Dowdle rushed 19 times for 45 yards and caught five of seven targets for 55 yards in Sunday's 30-27 overtime win over the Falcons.

Although he didn't find the end zone and averaged just 2.3 yards per carry, Dowdle still notched his fourth 100-yard performance of the season in the Week 11 win. The Panthers' didn't lean on the rushing attack as heavily as usual, as quarterback Bryce Young had a career day with 448 passing yards and three touchdowns. Dowdle has now received 20 or more touches in five of Carolina's last seven games, reinforcing his role as a workhorse back. He'll look to improve his efficiency in a favorable Week 12 matchup against a 49ers defense that's struggled as of late.

Brown rushed 18 times for 99 yards and caught six of eight targets for 28 yards in Sunday's 34-12 loss to the Steelers.

Brown has rushed for at least 73 yards in three of his last four games after failing to exceed 47 rushing yards in a game through Week 6. He handled a workhorse role in the absence of top backup Samaje Perine (ankle), as Brown set season highs with 24 touches and 127 scrimmage yards. After a slow start, Brown has started to deliver the gaudy production fantasy managers expected on the heels of his breakout 2024 campaign. New England's stout run defense will be tasked with trying to slow down Brown in Week 12.

Swift rushed 21 times for 90 yards and didn't catch his only target in Sunday's 19-17 win over the Vikings.

For the second consecutive week since returning from a groin injury, Swift worked as the top option in Chicago's backfield but was kept out of the end zone while backup Kyle Monangai scored a rushing touchdown. Swift has rushed for at least 80 yards in four of his last five appearances heading into a Week 12 home game against the Steelers, so he remains a reliable source of yardage despite Monangai's involvement by the goal line.

Tuten was forced out of Sunday's game against the Chargers with an ankle injury.

Before his departure from the contest, Tuten carried 15 times for 74 yards and a TD, while working in tandem with Travis Etienne. While he's sidelined, LeQuint Allen is available to handle added RB snaps versus Los Angeles.

Mitchell is active for Sunday's game against the Broncos, Matt McMullen of the Chiefs' official site reports.

With Isiah Pacheco (knee) inactive, Brashard Smith and Mitchell are on hand to work behind Kareem Hunt on Sunday. Mitchell is thus slated to make his season debut with the Chiefs, while Clyde Edwards-Helaire was not elevated from the team's practice squad ahead of Week 11 action.

Hunter (coach's decision) is inactive for Sunday's game against the Seahawks, Stu Jackson of the Rams' official site reports.

Hunter will be sidelined for a fourth consecutive game as the Rams go with three active running backs in Kyren Williams, Blake Corum and Ronnie Rivers. Hunter's next opportunity to play is Week 12 against the Buccaneers on Sunday, Nov. 23.

Jacobs (knee) won't return to Sunday's game at the Giants.

Jacobs visited the blue medical tent in the first quarter, attempted to play through whatever was bothering him and then was deemed questionable to return due to a knee injury. During the Packers' first possession of the second half, he was ruled out, leaving Emanuel Wilson to lead the backfield and Chris Brooks also available at the position.

James (coach's decision) is inactive for Sunday's game against the Cardinals, Briana Jeannel of the 49ers' official site reports.

The running back continues to be a healthy scratch for the 10th consecutive week. Christian McCaffrey, Brian Robinson and Isaac Guerendo remain ahead of James on the depth chart.

Knight (ankle) is active for Sunday's game against the 49ers, Darren Urban of the Cardinals' official site reports.

Knight exited in the fourth quarter of last Sunday's loss at Seattle due to an ankle injury that left him limited on all three of the Cardinals' Week 11 practice reports. Adam Schefter of ESPN then reported Saturday evening that Knight was in line to play this weekend, which now will come to pass. Knight and Emari Demercado have split most of the touches afforded to the team's running backs over the last two games, with each earning 22 apiece. However, Demercado has been far more effective than Knight, out-producing him 182 to 80 in terms of yards from scrimmage during that span.

Vidal (thigh) returned to Sunday's game against the Jaguars, Kris Rhim of ESPN.com reports.

Vidal had exited the contest due to a thigh issue, but he was able to return to the Chargers' Week 11 backfield, which also includes Amar Johnson and Trayveon Williams.