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Ryan Mathews RB | PHI
Eagles' Ryan Mathews: Downgraded to out
Mathews (knee) will not return to Sunday's game against Seattle, Jeff McLane of the Philadelphia Enquirer reports.
Mathews left in the first half of Sunday's game and was initially considered questionable to return. With Darren Sproles (ribs) also ruled out, Kenjon Barner and Wendall Smallwood will handle all the running back duties for the rest of the game.
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Jerick McKinnon RB | KC
Vikings' Jerick McKinnon: Held to 41 total yards
McKinnon rushed for 44 yards on 16 carries and lost three yards on a single catch in Sunday's win over Arizona.
As the weeks go on, McKinnon's 95-total-yard performance against the Giants in Week 4 looks further and further away. That game aside, McKinnon has been held under four yards per carry in every other contest in which he has carried the ball at least six times. With Minnesota's offensive line in shambles and Matt Asiata among the game's biggest goal-line vultures, McKinnon's prospects do not look good moving forward.
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Dwayne Washington RB | DEN
Lions' Dwayne Washington: Leads Lions in carries
Washington rushed 13 times for six yards and caught both of his targets for 15 yards Sunday against the Jaguars.
Washington received 13 carries Sunday compared to four for starter Theo Riddick, but couldn't do anything against the fourth-most generous run defense in the NFL. Washington was much less involved in the passing game, though, whereas Riddick was a pivotal factor, seeing 10 looks compared to Washington's two. While it isn't crystal clear how the distribution of touches will end up in any given week, an offensive game plan emphasizing Washington on the ground and Riddick through the air figures to be a sustainable approach moving forward.
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Ezekiel Elliott RB | LAC
Cowboys' Ezekiel Elliott: Grinds out results in win over Ravens
Elliott gained 97 yards on 25 carries and added four receptions on five targets for an additional 30 yards in Sunday's 27-17 win over the Ravens.
Elliott got off to a slow start against the Ravens' top-ranked run defense, but he continued to chip away and has now generated at least 127 scrimmage yards in eight of the last nine games. He continues to grind out impressive results regardless of the opponent, and consequently, he's become one of the front-runners for the MVP award. With a choice matchup against the Redskins awaiting on Thanksgiving Day, top-level production is seemingly in store once again for Elliott.
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Ryan Mathews RB | PHI
Eagles' Ryan Mathews: Questionable to return
Mathews is questionable to return to Sunday's game against the Seahawks after suffering a knee injury.
Mathews left with his knee injury in the first half Sunday and the team has yet to release any specifics on the issue. Darren Sproles and Kenjon Barner will see some extra snaps while Mathews is out.
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Mike Gillislee RB | NE
Bills' Mike Gillislee: Takes over for injured LeSean McCoy
Gillislee rushed 14 times for 72 yards after replacing an injured LeSean McCoy (thumb) against the Bengals on Sunday.
The Bills relied heavily on the run in a defensive-minded 16-12 victory, even after their starting running back went down. Gillislee served as the workhorse in McCoy's absence, and makes for a strong upside play if McCoy can't return next week against the Bengals. He has averaged 5.8 yards per carry thus far, and still has four touchdowns in the past six games despite not having scored Sunday.
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Doug Martin RB | LV
Buccaneers' Doug Martin: Totals 105 yards of offense in Week 11 win
Martin gained 63 yards on 24 carries and secured three of four targets for 42 yards in Sunday's 19-17 victory over the Chiefs. He also recovered a fumble.
Martin toughed things out on the ground against a stingy Chiefs front, while also contributing a season-high 42 receiving yards and season-long 27-yard reception. The veteran running back looked quick and decisive, despite often finding running room to be at a premium, and his 63 yards rushing actually represented a high-water mark in that category in his injury-shortened campaign. While he looks to be back at full health and clearly capable of taking on a starter's workload, Martin will have a tough assignment in Week 12 against the Seahawks.
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Ameer Abdullah RB | JAC
Lions' Ameer Abdullah: Will be evaluated Tuesday
Abdullah is scheduled for an evaluation of his left foot Tuesday to determine if he can begin to practice, Ian Rapoport of NFL Network reports.
Sidelined since suffering a foot injury in Week 2, Abdullah is one of the Lions' candidates to be activated from injured reserve before season's end. In fact, Rapoport noted that Abdullah could return in three weeks, which would provide the Lions' backfield with another dual threat alongside Theo Riddick. No matter when he's cleared to return, Abdullah seems like a good bet to make his presence felt in the near future.
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Lorenzo Taliaferro RB | BAL
Ravens' Lorenzo Taliaferro: Inactive for Sunday's game
Taliaferro (thigh) is inactive for Sunday's game against the Cowboys.
After sitting out practices Thursday and Friday with the thigh injury, Taliaferro was never considered to have a great shot at suiting up in Week 11. The third-year running back is buried on the depth chart behind Terrance West, Kenneth Dixon and Javorius Allen and may have been a healthy inactive even if he had been available to play.
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Thomas Rawls RB | JAC
Seahawks' Thomas Rawls: Expected to split touches Sunday
Rawls is expected to get plenty of snaps Sunday against the Eagles, but C.J. Prosise is being treated like the starter, according to NFL Network's Ian Rapoport.
The availability of both backs, and the possibility that both will get plenty of touches, is obviously not an ideal situation for fantasy owners, as each player will limit the upside of the other. Nevertheless, Rawls had the job before his injury, and a solid performance Sunday could boost his touches for the following week.