NFL Player News

Mariota sustained an undisclosed injury in the first quarter of Sunday's game against the Colts in London and headed to the locker room for further evaluation, Nicki Jhabvala of The Athletic reports.

Making a second straight start in place of Jayden Daniels (elbow), Mariota completed three of four pass attempts for 46 yards and ran once for a 35-yard gain before he appeared to get hurt on a third-down sack with 7:05 remaining in the quarter. Athan Kaliakmanis came on to replace Mariota under center on the Commanders' next possession.

The Rams are "optimistic" that Donald (back), who has been ruled Sunday's game against the Eagles, will be available to play in Week 5 versus the Bills, Mike Garafolo of NFL Network reports.

Donald will miss his second game of the season but his first due to injury, after he was absent for the Week 1 loss to the 49ers in Australia while he worked to regain full conditioning after a two-plus-year layoff from game action. The 35-year-old played more than half of the defensive snaps in Weeks 2 and 3, so his absence for Sunday's contest will leave a major void along the line. Braden Fiske and Kobie Turner could both be in line for heightened snaps to compensate for Donald's absence, while Tyler Davis may also see his role grow as the Rams' first lineman up off the bench.

Smith (hamstring), who has been ruled out for Sunday's game against the Rams, is viewed "at very best, questionable" for the Eagles' Week 5 game versus the Jaguars in London, Mike Garafolo of NFL Network reports.

After he was unable to practice in any fashion during Week 4 while tending to the hamstring injury, Smith looks like he could be in store for a multi-game absence. The Eagles will likely wait and see how Smith fares in practice during the upcoming week before deciding whether he'll make the trip to London. While they are without Smith's services for at least the matchup with the Rams, the Eagles will look to get by with Dontayvion Wicks, Makai Lemon, Darius Cooper and Elijah Moore as their main options at receiver.

The Steelers could be without Dean for "a couple of weeks" after he exited Thursday's 27-24 loss to the Browns due to an ankle injury, Ian Rapoport of NFL Network reports.

Pittsburgh's depth at cornerback was already being tested after Joey Porter sat out the team's first three games before he was traded to the Cowboys on Wednesday, so the loss of Dean for any length of time would represent another big hit to the secondary. Assuming the ankle injury keeps Dean out for at least the Steelers' Week 5 game against the Colts, Asante Samuel and Daylen Everette would likely be called upon to serve as starters at the boundary corner spots.

Harmon is expected to miss multiple weeks after exiting Thursday's 27-24 loss to the Browns due to a foot injury, Ian Rapoport of NFL Network reports.

While the Steelers are confident that Harmon avoided a long-term or season-ending injury, the foot issue could be significant enough to force him to injured reserve, which would require him to miss at least four games. A 2025 first-round pick, Harmon had gotten off to a solid start to his second NFL season, racking up 12 tackles, 1.5 sacks and a forced fumble through Pittsburgh's first four contests.

Dalton is expected to serve as the Eagles' No. 3 quarterback for Sunday's game against the Rams, while Tanner McKee moves up to second on the depth chart as the top backup to Jalen Hurts, Mike Garafolo of NFL Network reports.

Dalton had been active ahead of McKee as the No. 2 quarterback for each of the Eagles' first three games of the season, but he didn't see any action until midway through the second quarter of Monday's 27-7 loss to the Bears, when Hurts exited to get checked for a concussion. After three consecutive handoffs to Saquon Barkley got the Eagles to two-yard line to set up a third-and-goal, Dalton proceeded to throw a back-breaking interception in the end zone on his lone pass attempt before Hurts returned for the ensuing possession. The costly pick looks to have been enough to cost Dalton the No. 2 job, at least for one week.

McKee is expected to be active for Sunday's game against the Rams as the top backup to starter Jalen Hurts, while Andy Dalton serves as the Eagles' No. 3 quarterback, Mike Garafolo of NFL Network reports.

Despite operating as Hurts' primary backup in 2025, McKee slid to third on the depth chart entering the 2026 season after the Eagles acquired Dalton in a trade with the Panthers back in March. Dalton didn't see any snaps on the season until midway through the second quarter of Monday's 27-7 loss to the Bears, when Hurts made a brief exit from the contest to get checked for a concussion. After three consecutive Saquon Barkley carries got the Eagles near the goal line, Dalton proceeded to throw a costly interception in the end zone on his lone pass attempt before Hurts returned for the next possession. The gaffe appears to have resulted in Dalton turning the backup gig over to McKee, at least for one week.

Mayfield's dislocated right thumb could keep him out anywhere from 3-to-6 weeks, depending on how quickly he's able to resume gripping the football without issue, Adam Schefter of ESPN reports.

Head coach Todd Bowles previously acknowledged that Mayfield would miss at least three weeks due to the injury, which he sustained in last Sunday's loss to the Vikings. Though Mayfield was cleared of any tendon or ligament damage and won't need surgery on the thumb on his throwing hand, the two-time Pro Bowler required stitches to close a wound caused by the dislocation. Despite facing a loose recovery timeline that could keep him out for more than four games, Mayfield avoided placement on injured reserve Saturday, which signals that the Buccaneers are still holding out hope that he might be ready to go after a three-week absence. For however long Mayfield ends up being sidelined, the Buccaeneers will turn to undrafted rookie Jalon Daniels to direct the offense, beginning with Sunday's game versus Green Bay.

McCaffrey (coach's decision) is inactive for Sunday's game against the Colts in London.

McCaffrey suited up for the first time all season in the Commanders' Week 3 win over the Seahawks, but his playing time was contained to special teams. Even with top wideout Terry McLaurin (hamstring) sitting out Sunday, McCaffrey won't be called upon to provide depth at receiver. Washington will go with Stefon Diggs, Antonio Williams, Treylon Burks, Dyami Brown and Jaylin Lane as its available options at the position.

Leonard is inactive for Sunday's game against the Commanders in London as the Colts' emergency No. 3 quarterback.

Leonard hasn't been active for any of the Colts' first four games after Anthony Richardson beat him out for the No. 2 job coming out of the preseason. The second-year player out of Notre Dame will only be available in the event both starter Daniel Jones and Richardson are unable to finish the game.