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Derrick Henry RB | BAL
Ravens' Derrick Henry: Over 100 rushing yards with receiving TD
Henry rushed 24 times for 102 yards while catching one of two targets for an 18-yard touchdown in Sunday's 30-23 overtime win over the Falcons. He also ran in a two-point conversion.
Henry unsurprisingly worked as the focal point of Baltimore's offense in the absence of Lamar Jackson (ankle). The star running back pulled the Ravens within two points with his 18-yard touchdown catch in the third quarter. Baltimore's two-point conversion attempt after that touchdown failed, but Henry took matters into his own hands to convert a game-tying two-point conversion out of the wildcat formation with 40 seconds left in the fourth quarter. He then tacked on 32 rushing yards on Baltimore's touchdown drive in OT to top the century mark on the ground for the first time since Week 1. Henry has opened his 11th NFL season with a five-game touchdown streak, producing seven rushing touchdowns and one receiving score ahead of a Week 6 trip to Cleveland.
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Tyjae Spears RB | TEN
Titans' Tyjae Spears: Nine catches in defeat
Spears rushed twice for no gain and lost a fumble while catching all nine of his targets for 28 yards during Sunday's 26-3 loss to the Texans.
Spears put the ball on the ground on his first carry of the day in the first quarter, and the fumble was recovered by Texans cornerback Jalen Pitre. The running back only had one more rush on the day, but he was able to make his mark as a pass-catcher, leading the team while reeling in a career-high nine passes. Spears has now turned 17 carries into 65 yards while catching 14 of 16 targets for 68 yards over five contests this season.
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Bijan Robinson RB | ATL
Falcons' Bijan Robinson: Posts 118 scrimmage yards in OT loss
Robinson rushed 17 times for 86 yards while catching four of seven targets for 32 yards in Sunday's 30-23 overtime loss to the Ravens.
Robinson was held without a touchdown after scoring four times over the previous two games, but he managed to top 100 scrimmage yards for the fourth time in five games. The star running back was far more effective than backup Brian Robinson, who also had four touchdowns over the previous two games but turned seven carries and one target into just 16 yards against the Ravens. Bijan has racked up 732 scrimmage yards and five total TDs heading into a Week 6 home game against the Bears. Michael Penix (ribs) was hurt late in Sunday night's loss to Baltimore, so it remains to be seen whether Penix or Tua Tagovailoa will start under center for Atlanta against Chicago.
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Xavier Hutchinson WR | HOU
Texans' Xavier Hutchinson: Four catches in win
Hutchinson caught four of five targets for 65 yards in Sunday's 26-3 win over the Titans.
Hutchinson led the team in receiving yards while his four catches were tied for second with running back Woody Marks. The wide receiver has now reeled in 16 of 31 targets for 231 yards over the first five games of the season. The Texans announced that they traded for wide receiver Marvin Harrison on Sunday, and the addition of Harrison will definitely lower Hutchinson's upside as a fantasy asset moving forward.
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Michael Penix Jr. QB | ATL
Falcons' Michael Penix: Sustains rib injury in OT loss
Penix (ribs) was listed as questionable to return in overtime of Sunday's game against the Ravens, per Tori McElhaney of the Falcons' official site, and Penix subsequently didn't return to the 30-23 overtime loss.
Penix was injured after taking a big hit on Atlanta's final possession of the fourth quarter. He came back into the game after missing one play and threw an incomplete pass to close out regulation, but Penix was unable to return for overtime. Tua Tagovailoa promptly threw an interception on Atlanta's second offensive play of OT to seal the loss for the Falcons after the Ravens scored to begin the extra session. The oft-injured Penix will try to overcome this latest setback before the Falcons host the Bears in Week 6. He completed 19 of 32 passes for 240 yards and one touchdown while rushing twice for eight yards in the loss to the Ravens.
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C.J. Henderson CB | ATL
Falcons' C.J. Henderson: Dealing with groin injury
Henderson (groin) is questionable to return to Sunday night's contest against the Ravens, Josh Kendall of The Athletic reports.
Henderson is dealing with an apparent groin injury, and his chances to return to the field before the end of Sunday's contest appear to be slim. In his absence, Aveion Terrell, Billy Bowman and Sydney Brown all stand to see an increase in opportunities in the secondary.
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Makai Lemon WR | PHI
Eagles' Makai Lemon: Reels in five passes during loss
Lemon caught five of seven targets for 43 yards during Sunday's 19-17 loss to the Jaguars.
Lemon was able to set new career highs in receptions and receiving yards Sunday, finishing second on the team in targets behind fellow wide receiver Dontayvion Wicks (8). The rookie is slowly coming into his own with Philadelphia, and he's had an opportunity to operate in a more prominent role with DeVonta Smith (hamstring) sidelined for the last two games. Lemon has now caught 15 of 22 targets for 108 yards over the first five contests of the 2026 campaign.
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Dontayvion Wicks WR | PHI
Eagles' Dontayvion Wicks: Five receptions in loss
Wicks caught five of eight targets for 63 yards during Sunday's 19-17 loss to the Jaguars.
Wicks led the team in targets, and he was able to match his season-high five catches in the defeat. The wide receiver also exceeded 60 receiving yards for the third time this season and first time since Week 2. Wicks has now caught 17 of 28 targets for 260 yards and a touchdown over his first five regular-season contests as a member of the Eagles.
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Jakobi Meyers WR | JAC
Jaguars' Jakobi Meyers: Limited production in Week 5
Meyers caught two of three targets for 37 yards during Sunday's 19-17 win against the Eagles.
Meyers was limited to 40 or fewer receiving yards for the fourth time this season, and he finished tied with running back Bhayshul Tuten for fourth on the team in targets Sunday. Meyers has solidified himself as the team's No. 2 wide receiver behind Parker Washington early in the season, but his production hasn't been that notable. Through five games, Meyers has caught 15 of 18 targets for 202 yards and two touchdowns.
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Chris Rodriguez Jr. RB | JAC
Jaguars' Chris Rodriguez: Two rushes in win
Rodriguez rushed twice for five yards and caught his only target for six yards during Sunday's 19-17 win over Philadelphia.
Rodriguez was scarcely used in Week 5, logging his fewest carries in a game this season. Starting running back Bhayshul Tuten turned 22 carries into 72 yards, and he's clearly the preferred option over Rodriguez in the backfield, regardless of circumstance. Over five games this season, Rodriguez has rushed 28 times for 113 yards and two touchdowns while catching one pass for six yards.