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Matt Breida RB | SF
Bills' Matt Breida: Set for No. 2 role
Breida's teammate Zack Moss will be a healthy inactive for the third time in four weeks Sunday.
Devin Singletary should lead the backfield in carries, not to mention the team has a running quarterback in Josh Allen, but expect Breida to be sprinkled into the offense both as an occasional runner and pass catcher. Perhaps a longshot touchdown in a game the Bills are heavily favored in would provide some assistance to those deeply desperate for running back points.
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Devin Singletary RB | NYG
Bills' Devin Singletary: Set to lead backfield again
Singletary's teammate Zack Moss will be a healthy inactive for the third time in four weeks Sunday.
Singletary saw 83 percent of the offensive snaps and totaled 89 yards from scrimmage in the overtime loss to Tampa Bay last week with Moss out, even though he only had four rushing attempts. Expect Singletary to lead the Buffalo backfield once again, though the game script in Buffalo is all over the board from week to week. He could see more carries than usual -- certainly more than four -- with Moss out again and with running quarterback Josh Allen hobbled by a foot injury.
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Zack Moss RB | CIN
Bills' Zack Moss: Another healthy scratch
Moss will be a healthy scratch Week 15 against Carolina.
Moss will be sidelined for his second contest in a row, as well as his third in the past four games. Look for the backfield to once again be led by Devin Singletary, with Matt Breida also available for what is likely a passing-down role.
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Tony Pollard RB | TEN
Cowboys' Tony Pollard: Suiting up, may be limited Week 15
Pollard (foot) is active for Sunday's game against the Giants, Michael Gehlken of The Dallas Morning News reports.
Though Pollard will make his return to action following a one-game absence due to a torn plantar fascia of his left foot, the third-year back is expected to play "a couple dozen snaps" as the Cowboys look to ease him back into action, per Tom Pelissero of NFL Network. With that in mind, starter Ezekiel Elliott projects to start and lead the position group in both snaps and touches, and third-stringer Corey Clement is expected to have a small role in the game plan behind Elliott and Pollard. The likelihood of Dallas limiting Pollard's workload makes him a less appealing option in fantasy lineups than usual coming off the injury.
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James Conner RB | ARI
Cardinals' James Conner: Suiting up Sunday
Conner (ankle) is listed as active Sunday at Detroit.
Conner's usage has ballooned since Chase Edmonds sustained a high ankle sprain Week 9. In four contests in the meantime, Conner earned between 81 and 96 percent of offensive snaps per game on his way to 83 touches for 399 yards from scrimmage and five total TDs. Unfortunately for Conner, he picked up his own ankle injury near the end of the Cardinals' Week 14 loss to the Rams, capping him to one limited practice this week. Despite being listed as questionable, he'll be available Sunday as the Cards welcome back Edmonds, whom the team activated from IR on Saturday, to the lineup. Such a development could result in decreased usage for Conner, who averaged 13.9 touches per game to Edmonds' 11.8 in outings in which both were active this season.
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Nyheim Miller-Hines RB | NO
Colts' Nyheim Hines: Sneaks into end zone Saturday
Hines caught one of two targets for a six-yard touchdown in Saturday's 27-17 win over the Patriots.
He opened the scoring late in the first quarter on a trick play by the Colts, as Jonathan Taylor took a direct snap and handed it to Carson Wentz, who then shoveled it to Hines to take into the end zone behind a convoy of blockers that included Taylor. Unfortunately for Hines, it was his only touch of the night as Indy built a 17-0 lead by halftime and then leaned on Taylor to kill the clock. The TD was Hines' third of the season but his first receiving score. Given his diminished role in the offense, he'll remain a touchdown-dependent fantasy option in Week 16 against the Cardinals.
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Jonathan Taylor RB | IND
Colts' Jonathan Taylor: Extends TD streak to 11 games
Taylor carried the ball 29 times for 170 yards and a touchdown in Saturday's 27-17 win over the Patriots.
The Colts held a 17-0 lead at halftime thanks to a special-teams TD and a bit of trickery to Nyheim Hines, but Taylor was still able to grind his way to another 100-yard performance while the team killed the clock in the second half -- until he erupted for a 67-yard touchdown run with two minutes left in the game, squashing any hope New England might have had of a comeback. Taylor has 19 TDs on the season, leaving him one short of the Colts' franchise record of 20 set by Lenny Moore in 1964, and his 11 consecutive games with a rushing TD ties the single-season NFL record held by LaDainian Tomlinson and John Riggins, although Tomlinson's overall record of 14 straight games across two seasons remains a little further down the road. Taylor will look to keep tracking down history in Week 16 against the Cardinals.
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Brandon Bolden RB | LV
Patriots' Brandon Bolden: Effective as receiver Saturday
Bolden carried the ball four times for three yards and caught three of five targets for 41 yards in Saturday's 27-17 loss to the Colts.
With Damien Harris (hamstring) sidelined for the contest, Rhamondre Stevenson was the primary ball carrier for the Patriots, while Bolden did most of his damage as a pass catcher. The veteran back actually wound up leading the New England backfield in scrimmage yards, 44-40 over Stevenson. It's the first time Bolden has seen more than five touches in a game since Week 10, but his role will likely shrink again if Harris is back in the lineup for a Week 16 rematch with the Bills.
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Javonte Williams RB | DAL
Broncos' Javonte Williams: Expected to play against Bengals
Williams (knee), who is listed as questionable for Sunday's game against the Bengals, is expected to play, Adam Schefter of ESPN reports.
He was unable to practice Thursday but was a limited participant Wednesday and Friday. Head coach Vic Fangio told reporters Friday that Williams isn't expected to have any limitations against the Bengals on Sunday. Melvin Gordon (thumb/hip) is also expected to be available Week 15, so the two running backs should operate in their usual timeshare out of the backfield.
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Melvin Gordon RB | BAL
Broncos' Melvin Gordon: On track to play Sunday
Gordon (thumb/hip), who is listed as questionable for Sunday's game against the Bengals, is expected to play, Adam Schefter of ESPN reports.
Gordon was a limited participant in practice all week before receiving the questionable designation. Javonte Williams (knee) is also listed as questionable but expected to be active, so the two running backs should continue to work in their usual timeshare versus Cincinnati. Their statuses will be confirmed when Denver posts its inactive list 90 minutes prior to Sunday's 4:05 p.m. ET kickoff.