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Isaiah McDuffie LB | GB
Packers' Isaiah McDuffie: Impresses in starting role
McDuffie recorded nine total tackles (five solo), including 0.5 sacks, and one interception in Sunday's 23-6 win over the Vikings.
With Quay Walker (neck) sidelined for most of the Packers' last two games, McDuffie has seen an expanded role and made the most of it. During that span, he's recorded 20 total tackles, including 1.0 sacks, and one interception, picking off J.J. McCarthy in the fourth quarter of the Week 12 win. If Walker remains out, McDuffie could start alongside Edgerrin Cooper again in the Week 13 matchup against the Lions.
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Max Brosmer QB | MIN
Vikings' Max Brosmer: May draw Week 13 start
Brosmer will take first-team reps at practice to open Week 13 prep with J.J. McCarthy having been placed in the concussion protocol, Ben Goessling of The Minnesota Star Tribune reports.
Brosmer will be in a position to start on the road against Seattle on Sunday if McCarthy is not able to fully clear the NFL's five-step concussion protocol in time to play this weekend. In that scenario, John Wolford would stand to be elevated from the practice squad to operate as Brosmer's backup. The undrafted rookie out of Minnesota has logged four regular-season appearances so far, in which span he's completed five of eight pass attempts for 42 yards.
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Jordan Whittington WR | LAR
Rams' Jordan Whittington: Ties season high for catches
Whittington secured all three targets for 17 yards during Sunday's 34-7 victory against the Buccaneers.
It was another monster game for Puka Nacua and Davante Adams, who combined for 19 targets and a 12-159-2 receiving line. This left little for the other two wideouts who took the field, as, along with Whittington's three targets, Konata Mumpfield mustered just two targets of his own. Whittington's usage crept up again for the second consecutive week, with the second-year pro out on the field for 34 snaps on offense. Tutu Atwell (hamstring) and Xavier Smith (concussion) could both return for the Week 13 contest against the Panthers, however, which would reduce Whittington's already limited role even further.
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J.J. McCarthy QB | NYG
Vikings' J.J. McCarthy: In concussion protocol
Vikings head coach Kevin O'Connell said Monday that McCarthy has been placed in the concussion protocol due to symptoms that manifested after Sunday's loss to the Packers, Alec Lewis of The Athletic reports.
McCarthy's status for Week 13 must now be considered uncertain, as he won't be eligible to retake the field until he's gained full clearance from the NFL's five-step concussion protocol, including from an independent neurologist. O'Connell confirmed that undrafted rookie Max Brosmer will take first-team reps to begin Week 13 preparations, per Ben Goessling of The Minnesota Star Tribune, and start versus the Seahawks on Sunday if McCarthy is unavailable.
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Tyler Guyton OT | DAL
Cowboys' Tyler Guyton: Likely missing Week 13
Guyton is dealing with a high-ankle sprain and likely won't be available for Thursday's matchup against the Chiefs, Todd Archer of ESPN.com reports.
The second-year pro from Oklahoma exited the Week 12 win over the Eagles with an ankle injury and is now expected to be sidelined for the Week 13 matchup as well. While Guyton recovers, Nate Thomas is likely to step in and start at left tackle.
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Shedeur Sanders QB | CLE
Browns' Shedeur Sanders: Officially named Week 13 starter
Coach Kevin Stefanski named Sanders as the Browns' starting quarterback for next Sunday's game against the 49ers.
Even though Dillon Gabriel cleared concussion protocol Monday, Sanders will get the nod against San Francisco after he helped guide the Browns to a 24-10 win over the Raiders on Sunday. Sanders completed 11 of 20 passes (55 percent) for 209 yards, one touchdown and one interception against Las Vegas, showing some deep-ball touch on a 52-yard shot to Isaiah Bond down to the two-yard line in the process. Sanders' matchup against the Niners will be favorable on paper, as San Francisco is dealing with a boat load of injuries on the defensive side of the ball, but it's fair to question if Sanders has enough of a floor-ceiling combo to warrant consideration for fantasy lineups.
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Brian Branch CB | DET
Lions' Brian Branch: Solid performance in Week 12
Branch tallied seven total tackles (three solo) and one pass defensed in Sunday's 34-27 overtime win over the Giants.
The third-year pro from Alabama tied Amik Robertson for the second-most tackles on the Lions defense during Sunday's win, trailing Jack Campbell's 11-stop performance. Branch has appeared in 10 games for the Lions this season, recording 59 total tackles, including 2.5 sacks, and six passes defensed. He's expected to remain one of the team's top defensive playmakers in the Week 13 matchup against the Packers.
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Dillon Gabriel QB | CLE
Browns' Dillon Gabriel: Clears concussion protocol
Gabriel cleared the concussion protocol Monday, Mary Kay Cabot of The Cleveland Plain Dealer reports.
However, Gabriel is expected to lose his starting job to Shedeur Sanders, who is likely to be named the Browns' QB1 for next Sunday's Week 13 game versus San Francisco, according to Ian Rapoport of NFL Network. Gabriel showed very little in his time under center, refusing to challenge defenses deep or away from the line of scrimmage, resulting in 5.1 yards per pass attempt. Across eight games this season, including six starts, Gabriel has completed just 59.2 percent of his 184 pass attempts for 937 yards, seven touchdowns and two interceptions. He's averaged just 117.1 passing yards per game. The Browns now will take a longer look at Sanders to see if either one of the rookies is a viable long-term solution headed into 2026.
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Germaine Pratt LB | IND
Colts' Germaine Pratt: Has 20 tackles in loss
Pratt had 20 total tackles, including two tackles for a loss and a pass defensed in Sunday's loss at Kansas City.
Pratt has been a revelation since taking over a starting linebacker role opposite Zaire Franklin after Joe Bachie went down with an injury and was later released. He played on 83 of the defense's 96 snaps in the overtime loss.
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Blake Corum RB | LAR
Rams' Blake Corum: Meager output in victory
Corum rushed seven times for 24 yards during Sunday's 34-7 victory against the Buccaneers.
While the final score was another blowout win for the Rams, Tampa Bay successfully snuffed out the Rams' rushing attack; Corum and Kyren Williams combined for just 70 yards and no touchdowns on 19 attempts. After seeing double-digit touches for a three-week stretch, Corum's usage has dropped the past two weeks, with just 15 rushing attempts for 34 yards in that span. The Rams travel to take on the Panthers in Week 13, and they have been middle-of-the-road against the run in 2025, surrendering 113.1 yards per game on the ground.