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Tank Bigsby RB | PHI
Eagles' Tank Bigsby: Gets into end zone in Sunday's win
Bigsby carried the ball 13 times for 33 yards and a touchdown in Sunday's 24-20 win over the Titans. He also caught both his targets for five yards.
The fourth-year RB got the Eagles on the board in the second quarter with a two-yard TD plunge, and Bigsby led the backfield in totes and rushing yards after Saquon Barkley picked up a stinger on the first play from scrimmage. Barkley was able to return after halftime, but he'll be sent for further testing and isn't guaranteed to be 100 percent for a Week 3 road trip to Chicago. If he's sidelined or has his workload scaled back, Bigsby would be poised to benefit.
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DeVonta Smith WR | PHI
Eagles' DeVonta Smith: Big day in Week 2 win
Smith caught 10 of 13 targets for 117 yards and a touchdown in Sunday's 24-20 win over the Titans.
The veteran wideout saw more than twice as many targets as any other Eagle, with Smith's biggest reception coming just before halftime on a 22-yard TD toss from Jalen Hurts. Smith is looking the part of Philly's new WR1 following the offseason departure of A.J. Brown, compiling a 13-170-1 line on 19 targets through two games. He'll look to build on those numbers in a Week 3 road trip to Chicago.
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Deshaun Watson QB | CLE
Browns' Deshaun Watson: Makes strong case in upset win
Watson completed 24 of 30 passes for 238 yards with two touchdowns and no interceptions while adding seven rushes for 22 yards in the Browns' 23-19 win over the Buccaneers on Sunday.
The proverbial vultures seemed to be surrounding Watson already after an ugly Week 1 loss to the Jaguars, but the oft-maligned veteran signal-caller preserved his starting job for the moment with Sunday's weather-delayed upset victory. Watson ran the Browns offense with a steady hand throughout the afternoon, avoiding turnovers while navigating a pair of sacks and connecting with Denzel Boston (55 yards) and Blake Whiteheart (17 yards) for his pair of touchdown passes. Watson has completed a stellar 76.9 percent of his passes and posted a 3:1 TD:INT through two games, and he'll next take on the Panthers in a Week 3 home matchup next Sunday.
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Brandon Coleman G | WAS
Commanders' Brandon Coleman: Injures finger against Dallas
Coleman exited Sunday's game against the Cowboys with a finger injury and is questionable to return.
Coleman was already filling in at left tackle for Laremy Tunsil (triceps), who is expected to miss the entire 2026 season. Josh Conerly and Andrew Wylie are the top remaining healthy tackle options for Washington.
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Will Johnson CB | ARI
Cardinals' Will Johnson: Leaves game with neck injury
Johnson (neck) is questionable to return Sunday against the Seahawks.
Given that the game is well into the fourth quarter, it would be surprising to see Johnson return. His status over the coming days will be worth monitoring ahead of the Cardinals' Week 3 road tilt against the 49ers. Kei'Trel Clark and Kalen King would be candidates to start at outside cornerback if Johnson misses time.
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Baker Mayfield QB | TB
Buccaneers' Baker Mayfield: Falls flat in revenge game
Mayfield completed 21 of 34 passes for 182 yards with one touchdown and one interception while adding four rushes for 29 yards in the Buccaneers' 23-19 loss to the Browns on Sunday.
There had been buzz surrounding Mayfield's matchup against the team that drafted him first overall in 2018, but the veteran signal-caller couldn't deliver a revenge victory. Mayfield looked surprisingly out of sorts most of the afternoon against a Browns defense that had been dominated by the Jaguars in Week 1, and after an extensive weather delay, he went just 1-for-4 for six yards once play resumed at the two-minute warning with the Buccaneers at Cleveland's 28-yard line and needing a touchdown. Mayfield added another turnover on his late first-quarter interception as well, putting him firmly in the spotlight heading into a Week 3 home date against an aggressive Vikings defense next Sunday.
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Jalen Hurts QB | PHI
Eagles' Jalen Hurts: Overcomes two picks against Titans
Hurts completed 26 of 37 passes for 264 yards and two touchdowns with two interceptions in Sunday's 24-20 win over Tennessee. He added 16 yards on five carries.
Both picks led to points for the Titans, including a fourth-quarter field goal that put the home side up 20-17 with less than two minutes left. Hurts atoned for his mistakes, however, leading a nine-play, 65-yard drive that was capped by a three-yard TD strike to Darius Cooper that won the game. Hurts has already thrown five touchdowns in two games after tossing a career-high 25 in 16 regular-season contests in 2025, and he'll look to keep that momentum going in a Week 3 road trip to Chicago.
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Mansoor Delane CB | KC
Chiefs' Mansoor Delane: Cleared to play Week 2
Delane (shoulder) is active for Sunday's game against the Colts.
Delane suffered a shoulder injury during the Chiefs' Week 1 win over the Broncos, but he did enough during the week and Sunday's pregame warmups to be cleared to play against Indianapolis. If Delane suffers a setback against Indianapolis, then Kristian Fulton would likely enter the game at outside corner.
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Chris Jones DE | KC
Chiefs' Chris Jones: Good to go for Week 2
Jones (calf) is active for Sunday's game against the Colts.
Jones has been given the green light to play Sunday after working through a calf injury throughout the week. Even though he'll suit up, the veteran defensive lineman may operate on a limited snap count, which would result in Peter Woods, Bryson Eason and Khyiris Tonga all operating in elevated roles.
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Garrett Nussmeier QB | KC
Chiefs' Garrett Nussmeier: Emergency QB3 vs. Indianapolis
Nussmeier (coach's decision) is inactive but will serve as the Chiefs' emergency third quarterback against the Colts on Sunday.
For a second consecutive week, Nussmeier will be the emergency QB3. That means the rookie seventh-rounder is prohibited from playing Sunday night unless both Patrick Mahomes and Justin Fields leave the game due to injury, illness or ejection.