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Mike Gillislee RB | NE
Patriots' Mike Gillislee: Logs 12 carries Sunday
Gillislee carried 12 times for 49 yards in Sunday's 33-30 loss to the Panthers.
After scoring three TDs in Week 1 and one in Week 2, Gillislee has logged back-to-back 12-carry efforts without finding the end zone. He's not much of a factor in the Patriots' passing game, so he'll head into Week 5's contest against the Buccaneers on Thursday as a TD-dependent fantasy option.
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Dalvin Cook RB | DAL
Vikings' Dalvin Cook: Sustains left knee injury
Cook has been ruled out of Sunday's game against the Lions due to a knee injury.
On the first play of the Vikings' second possession after halftime, Cook galloped for 10 yards before going down with a non-contact injury to his left knee, per Courtney Cronin of ESPN.com. Cook immediately grabbed at his knee but was able to walk to the locker room under his own power. While the Vikings will surely touch on Cook's health in the aftermath of the game, Jerick McKinnon and Latavius Murray will head the backfield Sunday and perhaps beyond.
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Melvin Gordon RB | BAL
Chargers' Melvin Gordon: In uniform Sunday
Gordon (knee) is listed as active for Sunday's game against the Eagles.
Gordon, who the Chargers listed as a full practice participant Friday, will suit up Sunday, as expected. In the process, he'll take aim at an Eagles defense that has held opponents to an average of 75 rushing yards per game to date.
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Alvin Kamara RB | NO
Saints' Alvin Kamara: Force in passing game Sunday
Kamara rushed five times for 25 yards and brought in all 10 of his targets for 71 yards and a touchdown in Sunday's 20-0 win over the Dolphins in London. He also totaled 23 yards on his sole kickoff return.
After a trio of serviceable performances to start his career, Kamara's Week 4 tally could be considered a breakout effort, considering his reception total paced the Saints. The 22-year-old rookie was a trusted outlet option for QB Drew Brees throughout the afternoon and then capped off the scoring on the day with a 12-yard touchdown reception late in the fourth quarter. Kamara's usage in the passing game is naturally an encouraging development for fantasy owners, one that he'll look to uphold when the Saints take on the Lions in Week 6 following a Week 5 bye.
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Cameron Artis-Payne RB | CAR
Panthers' Cameron Artis-Payne: Available in Week 4
Artis-Payne is listed as active Sunday in New England, Joe Person of The Charlotte Observer reports.
Artis-Payne will be available on game day for the first time this season. With all four running backs on the 53-man roster active, though, it remains to be seen exactly how he'll be utilized. More than likely, Artis-Payne is slated for special-teams duty.
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Melvin Gordon RB | BAL
Chargers' Melvin Gordon: Expected to play Sunday
Gordon (knee) will play Sunday against the Eagles, a source told Adam Schefter of ESPN.
Gordon was able to practice fully Friday and head coach Anthony Lynn said he expected him to play. Still, this report would seem to remove any questions if he'll be ready for Sunday's game.
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Rob Kelley RB | NO
Redskins' Rob Kelley: Listed as questionable
The Redskins have officially listed Kelley (ribs) as questionable for Monday night's game against the Chiefs, John Keim of ESPN reports.
Kelley, who has been limited at practice since a suffering a rib cartilage injury Week 2 against the Rams, appears on track to be a true game-time decision Monday night. Should the 24-year-old ultimately be ruled out for a second straight week, Samaje Perine would presumably remain the team's primary early-down runner in his place, while Chris Thompson would continue getting reps in passing situations.
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D'Onta Foreman RB | CLE
Texans' D'Onta Foreman: Trusted for all three downs
Head coach Bill O'Brien said Friday that Foreman can handle all three downs, Leslie M. Koerdt of the Houston Chronicle reports. "We use him in the passing game," O'Brien stated. "He's not just a runner. ... I see him as a three-down back."
At this point, the presence of Lamar Miller at the top of the depth chart seems to be the only thing between Foreman and a significant workload. Still, Foreman has earned 17 offensive snaps in back-to-back games, during which he's totaled 20 carries for 65 yards and two catches (on three targets) for 65 yards. With such usage, he's certainly a player to stash in the event he gains a larger role.
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Matt Breida RB | SF
49ers' Matt Breida: Could take on expanded role
Breida would be in line for an expanded role if Carlos Hyde (hip) were to be absent or limited Sunday against the Cardinals, Daniel Brown of The San Jose Mercury News reports.
While Hyde hasn't left much behind this season, Breida has picked up most of the scraps with 11 carries and six targets. No. 3 back Raheem Mostert is mostly a special-teams contributor who only has four offensive touches all season. It all adds up to potential for Breida to handle a heavy Week 4 workload if the Niners' top rusher is absent, though Hyde does seem more likely than not to play.
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Dwayne Washington RB | DEN
Lions' Dwayne Washington: Ruled out again
Washington (quad) has been ruled out for Sunday's game in Minnesota.
Washington will miss a second straight game, allowing Zach Zenner to step in as the No. 3 back. Zenner managed just five yards on three carries in Sunday's 30-26 loss to the Falcons.