Hoskins isn't in the lineup for Sunday's game against the Mariners.

Hoskins will sit down for a second consecutive game after going 3-for-6 with two walks and a run scored over the first two games of the series. Kyle Manzardo will start at first base while Hoskins sits, putting Jose Ramirez in the DH spot and Daniel Schneemann at third base.

Horwitz will start at first base and bat sixth in Sunday's game against the Mets.

Heading into spring training, the 28-year-old's role was somewhat muddled following the offseason additions of Marcell Ozuna, Ryan O'Hearn and Brandon Lowe, but Horwitz looks to have settled into a strong-side platoon role at first base. He's occupied the position for the Pirates' first two games against right-handed pitchers, with O'Hearn spelling him Saturday when the Mets sent lefty David Peterson to the hill.

Clemens will start at first base and bat leadoff in Sunday's game against the Orioles, Aaron Gleeman of The Athletic reports.

After taking a seat against lefty Trevor Rogers in Thursday's season opener, Clemens has now handled the leadoff role in two straight contests against righties. At least for the early part of the season, Clemens looks set to occupy the strong side of a platoon at first base, with Victor Caratini having received the nod at the position in the Twins' lone matchup with a lefty thus far.

Manzardo started a first base and went 1-for-5 with an RBI in Saturday's 6-5 extra-inning win over the Mariners.

Manzardo served as the designated hitter for the first two games of the season before finally getting a chance to play some defense. The Guardians initially planned to give him more starts at first base this season, but for now he's sharing the position with Rhys Hoskins. Manzardo is 2-for-13 with eight strikeouts through three contests.

Murakami went 1-for-3 with a solo home run and a walk Saturday against the Brewers.

Murakami has kicked off his MLB career in style, homering in both of his first two starts. He led off the fourth inning with a home run Saturday, which came after he worked a walk in his initial plate appearance. While it's a small sample, Murakami has struck out only once in eight plate appearances.

Schanuel went 1-for-5 with a three-run home run in Saturday's 11-9 loss to Houston.

It was already the second homer of the young season for Schanuel, who gave the Angels some temporary life in the ninth inning. The 24-year-old had belted 24 long balls over the course of his prior three years in the major leagues (308 games), but he's tapping into his power stroke early in 2026 and should consistently occupy a premium spot in the Halos' lineup throughout the campaign.

Smith went 1-for-4 with a grand slam in Saturday's 6-2 win over the Royals.

Smith played the role of hero Saturday, crushing a walk-off grand slam in his team debut to punctuate Atlanta's six-run comeback in the ninth inning. With Sean Murphy (hip) on the injured list to begin the year and Jurickson Profar suspended for the entire season, the left-handed-hitting Smith has a clear pathway to at-bats at designated hitter versus right-handed pitching for the time being.

Stewart went 2-for-4 with a solo home run, two RBI and a walk in Saturday's 6-5 win over the Red Sox.

Stewart's wrist soreness, which stems from being hit by a 110-mph liner Opening Day, didn't seem to be an issue Saturday, as he stayed hot at the plate. The first baseman had an RBI single in the first inning and then took Sonny Gray deep in the third. Batting cleanup for Cincinnati, Stewart is 5-for-8 with two doubles, one home run and two RBI through two games to begin the regular season.

Hoskins isn't in the lineup for Saturday's game against Seattle.

Hoskins will get a chance to catch his breath after going 3-for-6 with a run scored and a pair of walks over the first two games of the season. His absence will put Kyle Manzardo at first base and open a spot in the lineup for Angel Martinez to start in left field.

The Brewers placed Vaughn on the 10-day injured list Saturday with a hamate fracture in his left hand.

Vaughn made an early exit from Thursday's game against the White Sox after hitting a single in the sixth inning, and imaging revealed a fracture afterwards. He's slated to undergo surgery Monday and will miss roughly 4-to-6 weeks. Jake Bauers and Gary Sanchez will be in the mix for starts at first base while Vaughn is out, and Jeferson Quero will come up from Triple-A Nashville to offer depth at catcher while freeing up Sanchez to occasionally start at first.