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Shane Vereen RB | NO
Giants' Shane Vereen: 20 yards in loss to Jets
Vereen rushed four times for 13 yards and caught two of three targets for seven receiving yards Sunday against the Jets.
Vereen was never expected to make a big impact rushing the ball, but he hasn't done much as a receiver over the last four weeks either, failing to reach even 30 receiving yards. With the Giants splitting the backfield touches between Vereen, Rashad Jennings, Andre Williams and Orleans Darkwa, there's little upside to be seen.
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Ka'Deem Carey RB | CHI
Bears' Ka'Deem Carey: Active for Sunday's game
Carey (concussion) is active for Sunday's game against the 49ers, Rich Campbell of the Chicago Tribune reports.
Meanwhile, fellow backup running back Antone Smith is inactive, meaning Carey will be third string behind Matt Forte and Jeremy Langford for Sunday's game. Carey, who missed last Thursday's matchup with the Packers due to the concussion, is set to notice a decline in touches with Forte now back to full health. While working in a complementary role behind Langford in his last three games, Carey had amassed 116 yards on 30 carries.
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Andre Ellington RB | TB
Cardinals' Andre Ellington: Could miss Week 14
Ellington (toe), who has been ruled out for Sunday's game against the Rams, could also miss next Thursday's game against the Vikings, according to ESPN's Adam Schefter.
Ellington is reportedly set to meet with a specialist to examine his turf toe, and with the quick turnaround to the Thursday night game, it won't be nearly enough time to get him healthy enough to play. With Chris Johnson (knee) also out, David Johnson is expected to start in their place, with Stepfan Taylor and Kerwynn Williams getting the backup touches.
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DuJuan Harris RB | JAC
Seahawks' DuJuan Harris: Promoted from practice squad
Harris was promoted from the Seahawks' practice squad Saturday, ESPN's Adam Caplan reports.
Harris is expected to provide some depth at the running back position with Marshawn Lynch (hernia surgery) sidelined, but he's unlikely to become a fantasy contributor unless Thomas Rawls and Fred Jackson sustain injuries.
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Shaun Draughn RB | NYG
49ers' Shaun Draughn: Set to start again
Draughn's teammate Carlos Hyde (foot) has been ruled out for Sunday's game in Chicago.
Draughn thus figures to handle another heavy workload, after playing every single offensive snap in a Week 12 loss to the Cardinals. He had exactly 20 touches in each of the last three games, as the 49ers don't seem to have much faith in their other backup running backs. The Chicago defense is allowing 4.8 yards per carry and 128.5 rushing yards per game this season.
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Ka'Deem Carey RB | CHI
Bears' Ka'Deem Carey: Probable to face Niners
Carey (concussion) is listed as probable for Sunday's game against the 49ers, CSN Chicago's Chris Boden reports.
Carey made it through the concussion protocol and logged full practices throughout the week, but with Matt Forte and Jeremy Langford both healthy, Carey will merely serve as the No. 3 running back. There's a good chance he won't play any offensive snaps in Sunday's game.
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Andre Ellington RB | TB
Cardinals' Andre Ellington: Visiting with specialist
Ellington (toe), who has been ruled out for Week 13, will see a specialist to evaluate his turf toe, Mike Jurecki of FOX Sports 910 Phoenix reports.
Recovery from turf toe is unpredictable and Ellington's injury track record is far from encouraging. While that doesn't mean a multi-week absence should be assumed, it is clear that Ellington's no lock to be ready for Week 14, in addition to be already being ruled out for Sunday's game against the Rams. David Johnson is set to lead the Arizona backfield Sunday afternoon, with Stepfan Taylor and Kerwynn Williams working in relief.
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Andre Ellington RB | TB
Cardinals' Andre Ellington: Ruled out for Week 13
Ellington (toe) has been ruled out for Sunday's game in St. Louis.
As expected, Ellington will miss at least one game due to the turf toe injury he suffered in Week 12. David Johnson is thus set to serve as the unquestioned leader of Arizona's backfield in Sunday's game, but with Chris Johnson done for the season, Ellington may still get his shot at an increased role. David Johnson will be backed up by Stepfan Taylor and Kerwynn Williams.
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Mike Gillislee RB | NE
Bills' Mike Gillislee: Will join Bills' active roster
Gillislee will be promoted to the Bills' active roster prior to Sunday's game against the Texans, Mike Rodak of ESPN.com reports.
Gillislee will be brought up from the Bills' practice squad with Karlos Williams (shoulder) out this week. He will work as the team's third running back behind LeSean McCoy and Anthony Dixon.
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Ryan Mathews RB | PHI
Eagles' Ryan Mathews: Will not play in Week 13
Mathews (concussion) has been ruled out for Sunday's game against the Patriots.
Mathews has not been able to escape the league's concussion protocol as of yet, so he will sit out for the third week in a row. He still needs to be cleared, but he is able to exercise without concussion symptoms, according to Les Bowen of the Philadelphia Daily News, so he could have a chance to return to action in Week 14.