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Godwin Igwebuike RB | PIT
Lions' Godwin Igwebuike: Three touches sans Swift
Igwebuike rushed twice for eight yards while catching one of two targets for 13 yards during Sunday's 29-27 win over the Vikings.
Igwebuike saw an uptick in offensive snaps with D'Andre Swift (shoulder) sidelined, but he didn't do much before the final minutes of the game. He'll remain irrelevant in most fantasy formats even if Swift remains sidelined in Week 14 against Denver.
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Khalil Herbert RB | SF
Bears' Khalil Herbert: Minimal work in loss
Herbert rushed four times for 16 yards and caught his only target for 11 yards in the Bears' 33-22 loss to the Cardinals on Sunday.
Herbert's 27 yards were five more yards than he had in the last three games combined since David Montgomery returned to the lineup in Week 9. Unless Montgomery misses more time, Herbert's likely to have very limited fantasy value.
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Cordarrelle Patterson RB | PIT
Falcons' Cordarrelle Patterson: Rushing success in tough matchup
Patterson rushed 13 times for 78 yards and brought in three of five targets for 18 yards in the Falcons' 30-17 loss to the Buccaneers on Sunday. He also recovered a fumble.
Patterson surprisingly found some success against the Buccaneers' typically impenetrable run defense, though a bulk of his production came on a 39-yard run. Nevertheless, it was Patterson's saving grace from a fantasy perspective and served as his second-highest rushing yardage tally of the season. The versatile veteran's next opportunity to wreak havoc on a defense comes in a Week 14 visit to the division-rival Panthers.
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Saquon Barkley RB | PHI
Giants' Saquon Barkley: Held to 74 total yards
Barkley recorded 11 carries for 55 yards in Sunday's 20-9 loss to the Dolphins. He added six receptions on nine targets for 19 yards.
The Giants ran the ball only 17 times while taking to the air on 44 occasions. As a result, Barkley's primary opportunity to produce came through the air, and he was able to rack up six receptions for the third time this season. He also displayed some burst as a runner, turning in two rushes that went for double-digit yards. His longest carry went for a gain of 23, which was only his third rush of 20 yards or more on the campaign. On a bit more of an optimistic note, Barkley has earned 17 total touches in consecutive games heading into a Week 14 matchup against the Chargers.
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Kenyan Drake RB | GB
Raiders' Kenyan Drake: Exits Sunday's game
Drake injured his ankle during Sunday's game against Washington.
With Drake ruled out for the remainder of the contest and Jalen Richard (reserve/COVID-19 list) unavailable, Peyton Barber is on hand to spell lead back Josh Jacobs. Prior to his injury, Drake logged one carry for no gain and caught one of his two targets for eight yards.
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Joe Mixon RB | HOU
Bengals' Joe Mixon: Hurts neck in Week 13 loss
Mixon revealed after Sunday's 41-22 loss to the Chargers that he hurt his neck during the game, Kelsey Conway of The Cincinnati Enquirer reports.
The running back was still able to log 19 carries for 54 yards and a TD (with a lost fumble) in the contest, but it will still be worth monitoring his status as next Sunday's game against the 49ers approaches. If Mixon ends up missing any practice time, Samaje Perine would be next up for the team's running back reps.
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Alexander Mattison RB | MIA
Vikings' Alexander Mattison: Produces strong results as expected
Mattison rushed 22 times for 90 yards and a touchdown while adding three receptions for 34 yards in Sunday's 29-27 loss to the Lions.
Mattison got the start in place of the injured Dalvin Cook (shoulder), doing his best impression of Minnesota's star tailback. The 23-year-old is now averaging 149.3 combined yards and two total touchdowns in the three starts he has made this season, making him a must-roster player for any games Cook is forced to miss. While the latter was technically listed as questionable leading up to Sunday's tilt, initial reports projected Cook to miss two games. The Vikings are slated to take on the Steelers on Thursday, so Mattison could get another start with such a quick turnaround.
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Jermar Jefferson RB | MIN
Lions' Jermar Jefferson: Small role in Swift's absence
Jefferson rushed five times for 18 yards while failing to catch his lone target during Sunday's 29-27 win over the Vikings.
Jefferson technically saw an expanded role with D'Andre Swift (shoulder) sidelined, but he still took a clear backseat to Jamaal Williams, who commanded 18 touches. While it's possible that Swift misses another game in Week 14 against the Broncos, do not bet on Detroit splitting the backfield reps between Jefferson and Williams like they do between a Williams and a healthy Swift.
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Jamaal Williams RB | NO
Lions' Jamaal Williams: Totals 80 yards in Swift's absence
Williams rushed 17 times for 71 yards while catching his only target for nine yards during Sunday's 29-27 win over the Vikings.
While Williams clearly operated as the lead running back in the absence of D'Andre Swift (shoulder), he was hardly used as a receiver after seeing five targets in Swift's absence last week. However, the fact that Detroit surprisingly played with a two-score lead for parts this game probably played a role in that development. With Swift seemingly in line to miss a second game in Week 14 against Denver, look for Williams to get another huge workload with more upside as a receiver than he showed against Minnesota.
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Miles Sanders RB | DAL
Eagles' Miles Sanders: Re-injures ankle Sunday
Sanders relayed after Sunday's 33-18 road win against the Jets that he re-injured the ankle that has bothered him since a Week 8 game at Las Vegas, Dave Zangaro of NBC Sports Philadelphia reports.
Sanders was forced out in the fourth quarter Sunday after hurting his right ankle at the end of a third-down catch. Prior to his exit, he paced the Eagles backfield with 24 carries for 120 yards and also hauled in all three targets for 22 yards. The original injury forced a stint on injured reserve, but with the team heading into a Week 14 bye the running back is confident he'll be ready once Philadelphia next plays Sunday, Dec. 19 against Washington. Sanders joins Jordan Howard (knee) as injured Eagles running backs, leaving Boston Scott and Kenneth Gainwell as the healthiest at the position on the team's active roster.