Altuve is absent from the lineup for Wednesday's contest in Toronto.

Altuve enters action Wednesday having gone just 2-for-29 at the plate over his last seven games, so he will get a day off to regroup. Ramon Urias will handle second base and Victor Caratini will be in the designated-hitter spot for the Astros.

Jackson (elbow) will start at third base and bat second in Wednesday's game against the Pirates.

Jackson was lifted for a pinch runner in the bottom of the eighth inning Tuesday after being hit in the right elbow by a 95.5-mph sinker, but he was fortunate to escape with little more than a bruise. The 25-year-old apparently isn't feeling too sore a day later, so he'll occupy his usual spot in the two-hole as the Orioles go up against Pirates ace Paul Skenes.

Gonzales is out of the lineup for Wednesday's game against the Orioles.

Gonzales will receive what appears to be a routine maintenance day after he started in each of the Bucs' last 12 games while slashing .250/.294/.333 with six runs and three RBI. Nick Yorke will fill in for Gonzales at second base and will bat sixth.

Antonacci is slashing .294/.442/.366 with zero home runs, 18 steals, a 13.5 percent walk rate and a 14.5 percent strikeout rate in 45 games for Double-A Birmingham.

Antonacci, who will play in the Arizona Fall League this year, was selected by the White Sox in the fifth round last year and received a $572,500 bonus out of Coastal Carolina. Despite the fact Antonacci has hit four home runs in 135 career games, he has been at least 50 percent better than the average hitter in every league he has played in, thanks to superb swing decisions and bat-to-ball ability. He has a 5.9 percent swinging-strike rate this year as an age-appropriate hitter at Double-A and his contact rates have always been elite. Antonacci has 45 steals in 112 games this year and figures to get a good amount of work at Triple-A next year, with a big-league debut not out of the question. Similar production to Nico Hoerner would be a best-case scenario for Antonacci in fantasy, although the latter's defense at the keystone is merely average while Hoerner's is double-plus, and the White Sox have a handful of infielders set to compete for playing time in the coming years.

Sosa is out of the lineup for Wednesday's game against the Mets.

Sosa will hit the bench Wednesday and give way to Bryson Stott at shortstop after he had started in the first two games of the series, going 2-for-7 with a double and a run. Despite his absence from the lineup, the 29-year-old Sosa still projects to draw the bulk of the starts at shortstop while Trea Turner (hamstring) is on the mend.

McNeil is absent from the lineup for Wednesday's game in Philadelphia.

McNeil had started each of the previous 10 contests for the Mets but will begin Wednesday's game on the bench. Luisangel Acuna will man second base and bat ninth.

Massey is out of the lineup for Wednesday's game against the Guardians.

The left-handed-hitting Massey will hit the bench for the second straight day while the Guardians send another lefty (Logan Allen) to the bump. Massey has played fairly regularly against right-handed pitching since he returned from the injured list Aug. 25, but he might have to settle for more of a part-time role after the Royals got Jonathan India back from the injured list Tuesday.

Vargas is not in the lineup for Wednesday's contest in San Francisco.

Vargas started the previous two games at first base as the Diamondbacks scramble to fill the position following injuries to Pavin Smith (quadriceps) and Tyler Locklear (elbow), but Vargas will take a seat in Wednesday's series finale. Tim Tawa is handling first base and batting eighth as Arizona tries to avoid the sweep.

Gray went 1-for-3 with a solo home run and an additional run scored during Tuesday's 5-4 win over the White Sox.

Gray hit his third home run of the season, tagging Tyler Alexander for a go-ahead solo shot in the seventh inning. It was the 29-year-old's third home run of the campaign. In his last nine games, Gray is 9-for-27 (.333) with three home runs and two doubles.

Wetherholt will return to the lineup at Triple-A Memphis on Wednesday after missing five games with general soreness, Katie Woo of The Athletic reports.

Woo writes that Wetherholt has been dealing with a "non-baseball ailment" but will be back in action at designated hitter Wednesday before returning to the field later this week. Wetherholt is slashing .309/.423/.519 with 16 home runs, 21 stolen bases and a 67:66 K:BB over 100 games this season between Double-A Springfield and Memphis. The top prospect is not expected to be promoted to the majors this month.