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Dare Ogunbowale RB | LV
Jaguars' Dare Ogunbowale: Inactive Week 12
Ogunbowale (hand) is inactive for Sunday's game against Cleveland.
Ogunbowale was considered questionable with the hand injury but will be unavailable for Sunday's contest. Devine Ozigbo will operate as Jacksonville's secondary running back, though James Robinson should once again dominate the backfield work.
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Qadree Ollison RB | PIT
Falcons' Qadree Ollison: Scratched for Week 12
Ollison (coach's decision) is inactive for Sunday's game against the Raiders.
Todd Gurley (knee) is inactive, and instead of responding with an increased role for Ollison, the Falcons made him a healthy scratch. Tony Brooks-James was elevated from the practice squad to add depth behind Brian Hill and Ito Smith.
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Austin Ekeler RB | WAS
Chargers' Austin Ekeler: Could share work in return
Ekeler (hamstring) will play in Sunday's game against the Bills after being activated from injured reserve, but the Chargers aren't expecting him to fill a bell-cow role in his first game since Week 4, Ian Rapoport of NFL Network reports.
Though Ekeler is believed to be fully healthy again after missing two months with the serious hamstring injury, he only resumed practicing with the Chargers this week. With that in mind, the Chargers may be inclined to take a cautious approach with the 25-year-old, who played 65.1 percent of the team's offensive snaps and averaged 21 touches over his first three outings of the season before getting hurt. Top backup Kalen Ballage (ankle/calf) is viewed as game-time decision for Sunday, so Joshua Kelley or Troymaine Pope would be next in line to rotate in behind Ekeler if Ballage can't go.
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Boston Scott RB | PIT
Eagles' Boston Scott: Green light for MNF
Scott (abdomen) won't carry an injury designation into Monday's game against the Seahawks.
Scott upgraded to full participation at Saturday's practice, so he's full speed ahead for Monday's primetime matchup. Miles Sanders is healthy and remains the clear lead back. Scott has still received plenty of work on offense with Sanders in the equation, as he played 40 percent of the offensive snaps in last week's win against the Browns, producing 50 yards on eight touches.
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Craig Reynolds RB | WAS
Jaguars' Craig Reynolds: Promoted ahead of Week 12
The Jaguars signed Reynolds to the active roster Saturday.
Chris Thompson (back) remains on IR, and Dare Ogunbowale (hand) is considered questionable. Reynolds will add depth in the backfield as a result. Rookie James Robinson is still the clear bell cow, so Reynolds' duties will be reserved for special teams.
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Royce Freeman RB | CHI
Broncos' Royce Freeman: May see some QB work
Freeman could play at quarterback in Sunday's game against the Saints following news that every Broncos QB is in COVID-19 protocol, Mike Klis of 9News Denver reports.
Freeman is the Broncos' emergency quarterback. The Broncos are also expected to elevate Kendall Hinton from the practice squad. Hinton played some quarterback in college before switching to wide receiver at the start of his junior year at Wake Forest. The Broncos will need to get creative under center, and perhaps Freeman will take snaps in a wildcat formation. He could see a bump in usage as a result, although it's tough to get a grasp on how things will ultimately shake out for the Broncos.
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Jeff Wilson RB | MIA
49ers' Jeff Wilson: Lifted from IR
Wilson (ankle) was activated from injured reserve Saturday and is questionable for Sunday's game against the Rams, Jennifer Lee Chan of NBC Sports Bay Area reports.
Raheem Mostert (ankle) was also activated and handed a questionable designation for Week 12. Meanwhile, Tevin Coleman (knee) has been ruled out. Jerick McKinnon is the only fully healthy, experienced running back heading into Sunday's game. It's a fool's errand to project how the backfield reps will be divvied up, but Wilson may be the odd man out if Mostert is at 100 percent.
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Raheem Mostert RB | LV
49ers' Raheem Mostert: Activated from IR
Mostert (ankle) was activated from injured reserve Saturday.
Coach Kyle Shanahan stated Friday that this transaction would happen, adding that Mostert is still considered questionable for Sunday's game against the Rams. Jeff Wilson (ankle) is in the same boat, while Tevin Coleman (knee) has been ruled out. Mostert figures to capture a bulk of the backfield work if he plays Sunday in a tough road matchup against the Rams.
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Matt Breida RB | SF
Dolphins' Matt Breida: More work on tap
Breida is expected to be the Dolphins' primary running back after Myles Gaskin (knee) and Salvon Ahmed (shoulder) were ruled out for Sunday's matchup against the Jets, Cameron Wolfe of ESPN.com reports.
There was some hope Gaskin would be activated off injured reserve following his minimum three-game stint, but the team is evidently content allowing Breida to act as the primary ball carrier for at least this Sunday against the Jets. The 25-year-old has seen more than six carries just twice this season and sports a paltry 3.4 yards-per-carry across 39 totes this year, but this figures to be a solid matchup regardless considering the Jets' porous defense. Breida could even be a factor in the passing game, particularly with Ryan Fitzpatrick likely set to start behind center after Tua Tagavailoa (left thumb) was downgraded to doubtful.
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Myles Gaskin RB | SEA
Dolphins' Myles Gaskin: Not playing Sunday
Gaskin (knee) will not play Sunday after the running back was not activated off injured reserve in time to be eligible to play in the contest, Cameron Wolfe of ESPN.com reports.
There was some thought Gaskin could play after serving his mandatory three-game stint on injured reserve, but Saturday's lack of announcement means he'll be unable to play Sunday against the Jets. With Salvon Ahmed (shoulder) also ruled out, Matt Breida will step into the starting role with Patrick Laird and DeAndre Washington expected to chip in as complementary pieces.