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Jacquizz Rodgers RB | NO
Buccaneers' Jacquizz Rodgers: Extended action after Martin injury
Rodgers rushed eight times for 30 yards and secured one of two targets for six yards in Sunday's 34-20 loss to the Falcons. He also returned two kickoffs for 43 yards.
With Doug Martin exiting in the first half with a possible concussion, Rodgers saw his most extensive playing time since Week 4 against the Giants, the last game of the former's suspension. The 27-year-old had not logged more than three carries in any subsequent contest, but he could be in line for an expanded opportunity once again in Week 13 versus the Packers if Martin is unable to return for that game.
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Damien Williams RB | ARI
Dolphins' Damien Williams: Likely headed for extended absence
Williams (shoulder) likely will miss extended time, James Walker of ESPN.com reports.
Williams was removed from Sunday's 35-17 loss to the Patriots after injuring his shoulder in the third quarter. Kenyan Drake handled all the backfield work from that point forward, as No. 3 back Senorise Perry (concussion) had already left the game and been ruled out for the rest of the day. Given that Williams and Drake had been splitting work since Jay Ajayi was traded, Sunday's series of events could open up a major opportunity for Drake, a 2016 third-round pick who has mostly proven to be explosive but not reliable.
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Alvin Kamara RB | NO
Saints' Alvin Kamara: Drops 188 yards, two scores on Rams
Kamara rushed five times for 87 yards and one touchdown while securing all six of his targets for 101 yards and another touchdown during Sunday's 26-20 loss to the Rams.
In the past 25 years, no running back with at least 100 touches has averaged over eight yards per touch, according to NFL Research. Kamara, who's now seen the ball 131 times, is boasting a gaudy 8.35 mark through 11 games. The Tennessee product is truly putting together a prolific rookie campaign and even outshone starter Mark Ingram on Sunday, though it can't be ignored that game flow dictated a more pass-heavy approach that naturally favors Kamara's strengths. By all likelihood, the Saints will continue to feature both tailbacks in the gameplan moving forward in a way where both Kamara and Ingram see a healthy dose of opportunities on a game-by-game basis. However, next week's matchup with a Panthers team allowing just 3.9 yards per carry figures to work in Kamara's favor.
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Derrick Henry RB | BAL
Titans' Derrick Henry: Churns out 79 rushing yards in win
Henry rushed 13 times for 79 yards while catching one of two targets for 10 yards in Sunday's 20-16 win at Indianapolis.
Henry accounted for 52 of his team's 77 yards on the go-ahead drive in the fourth quarter only to see DeMarco Murray vulture a one-yard touchdown at the end. The second-year running back also sealed the win with a 16-yard run for a first down inside the two-minute warning and ended up with 70 more rushing yards than Murray on one more carry. Murray remains the bigger receiving threat, but the duo is approaching a 50-50 split on the ground.
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Christian McCaffrey RB | SF
Panthers' Christian McCaffrey: Tallies 97 yards
McCaffrey ran for 62 yards on seven carries and added 35 yards on two catches in Sunday's 35-27 win over the Jets.
The bulk of McCaffrey's work came late in the second quarter on a 40-yard run that set up a Panthers field goal. McCaffrey entered the game with three touchdowns in his previous two games and so fans might have, understandably, hoped for more. Still, it's hard to expect much from the rookie considering how relatively few touches he's garnered, with just two games of 15 or more this season. Few all-purpose backs can do what McCaffrey does in terms of piling up yardage on 10 to 12 touches per game, but the backfield is still crowded with Jonathan Stewart and Cam Newton no matter how unique McCaffrey's skill set is.
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Kerwynn Williams RB | KC
Cardinals' Kerwynn Williams: Injures rib Sunday
Williams is questionable to return to Sunday's contest against the Jaguars due to a rib injury, Mike Jurecki of Arizona Sports 98.7 FM reports.
Before his departure, Williams totaled eight yards on three carries while taking two punt returns for a combined 22 yards. If he doesn't return, D.J. Foster will be the top candidate to receive work behind No. 1 running back Adrian Peterson.
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Raheem Mostert RB | LV
49ers' Raheem Mostert: Will not return Sunday
Mostert is out for the remainder of Sunday's game against Seattle with a knee injury,Matt Maiocco of NBC Sports Bay Areareports.
The injury leaves San Francisco without its third-string running back or kick returner. Trent Taylor, who normally returns punts, will probably fill in for Mostert on kickoffs.
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Corey Clement RB | ARI
Eagles' Corey Clement: Makes most of five touches
Clement gained 27 yards on four carries and 12 yards on one reception in Sunday's 31-3 win over the Bears.
Clement hasn't disappeared from the offense despite the emergence of Jay Ajayi as an effective complement to LeGarrette Blount. The team clearly thinks highly of its rookie back, and it's telling that Clement got each of his five touches prior to garbage time in the fourth quarter. He's essentially stuck in a role as the third part of a three-headed monster, but there's little question the Eagles would have faith in Clement if injuries higher up the depth chart pushed him into a larger role. He'll take aim at the Seahawks in Week 13.
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Joe Mixon RB | HOU
Bengals' Joe Mixon: Notches first career 100-yard rushing performance
Mixon rushed 23 times for 114 yards and a touchdown in Sunday's 30-16 win over the Browns. He also reeled in all three passes directed his way for 51 yards.
Mixon had gains of nine and 19 yards on the Bengals' opening drive and seemingly made chunk plays at will in the contest, including three of 11 or more yards on the drive that culminated in his touchdown run. It was seemingly just a matter of time before the rookie would break out, as he has now run the ball more than 20 times in back-to-back games. He has another stiff test against Pittsburgh in Week 13.
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Cordarrelle Patterson RB | PIT
Raiders' Cordarrelle Patterson: Suits up Sunday
Patterson (hip) is listed as active for Sunday's game against the Broncos.
Patterson remains behind Amari Cooper and Michael Crabtree in the Raiders' wideout pecking order, so he's only an option in deeper formats. His 45-yard output in Week 11's loss to the Patriots represented his season high, and overall, Patterson has logged just 18 catches for 114 yards through 10 games to date.