting 4-0, including that eye-popping loss to the Miami Dolphins on Sunday. I have major concerns about this defense, which ranks bottom three in the NFL in opponent rushing yards per game (147.6), opponent yards per rush (5.5) and opponent rushing touchdowns (14). The Buccaneers are 17-8 ATS as an underdog since Baker Mayfield joined the team in 2023, which is the best mark in the NFL. The Bills, on the other hand, are 2-5 ATS as a favorite this season." -- CBS Sports writer Jordan Dajani on why he likes Buffalo to win, albeit narrowly.
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|---|---|---|---|---|---|---|---|---|
| Buccaneers at Bills (-5.5) |  |  | | | | | | |
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Texans at Titans
Sunday, 1 p.m. ET on Fox | Stream: Fubo (try for free)
Each week, the SportsLine Projection Model scours every game to forecast top bets for NFL parlays, including a five-leg wager that could produce a payout of around 24-1. Is it possible the Texans should be featured in this week's parlay, especially after Davis Mills helped guide a comeback victory over the rival Jaguars? Check out SportsLine's full breakdown of Week 11 picks right here.
Bears at Vikings
Sunday, 1 p.m. ET on Fox | Stream: Fubo (try for free)
Bears +3.5: The SportsLine simulation model, which projects every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. We can tell you one of the model's strongest picks for this week is that the Bears cover against their division rivals, with Chicago prevailing against the spread more than 50% of the time. Why else might you back Caleb Williams and Co., who've won six of their last seven? Check out SportsLine's full preview of the matchup right here.
Packers at Giants
Sunday, 1 p.m. ET on Fox | Stream: Fubo (try for free)
SportsLine expert R.J. White is 718-623-37 and up more than 32 units on ATS picks over the last eight years making NFL projections. While survivor pools don't involve picking against the spread, White applies his extensive knowledge of the league to recommend best bets for the format. Could Green Bay be a safe Week 11 choice, given the Giants' quarterback change amid Jaxson Dart's injury? Or does R.J. like a few other favorites as better options? Check out his full analysis right here.
Bengals at Steelers
Sunday, 1 p.m. ET on CBS | Stream on Paramount+
Bengals +5.5: "Through 10 weeks, the Steelers have given up the most passing yards per game in the NFL (269.4). To put that in perspective, the Bengals are only giving up 260.1. ... This feels like a game where Joe Flacco is going to go off again; the only question is whether the Bengals defense will be able to slow down the Steelers at all. ... The AFC North is the only division in the NFL where none of the teams have reached six wins yet and I'll say it stays that way with the Bengals pulling off the upset and getting the season sweep of Pittsburgh." -- CBS Sports NFL writer John Breech on why he likes the Bengals to prevail.
Chargers at Jaguars
Sunday, 1 p.m. ET on CBS | Stream on Paramount+
Chargers -3: "This is a long trip for the Chargers after a Sunday night game, but they are getting a Jaguars team coming off a demoralizing loss last week to the Texans. How will they respond? I look for Justin Herbert to have a good day against a team that doesn't rush the passer or excel in coverage." -- CBS Sports senior NFL columnist Pete Prisco on why he likes Los Angeles to secure a 27-20 victory on the road.
Seahawks at Rams
Sunday, 4:05 p.m. ET on Fox | Stream: Fubo (try for free)
Seahawks +3: "This feels like a potential NFC championship preview between two rivals, who are both 7-2 and knotted atop the NFC West. ... But there can only be one winner, and I'm planting my flag with Seattle. I certainly love taking them with the points, slipping a field goal in my pocket in a game where the margin is razor-thin. That said, I also like them to pull off the upset. The Seahawks have shown us this season that road environments don't faze them, coming into Week 11 with a perfect 4-0 ATS and SU road record. They are also extremely balanced on both sides of the ball when they have their foot on the gas." -- CBS Sports NFL writer Tyler Sullivan on why he likes Seattle to escape L.A. with a 24-21 win over Matthew Stafford and Co.
49ers at Cardinals
Sunday, 4:05 p.m. ET on Fox | Stream: Fubo (try for free)
Cardinals +3: The SportsLine Projection Model can be used to attack the survivor pool format, which calls for picking one team to win each week but never using the same team twice. This week, the model is shying away from picking the 49ers (6-4). Arizona has won two of its last three meetings with San Francisco, and quarterback Jacoby Brissett, a career backup, has done an admirable job in replacing the injured Kyler Murray. Despite opening as the 3-point home underdog, the model projects Arizona covering in more than 50% of simulations, making the 49ers a team to fade. Check out the full breakdown right here.
Ravens at Browns
Sunday, 4:25 p.m. ET on CBS | Stream on Paramount+
The SportsLine projection model entered Week 10 on a sizzling 47-29 run on top-rated picks dating back to 2024. So where does the model lean in this AFC North clash? With Lamar Jackson back in full swing for Baltimore, are the Ravens poised to deliver as more than touchdown favorites against Cleveland, even on the road? Check out SportsLine's expert prediction right here.
Chiefs at Broncos
Sunday, 4:25 p.m. ET on CBS | Stream on Paramount+
The Chiefs may be desperate to keep pace with Denver, plus the rival Los Angeles Chargers, in the AFC West race. But SportsLine's Projection Model envisions a slow day for Patrick Mahomes and the Kansas City offense, specifically in regards to Mahomes' top target: Chiefs tight end Travis Kelce, a 10-time Pro Bowler who ranks as the TE5 in Fantasy this year, may not warrant a spot in Week 11 lineups; the model suggests he's a player to fade this week even though he had the second most-positional Fantasy points from Weeks 5-9. Check out SportsLine's full preview of this divisional showdown right here.
Lions at Eagles
Sunday, 8:20 p.m. ET on NBC | Stream: Fubo (try for free)
SportsLine expert R.J. White, who also serves as Fantasy and gambling editor for CBS Sports, returned more than $3,200 to $100 players from 2017-2024. He's also got a special pulse of the Lions, going 34-21-2 (+1177) on his last 57 picks in games involving Detroit. So does he like Dan Campbell's squad to take down the reigning Super Bowl champions in Philadelphia? Or is he eyeing the Eagles for a fourth straight win? Check out White's full expert breakdown of this matchup right here.
Cowboys at Raiders
Monday, 8:15 p.m. ET on ABC, ESPN | Stream: Fubo (try for free)
SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. SportsLine's AI has nailed more than 2,000 4.5- and 5-star prop picks since the start of the 2023 season. After analyzing every game in Week 11, the AI says the Cowboys (-3.5) cover comfortably against the Raiders, who have lost three in a row. The model rates the Cowboys as an A+ pick on the money line and also predicts a 29-21 win on average. Check out the full breakdown right here.
