Estime rushed 14 times for 94 yards and a touchdown while bringing in his only target for four yards in the Saints' 34-26 win over the Titans on Sunday.

After both Estime and fellow back Evan Hull ceded plenty of work to jack-of-all-trades veteran Taysom Hill in a Week 16 win over the Jets, head coach Kellen Moore opted for a more traditional ground attack Sunday. Estime was the primary beneficiary, outpacing Hill and Hull by three and two carries, respectively, and recording a career-best rushing yardage total in the process. The 2024 fifth-round pick of the Broncos ripped off a 32-yard touchdown run to seal the win with just under four minutes remaining, and given his production, Estime looks like a strong candidate to helm the running game again in a Week 18 road matchup against the Falcons, assuming Alvin Kamara (knee) remains out.

Henderson (concussion) rushed 19 times for 82 yards and wasn't targeted in Sunday's 42-10 win over the Jets.

Henderson had a 19-8 edge in carries over Rhamondre Stevenson, but Stevenson had all five of the targets between the two and scored both of the touchdowns among New England's running backs. Henderson cleared concussion protocol prior to Sunday's win and avoided any setbacks, so the rookie second-round pick will continue to operate as the 1A option in New England's productive running back platoon in Week 18 against the Dolphins. The Patriots would secure the top seed in the AFC with a win over Miami and a Broncos loss to the Chargers.

Walker carried the ball 15 times for 51 yards and caught both his targets for six yards in Sunday's 27-10 win over the Panthers.

It was Zach Charbonnet's turn to post big numbers out of the Seattle backfield, as he delivered 110 rushing yards and two TDs while Walker played second fiddle. Walker will still head into a Week 18 clash with the 49ers needing only 70 rushing yards to reach 1,000 for the second time in his career, and with the Seahawks in line to secure the No. 1 seed in the NFC with a win, he should get every opportunity to hit that milestone.

Etienne rushed 17 times for 76 yards and caught two of three targets for 16 yards in Sunday's 23-17 win over the Colts.

Both of Jacksonville's touchdowns came on Trevor Lawrence touchdown runs, as Etienne was held out of the end zone after scoring five rushing touchdowns and five receiving touchdowns over the previous seven games. Etienne has handled at least 15 touches in all but two games this season, and he's likely to see another hefty workload in Week 18 against the Titans. Jacksonville would clinch the AFC South crown with a win over Tennessee or a Texans loss to the Colts.

Taylor rushed the ball 21 times for 70 yards and a touchdown in Sunday's 23-17 loss to the Jaguars. He added three receptions on six targets for 14 yards.

The Jaguars boast one of the best run defenses in the league, and they made running room hard to come by for Taylor. His longest rush went for only 10 yards, though he still turned in a solid fantasy performance thanks to his volume of touches as well as a three-yard touchdown plunge early in the second quarter. Taylor now has 20 total touchdowns for the season and has at least 70 yards from scrimmage in five consecutive contests. It's unclear if the Colts will alter their backfield usage in Week 18 after being eliminated from playoff contention, but Taylor will face a very tough Texans run defense to close the 2025 campaign.

Irving rushed nine times for 19 yards and brought in five of six targets for 14 yards in the Buccaneers' 20-17 loss to the Dolphins on Sunday.

Irving was surprisingly stonewalled on the ground by a typically vulnerable Dolphins defense, and although he made solid contributions from a PPR perspective with his five catches, they went for minimal yardage. Irving had rushed for at least 55 yards in each of his first four games back from a long absence due to shoulder and foot injuries, so Sunday's downturn was particularly drastic and ill-timed for fantasy managers rolling with him in their playoff contests. Irving will look to atone in a critical Week 18 home matchup against the Panthers that presents a chance for the Bucs to still win the division, with a Week 18 win coupled with a Falcons loss in one of the next two games.

Brown carried the ball 22 times for 101 yards and two touchdowns and caught all three of his targets for 40 yards in Sunday's 37-14 win over the Cardinals.

The third-year back put the game on ice with a pair of third-quarter scores, from six yards and one yard out. Brown has scored multiple TDs in three of the last four games while topping 100 scrimmage yards in five of the last seven, and he needs just 53 more rushing yards to reach 1,000 on the season for the first time. He'll look to reach that milestone in Week 18 against the Browns.

Pollard rushed 18 times for 85 yards and brought in both targets for 10 yards in the Titans' 34-26 loss to the Saints on Sunday.

Despite the game going down as yet another in the loss column for the Titans, Pollard continued his productive stretch run with his fourth consecutive outing with greater than 80 rushing yards. Pollard had actually cleared the century mark in the three prior games in that sample, so even though Sunday's production qualified as a downturn, it was enough to vault the veteran back over the 1,000-yard mark for the fourth consecutive campaign. Pollard will need a very reachable 46 rushing yards in the Week 18 road matchup against the Jaguars to eclipse his current career high of 1,079 yards, which he established in his debut season in Tennessee in 2024.

Carter carried the ball seven times for 29 yards and caught two of four targets for 14 yards in Sunday's 37-14 loss to the Bengals.

The Cardinals were down 23-7 at halftime and didn't get closer, so game script wasn't in Carter's favor as a runner. He still caught multiple passes for the sixth time in seven games however, a stretch in which he's put together 214 yards on the ground with a 4.6 YPC while adding a 21-169-0 line on 30 targets. Arizona has nothing on the line but draft positioning in Week 18, but the Cardinals also don't have many other healthy RBs, so Carter could remain the starter in the team's season finale against the Rams.

Stevenson rushed eight times for 47 yards and a touchdown while catching all five of his targets for 55 yards and a touchdown in Sunday's 42-10 win over the Jets.

Stevenson scored on consecutive drives, running in a one-yard touchdown in the first quarter and catching a 22-yard touchdown pass on the first play of the second as the Patriots raced out to a 21-0 lead. He had eight carries compared to 19 for TreVeyon Henderson, who cleared the NFL's five-step concussion protocol prior to Sunday's win, but Henderson wasn't targeted in the passing game. Stevenson has churned out at least 77 scrimmage yards in four consecutive games, remaining productive despite ceding most of the rushing opportunities to Henderson in recent weeks. Both running backs will likely continue to play substantial roles in Week 18 against the Dolphins, as New England can earn the top seed in the AFC and a wild-card round bye with a win over Miami and a Denver loss to the Chargers.