Houser (0-1) allowed three runs (one earned) on seven hits and a walk while striking out four over 5.1 innings to take the loss Wednesday versus the Padres.

The Giants' defense didn't do Houser any favors, with errors in the first and fifth innings leadings to the first two runs on his line. This was the right-hander's Giants debut, and he threw 58 of 86 pitches for strikes in a decent performance. He signed with San Francisco for two years and $22 million after splitting last season between the Rays and the White Sox, posting a 3.31 ERA, 1.28 WHIP and 92:38 K:BB across 125 innings over 21 starts in a bounce-back season. He has a favorable home park, but the Giants' offense hasn't been all that encouraging with just 13 runs scored over six games this season. Houser is tentatively lined up to make his next start at home versus the Phillies next week, which could set him up for a two-start week.

Butto was removed during the eighth inning of the Giants' 7-1 loss to the Padres on Wednesday due to right arm tightness, Justice delos Santos of The San Jose Mercury News reports.

Butto was brought in for the eighth to keep the Giants' deficit at two runs, but he recorded just one out while allowing four runs on three hits and four walks, tossing 28 pitches (eight strikes) before being pulled. The Giants should have an update over the next couple of days once Butto undergoes some tests on his arm.

Laureano went 2-for-4 with a two-run home run and a second run scored in Wednesday's 7-1 win over the Giants.

Laureano gave the Padres some breathing room with his eighth-inning blast. This was his second multi-hit effort in five contests this season, and he's added two home runs, four RBI, three runs scored and a stolen base while batting .389 so far. Laureano was given a full day off Tuesday and started at designated hitter for the first time this season Wednesday. While he may not play the field all the time, he should be in the lineup most days, especially if he continues to hit well.

Gallen (1-1) notched the win Wednesday against the Tigers, allowing no runs on four hits and no walks in six innings. He struck out two.

Two of the hits allowed went for extra bases, but Gallen was still able to keep Detroit out of the scoring column Wednesday. Although right-hander wasn't dominant, he tossed 58 of his 88 pitches for strikes and bounced back in a big way after allowing four runs in four innings during his season debut. Gallen is set for a tough matchup on paper versus the Mets in his next scheduled start, though New York has stumbled out of the gates with .648 OPS as a team through six games.

Pivetta (1-1) allowed one hit and two walks while striking out eight over five scoreless innings to earn the win over the Giants on Wednesday.

Pivetta's first start of the season was rough with six runs allowed, but he bounced back Wednesday in his second outing. In the 2025 regular season, he had eight outings with at least eight strikeouts, and he won six of those games with no-decisions in the other two. The right-hander now has a 6.75 ERA and a 12:5 K:BB across eight innings over his two starts this season. He is tentatively lined up to make his first road start of the year in Pittsburgh next week, which could be his first outing of a two-start week.

Skubal (0-1) took the loss Wednesday against the Diamondbacks, allowing one run on six hits and no walks in seven innings. He struck out three.

The All-Star left-hander certainly wasn't deserving of the loss, but the Tigers were shut out Wednesday. Skubal had the Arizona bats off balance throughout the outing, inducing 10 groundouts while pouring in 60 of his 87 pitches for strikes, but Corbin Carroll managed to take Skubal deep in the first innings for the game's lone run. Skubal has permitted a single run on the campaign to go with a pristine 9:0 K:BB through 13 innings so far, and he'll look to keep dealing his next time out versus the Twins in Minnesota.

Manager Dave Roberts told reporters Wednesday that Snell (shoulder) will "likely" face hitters once the Dodgers return to Los Angeles from their upcoming six-game road trip, David Vassegh of AM 570 LA Sports reports.

Snell was limited to bullpen sessions during spring training due to left shoulder fatigue, prompting his placement on the 15-day injured list to open the season. He continues to progress in his recovery, and it looks like he'll start to face live hitters once the Dodgers return from their upcoming road trip that will conclude next Wednesday. Roberts noted to reporters that Snell is on track to make his 2026 debut at the end of May.

Dodgers manager Dave Roberts told reporters Wednesday that Ohtani is scheduled to make his next start in the team's series finale against the Blue Jays on Wednesday, April 8, Jack Harris of the California Post reports.

The Dodgers plan on deploying a six-man rotation during the upcoming six-game road trip by mixing in a start for southpaw Justin Wrobleski, which means the next time Ohtani takes the mound will be during next week's World Series rematch. Ohtani dominated in his pitching debut against the Guardians on Tuesday, allowing one hit and three walks while striking out six across six scoreless innings to earn the win. Per Thomas Harrigan of MLB.com, Ohtani holds the longest regular-season scoreless streak among active pitchers at 22.2 innings, dating back to the 2025 campaign.

Palencia worked around a hit in a scoreless frame in Wednesday's 6-2 win over the Angels. He struck out one and walked none.

Palencia has now made two scoreless appearances so far this season but has yet to see any save opportunities. Those should come for the flamethrowing righty, who looked good as Chicago's closer last year and then continued to impress for Team Venezuela during its championship run through the World Baseball Classic last month. Palencia is the Cubs' unquestioned end-game option, with offseason additions Hunter Harvey and Phil Maton working ahead of him in setup roles.

Shaw went 2-for-4 with two RBI in Wednesday's 6-2 win over the Angels.

Shaw has started four of Chicago's first six games of the season in right field, with Michael Conforto also working into the mix. The former delivered his first multi-hit effort of the year Wednesday, and he should continue to see regular time in right until Seiya Suzuki (knee) is able to return. When Suzuki does come back, Shaw may shift into more of a super-utility role for the Cubs due to his ability to play the infield.