The Orioles designated Rodriguez for assignment Tuesday.

The Orioles needed to create roster space with Jorge Mateo (hamstring) and Tyler Wells (elbow) returning from the 60-day injured list, so Rodriguez will be jettisoned from the 40-man alongside Corbin Martin. Rodriguez has posted an unsightly 9.15 ERA and 1.68 WHIP over 19.2 innings between Milwaukee and Baltimore this season, making it unlikely that another team targets him on waivers.

The Orioles reinstated Wells (elbow) from the injured list prior to his start Tuesday against the Padres.

Wells will make his season debut Tuesday after spending the year recovering from the UCL revision and brace augmentation procedure he underwent last June. The 31-year-old posted a 2.49 ERA and 1.11 WHIP alongside a 24:6 K:BB over 25.1 innings during his six rehab starts, and he built up to 6.1 frames during his most recent outing.

The Orioles optioned Handley to Triple-A Norfolk on Tuesday, Rich Dubroff of BaltimoreBaseball.com reports.

Handley was recalled from Norfolk on Monday, but he did not see the field. The catcher getting optioned corresponds with Tyler Wells (elbow) and Jorge Mateo (hamstring) both being reinstated from the 60-day injured list Tuesday.

The Orioles reinstated Mateo (hamstring) from the injured list Tuesday.

Mateo initially landed on the injured list in June with a left elbow injury, but his time on the shelf was extended by a couple of months after he strained his left hamstring during a rehab game at Triple-A Norfolk. Now fully recovered from both injuries, the 30-year-old utility man will rejoin the active roster and likely take on a bench role, though his defensive versatility will boost his odds of cracking the starting nine occasionally. With Tyler Wells (elbow) also returning from the 60-day IL on Tuesday, Corbin Martin and Elvin Rodriguez were DFA'd to make room on the 40-man roster.

Clement is out of the lineup for Tuesday's game against the Reds.

Clement started the past two games after missing some time due to a hairline finger fracture and a shin laceration, and he'll get a breather after going 2-for-8 with an RBI and a run. Isiah Kiner-Falefa, who was claimed off waivers over the weekend, will make his season debut for Toronto at third base.

Seymour isn't in the lineup for Tuesday's game against the Mariners, Marc Topkin of the Tampa Bay Times reports.

Seymour will grab a seat on the bench for a second consecutive game after having started the Rays' previous two contests. Yandy Diaz will cover first base instead Tuesday while Richie Palacios serves as the DH.

Barger is not in the lineup for Tuesday's game against the Reds.

Barger started the previous six games but will take a seat Tuesday after going 4-for-22 with a double, two RBI and eight strikeouts during that span. Nathan Lukes will shift to right field, which opens up left field for Davis Schneider.

The Tigers removed Paddack from the rotation Tuesday and will deploy him out of the bullpen moving forward, Evan Woodbery of MLive.com reports.

The right-hander's demotion to the bullpen comes after he submitted a 5.40 ERA, 1.20 WHIP and 14:5 K:BB over 30 innings since the Tigers acquired him from the Twins on July 28. Paddack will give up his spot in the rotation to Sawyer Gipson-Long, who was called up from Triple-A Toledo to start Tuesday's game versus the Mets.

The Blue Jays recalled Pina from Triple-A Buffalo and placed him on the 60-day injured list Tuesday with a right elbow UCL sprain.

The move clears a spot on the 40-man roster for the addition of Ryan Borucki. Pina hasn't pitched since the beginning of August and will not return this season, although at this point it appears he will not have surgery.

The Blue Jays optioned Lucas to Triple-A Buffalo on Tuesday.

Lucas has been roughed up for 18 runs over 24.1 frames with Toronto this season. He's being replaced on the roster and in the bullpen by Ryan Borucki.