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Andy Isabella WR | SF
Cardinals' Andy Isabella: In line for more work
Isabella is poised for a bigger workload with Christian Kirk (groin) ruled out for Sunday's game against the Lions, Kyle Odegard of the Cardinals' official site reports.
Isabella has earned exactly 14 offensive plays in both of Arizona's first two games of the season, falling short of a 20-percent snap share each time. Following word that Kirk is sidelined this weekend, his 69-percent share has been cleared for the likes of Isabella and KeeSean Johnson to work with DeAndre Hopkins and Larry Fitzgerald in three-wide sets. While Johnson is set to make his season debut Sunday after spending time on the reserve/COVID-19 list, Isabella is coming off a Week 2 performance versus Washington in which he recorded catches of 54 and 13 yards on his pair of targets. The speedster will aim to add a vertical element to the Cardinals offense in the short term.
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Scott Miller WR | CHI
Buccaneers' Scotty Miller: Cleared to play
Miller (hip/groin) doesn't have an injury designation for Sunday's game in Denver.
Miller was a limited practice participant Wednesday and Thursday before upgrading to full at Friday's session. He'll be out there Sunday in Denver, though his fantasy outlook takes a hit with Chris Godwin back in the lineup. Miller was unable to take advantage of his big opportunity last week, catching two of three targets for 11 yards in a 31-17 win over the Panthers.
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JuJu Smith-Schuster WR | NYG
Steelers' JuJu Smith-Schuster: Good to go
Smith-Schuster (knee) doesn't carry an injury designation in advance of Sunday's game against the Texans, Teresa Varley of the Steelers' official site reports.
Smith-Schuster, who didn't practice either Wednesday or Thursday, was back at practice Friday and listed as a full participant. In fact, the Steelers approach the weekend with no players listed with Week 3 injury designations. Smith-Schuster thus is poised to handle his usual pass-catching duties Sunday opposite fellow starter Diontae Johnson. The duo combined for 15 catches on 21 targets in Week 2's win over the Broncos, with Smith-Schuster logging a 7-48-0 stat line off his eight targets. Another busy day figures to be in store for both players versus a Houston squad that's off to an 0-2 start following losses to AFC powerhouses Kansas City and Baltimore.
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Christian Kirk WR | SF
Cardinals' Christian Kirk: Out this week
Kirk (groin) has been ruled out for Sunday's game against the Lions, Darren Urban of the Cardinals' official site reports.
Kirk dropped from 77 percent snap share and five targets in the season opener to 61 percent snap share and four targets Week 2 against Washington. It isn't clear that was related to the groin injury, but we do now know Kirk will miss at least one game. Andy Isabella and Trent Sherfield are the candidates to see snaps alongside DeAndre Hopkins and Larry Fitzgerald in three-wide formations, with Isabella's 4.31 speed making him a better fit for the downfield role Kirk (20.4 aDOT) has been used in this year.
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Jalen Reagor WR | MIA
Eagles' Jalen Reagor: Officially ruled out
Reagor (thumb) has been ruled out for Sunday's game against the Bengals, Martin Frank of The Delaware News Journal reports.
Reagor was able to play through a torn UCL in his right thumb during last week's loss to the Rams, but he'll miss at least one game -- and probably more -- after having surgery Thursday. Ian Rapoport of NFL Network expects the Eagles to place the rookie on injured reserve, which would rule him out for the next three games.
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Brandin Cooks WR | SF
Texans' Brandin Cooks: Clear for Week 3
Cooks (quadriceps) doesn't have a designation for Sunday's contest at Pittsburgh.
Cooks has been hampered by a quad injury each of the first three weeks of the season, only to be available for game days. In the Texans' first two contests, he posted a combined seven catches (on 13 targets) for 115 yards. That said, when he logged 90 percent of the snaps on offense this past weekend against the Ravens, Cooks put up a healthy 5-95-0 line on eight targets. He'll aim to have similar success this weekend against a Steelers defense that has given up 13.7 YPC to wide receivers in 2020.
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A.J. Brown WR | NE
Titans' A.J. Brown: Won't suit up Week 3
Brown (knee) has been ruled out for Sunday's game in Minnesota, Turron Davenport of ESPN.com reports.
After missing yet another week of practice, Brown won't be available for a second consecutive game day due to a bone bruise in his knee. Look for Corey Davis and Adam Humphries to lead the Titans' receiving corps again, with Kalif Raymond filling in on occasion.
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JuJu Smith-Schuster WR | NYG
Steelers' JuJu Smith-Schuster: Practices in full Friday
Smith-Schuster (knee) was a full practice participant Friday, Brooke Pryor of ESPN.com reports.
This comes on the heels of Smith-Schuster not taking any practice reps at all Wednesday and Thursday, before posting on his personal Instagram on Thursday that he expects to play Sunday versus the Texans, according to Ian Rapoport of NFL Network. Still, the Steelers have yet to release Smith-Schuster's game-day availability, which will come out in short order.
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Davante Adams WR | LAR
Packers' Davante Adams: Unlikely to play
Coach Matt LaFleur said Adams (hamstring) is "probably doubtful" for Sunday's game against the Saints, Rob Demovsky of ESPN.com reports.
Adams hasn't practiced at all this week, but the Packers aren't quite ready to rule him out. It sounds like he'll be listed as doubtful on the final injury report, but it's possible the team goes with the 'questionable' designation instead. The Packers and Saints are playing Sunday night.
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Justin Jefferson WR | MIN
Vikings' Justin Jefferson: Should see more targets, eventually
Offensive coordinator Gary Kubiak suggested Jefferson's role should increase as the season progresses, Courtney Cronin of ESPN.com reports. "You're going to see more and more of [Jefferson]," Kubiak said. "But much like Dalvin (Cook), much like Adam, you want to get touches for those type of football players. And with the amount of plays we've been running, touches are hard to come by."
Kubiak is alluding to Minnesota's depressed volume, with the team running an NFL-low 96 plays through two weeks (no other team has fewer than 115). That number will regress to the mean -- at least to some extent -- but it's also true that nobody has stepped up as a viable No. 2 receiving option behind Adam Thielen. Olabisi Johnson is second on the team with seven targets, catching four passes for 80 yards. Jefferson also has been efficient with his limited opportunities (five of six for 70 yards), but his snap share sunk from 69 percent in Week 1 to 54 percent in Week 2, while Johnson went in the other direction (from 63 percent up to 79 percent). In any case, neither makes for a trustworthy fantasy option Week 3 against Tennessee.