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Dylan Cease SP | TOR
Padres' Dylan Cease: Captures first win
Cease (1-0) earned the win Wednesday against Cleveland, surrendering one earned run on four hits and a walk while striking out seven batters across 6.1 innings.
Cease took a shutout into the seventh inning but was pulled after a Lane Thomas groundout plated a run for the Guardians. Cease's dominant showing, combined with a four-run third inning from the Padres' offense, allowed the 29-year-old righty to take home his first win of the new season fairly comfortably. He'll look to stay hot next week when he faces the Athletics on the road.
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Tarik Skubal SP | LAD
Tigers' Tarik Skubal: Gives up three runs in loss
Skubal (0-2) took the loss against the Mariners on Wednesday. He allowed three runs on six hits and three walks while striking out eight across 5.2 innings.
Skubal limited the damage to three runs despite allowing nine baserunners, but the Tigers were unable to generate enough offense to prevent his second straight loss to begin the year. The 28-year-old southpaw has failed to complete six innings in each of his first two starts and has begun the season with a 5.91 ERA and 1.50 WHIP across 10.2 innings. Things won't get easier for Skubal, as he's slated to face the Yankees next week at home.
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Zach Eflin SP | BAL
Orioles' Zach Eflin: Tough-luck loss in quality start
Eflin (1-1) was handed the loss after allowing three runs on eight hits and no walks in six innings Wednesday against Boston. He struck out five.
While Eflin registered a quality start, he was significantly outshined by Garrett Crochet's eight scoreless innings for the Red Sox. Trevor Story tagged Eflin for a solo home run in the second inning, and then the right-hander watched Ceddanne Rafaela and Rafael Devers plate one run apiece in the third frame. On tap for Eflin is a tough matchup early next week in Arizona, where he'll be seeking his third consecutive quality start to open the campaign.
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Garrett Crochet RP | BOS
Red Sox's Garrett Crochet: Dominant in eight scoreless innings
Crochet (1-0) earned the win after throwing eight scoreless innings on four hits and one walk Wednesday against Baltimore. He struck out eight.
After throwing five solid innings in his Red Sox debut Opening Day against Texas, Crochet built on that showing Wednesday by spinning eight shutout frames and scattering four singles for a brilliant performance on the road. The hard-throwing southpaw has allowed just two runs to go with 12 punchouts over 13 innings so far this year. Crochet will look to keep the good times rolling in his next start, which is slated to come at home against Toronto early next week.
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Connor Gillispie SP | PHI
Marlins' Connor Gillispie: Five strong innings against Mets
Gillispie didn't factor into the decision Wednesday against the Mets after allowing one run on four hits and no walks in five innings. He struck out six.
Facing a vaunted Mets lineup, Gillispie produced better results than when he gave up four runs in five frames during his first start of the year against Pittsburgh. Other than an RBI double from Pete Alonso in the first inning, it was rather smooth sailing for Gillispie. The 27-year-old right-hander threw just 73 pitches Wednesday, so he'll search for more length in his next scheduled start, which is scheduled to be a road rematch with the Mets early next week.
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Luis Castillo SP | CHW
Mariners' Luis Castillo: Earns first win of 2025
Castillo (1-1) came away with the win Wednesday against the Tigers. He allowed two runs on five hits and two walks while striking out five across seven innings.
Castillo limited the Tigers to three baserunners across the first four innings, but his shutout efforts were lost in the fifth frame when he gave up a solo homer to Trey Sweeney. Castillo gave up a second run in the same frame on a fielder's choice, but he managed to pitch into the seventh inning without much trouble and came away with the quality start and win. Castillo has started the season with a 3.00 ERA, 1.00 WHIP and 9:4 K:BB across 12 innings. He'll look for a second straight win in his next start, which is tentatively slated for next week against the Astros at home.
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Clay Holmes SP | CHC
Mets' Clay Holmes: Improves control in no-decision
Holmes didn't factor into the decision after allowing two runs (one earned) on six hits and two walks in 4.2 innings Wednesday against Miami. He struck out six.
After struggling with his control a bit Opening Day against Houston, Holmes did a better job of limiting the traffic Wednesday. Matt Mervis scratched a run across on a sacrifice fly in the third inning, and Otto Lopez reached on a fielder's choice later in the frame to bring in an unearned run following an error. Holmes is slated to face these same Marlins in a favorable matchup at home early next week, and he'll be looking to reach the 90-pitch threshold for the first time this season.
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Jeffrey Springs SP | ATH
Athletics' Jeffrey Springs: Gives up four earned runs in loss
Springs (1-1) took the loss against the Cubs on Wednesday. He gave up five runs (four earned) on five hits and four walks while striking out three across three innings.
Springs started out strong with two first-inning strikeouts, but things unravelled in the second frame when he gave up four runs, three of which came from a Seiya Suzuki home run. Springs needed 82 pitches to record just nine outs, which is a major step back from the six shutout frames he delivered in his season debut last week. The 32-year-old southpaw will look to get back in the win column in his next start, and he's lined up to face the Padres next week at home.
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Jameson Taillon SP | TOR
Cubs' Jameson Taillon: Fans seven in quality start
Taillon (1-1) got the win Wednesday against the Athletics. He allowed two runs on four hits and three walks while striking out seven across six innings.
It was a nice bounce-back performance for Taillon after he got knocked around for six runs in his first start against the Diamondbacks on Friday. His lone blemish came in the third inning when he gave up a two-run home run to Brent Rooker, but Taillon proceeded to retire 10 of the next 13 batters (including five strikeouts) and finished the game with 19 whiffs across 94 pitches. Taillon's next start is tentatively slated for next week at home against the Rangers.
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Sean Burke SP | CHW
White Sox's Sean Burke: Hit hard in Wednesday's loss
Burke (1-1) took the loss Wednesday as the White Sox were downed 6-1 by the Twins, surrendering six runs on seven hits over 4.1 innings. He struck out one without walking a batter.
After a sharp 2025 debut Opening Day, Burke crashed back down to earth in his second outing, although a rain delay of over three hours before the contest started likely played a big role in that. Four of the hits off the righty went for extra bases, including homers by Byron Buxton and Harrison Bader, and Burke got the hook after 77 pitches (50 strikes). He'll take a 5.23 ERA and 4:0 K:BB through 10.1 innings into his next start, which is scheduled to come on the road next week in Cleveland.