Schedule
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| vs | SF 10, CAR 3 - 2nd
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BYE
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Mon, Dec 22
8:15 pm
ESPN
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Now Playing
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0:38MNF Against The Spread: Panthers at 49ers
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0:49MNF Expert Pick: Panthers at 49ers
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1:5549ers Getting Back Healthy; Purdy & Pearsall Returned Last Week
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1:48Christian McCaffrey Playing 1st Game Against Former Team
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1:4349ers Preparing to Move on from WR Brandon Aiyuk
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0:31REPORTS: Aiyuk's 2026 Guaranteed Money Voided By 49ers
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3:25Week 12 NFL Picks: MNF Panthers at 49ers
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1:15Leger Douzable's AFC & NFC Playoff Predictions
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1:41John Breech discusses if the NFC North or NFC West is more likely to get three teams in the playoff
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1:13Cardinals Will Have to Answer Some Big Questions if They Want to Stay Competitive This Season
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0:4849ers Improve to 4-0 Following a Loss This Season
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1:20Purdy Tosses 3 TDs in Return as 49ers Rout Cardinals
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1:24NFL News & Notes: Purdy To Return As 49ers Eye Playoff Push
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1:15Brock Purdy (Toe), Ricky Pearsall Set to Return
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1:34NFL News & Notes: Brock Purdy Set To Return In Week 11
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0:24This Just In: WR Marvin Harrison Jr. (Appendix) Out Vs 49ers
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1:17Week 11 NFL Picks: 49ers at Cardinals
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1:09Predicting the 49ers Final Record
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1:47NFL Playoff Picture: Playoff New Bloods
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7:57NFC West Midseason Grades
Recent Tweets
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Eric Branch@Eric_Branchmoments agoPanthers Pro Bowl CB Jaycee Horn (concussion) has been ruled out. #49ers -
Eric Branch@Eric_Branch9M agoAfter grabbing two of Purdy's three INTs. #49ers https://t.co/0MgvjMOp7D
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Cam Inman@CamInman9M ago49ers defense forces punt to open second half Purdy and Niners offense will start at own 20. Long TV timeout between series has Brock and Mac Jones tossing 25 yard warm-up throws (that's routine; Jones issn't coming in) -
Vic Tafur@VicTafur11M agoI would like to give the 49ers defense some credit but ... -
Cam Inman@CamInman21M agoSome may call it an empanada but I’d like to think 49ers press box is humorously serving turnovers at halftime in honor of three interceptions off Purdy https://t.co/TgxQaAlbmg
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Cam Inman@CamInman27M ago49ers Kyle Shanahan does not rip Brock Purdy for 3 first-half INTs, tells ESPN's Lisa Salters: "Just missed a couple throws. Just let them go a little behind them, a little bit late. Wish he could have those three back. He’s playing good beside those three."
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Niners Nation@NinersNation28M agoThe interceptions were awful. There's no way around that. But equally as impressive was the 49ers' defense holding the Panthers to 3 points. -
Eric Branch@Eric_Branch34M agoHaily Mary for pick No. 4? #49ers
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Vic Tafur@VicTafur36M agoRT @mattbarrows: Sam Okuayinonu's been laboring with what seems to be a bad ankle or foot. The 49ers aren't exactly deep at defensive end.
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Matt Barrows@mattbarrows37M agoSam Okuayinonu's been laboring with what seems to be a bad ankle or foot. The 49ers aren't exactly deep at defensive end.