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Kenyan Drake RB | GB
Dolphins' Kenyan Drake: Suffers shoulder injury
Drake was forced out of Sunday's game against the Packers with a shoulder injury, Adam H. Beasley of the Miami Herald
Prior to his exit from the contest, Drake ran four times for 15 yards and caught one pass for three yards. In his absence, added backfield touches are available for Frank Gore and Kalen Ballage.
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Marlon Mack RB | ARI
Colts' Marlon Mack: Makes minimal impact versus Jaguars
Mack carried 12 times for 29 yards and caught two passes for an additional nine yards during Sunday's 29-26 win over the Jaguars.
Mack received the majority of the touches out of the backfield, but he never got it going on the ground as he averaged just 2.4 yards per carry. He also made a minimal impact as a pass catcher, and his only really notable play of the day came on a successful two-point conversion in the second quarter. While the matchup wasn't ideal, this performance is even more disappointing for Mack's owners when considering he'd racked up 401 scrimmage yards and four touchdowns over his last three games. It remains to be seen if his recent foot injury limited him in this one, but he'll try to bounce back next Sunday against the Titans.
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Joe Mixon RB | HOU
Bengals' Joe Mixon: Production curtailed by game flow
Mixon was effective when used Sunday against the Saints, carrying the ball 11 times for 61 yards to go along with two catches for 24 yards.
Unfortunately for Mixon, the Bengals were getting blown out, so running opportunities after the second quarter were scarce. The Bengals next travel to Baltimore, where the game at least figures to be closer, even if the matchup isn't great for Mixon.
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Alvin Kamara RB | NO
Saints' Alvin Kamara: Scores twice in big win
Kamara ran for 56 yards and two touchdowns on 12 carries and added 46 yards on four receptions during Sunday's 51-14 win over the Bengals.
Known mostly as a speedster, Kamara showed his versatility on two second-quarter touchdown runs against the Bengals. First, he bruised through the heart of Cincinnati's defense for a four-yard touchdown. Then, on the very next drive, he used his speed to beat the defense to the edge on a one-yard toss play. The sophomore back has now scored multiple touchdowns in three straight games. Though Mark Ingram's big day might be a cause for concern in most backfields, the dependence the Saints have on their backs in the passing game likely means that there are plenty of touches to go around. Up next in Week 11 is a mediocre Philadelphia run defense surrendering 4.5 yards per carry.
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Nick Chubb RB | HOU
Browns' Nick Chubb: Scores 92-yard TD in win
Chubb rushed 20 times for 176 yards and a touchdown while catching all three of his targets for 33 yards and another touchdown in Sunday's 28-16 win over the Falcons.
Chubb caught a 13-yard score in the final minute of the first half, then exploded for the longest offensive touchdown in the league this season on a 92-yard scoring scamper in the third quarter. The rookie second-rounder is quickly making a name for himself in a starting role, but owners will have to look elsewhere at the running back position in Week 11 with Cleveland on bye.
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Samaje Perine RB | CIN
Redskins' Samaje Perine: Active again Sunday
Perine is active for Sunday's contest at Tampa Bay.
Perine has been called upon this season during Chris Thompson's (ribs) three absences, and he'll do the same Week 10. In those outings, Perine accrued 30 yards from scrimmage on eight touches. With Adrian Peterson and Kapri Bibbs in front of him, Perine can't be expected to receive more than a handful of looks, barring an injury to one of the pair.
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Kenjon Barner RB | TB
Patriots' Kenjon Barner: Inactive Sunday
Barner is inactive for Sunday's game against the Titans.
Barner is the odd man out, with Sony Michel back from a knee injury. Meanwhile, James White is on hand to assume change-of-pace/pass-catching duties, while versatile wideout Cordarrelle Patterson is on hand in the event that Michel suffers any in-game setbacks Sunday.
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Mark Walton RB | MIA
Bengals' Mark Walton: Likely in line for role reduction
Walton is active for Sunday's game against the Saints, but he's expected to see reduced involvement on offense with Giovani Bernard (knee) returning from a four-game absence, Fletcher Page of The Cincinnati Enquirer reports.
Walton had functioned as the Bengals' clear backup running back with one of Bernard or Joe Mixon missing each of the last six games, but that role didn't bear much fruit. Over that span, Walton managed just 24 yards on 13 carries and hauled in five receptions for 41 yards. Though he'll continue to dress Sunday, Walton's snap count on offense will likely sink into the single digits, with the rookie instead expected to see most of his action on special teams.
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Cordarrelle Patterson RB | PIT
Patriots' Cordarrelle Patterson: On track to resume previous role
With Sony Michel (knee) back in action, Patterson is in line to resume his normal reserve wideout/return duties Sunday against the Titans.
The versatile wideout helped fill in for Michel out of the New England backfield over the last couple of weeks, but as long as Michel avoids any in-game setbacks, Patterson's workload will dip in Week 10. Patterson remains dangerous in the return game and capable of breaking off the occasional big play when the coaching staff finds ways to get the ball into his hands, but he's a fantasy roll of the dice in his standard role, which he'll return to Sunday.