Mountcastle is out of the lineup for Wednesday's game against the Rangers.

Mountcastle has found playing time difficult to come by in the early going; he's started just once in the Orioles' first six games and has logged five plate appearances in total. With Samuel Basallo serving as the Orioles' primary designated hitter and offseason pickup Pete Alonso handling an everyday role at first base, Mountcastle likely won't have a path to steady at-bats unless either of the former two players misses time at some point.

O'Hearn is not in the lineup for Wednesday's contest in Cincinnati.

The left-handed-hitting O'Hearn was in the lineup the first two times the Pirates faced a lefty this season, but he'll take a seat in Wednesday's series finale as the Reds send southpaw Andrew Abbott to the hill. Jake Mangum will cover right field and Spencer Horwitz will handle first base for the Pirates.

Kurtz is not in the lineup for Wednesday's game in Atlanta.

Kurtz will receive his first day off of the season after going 1-for-17 with 11 strikeouts through five games. Andy Ibanez will get a start at first base and bat second as the Athletics take on lefty ace Chris Sale at Truist Park.

Crim (oblique) went 1-for-3 with a single in his first rehab game with Triple-A Albuquerque on Tuesday.

Crim missed most of Cactus League action with a strained oblique but has been deemed ready to play in games again. It's essentially the start of spring training for Crim, so his rehab assignment could be a lengthy one and he's not a given to rejoin the major-league roster at the end of the assignment.

Guerrero went 2-for-3 with two walks, an RBI and a run scored during the Blue Jays' 5-1 win over the Rockies on Tuesday.

Guerrero gave the Blue Jays a 2-0 lead in the fifth after drawing a bases-loaded walk, and he was brought home in the seventh on a Nathan Lukes RBI single. Guerrero has yet to record an extra-base hit through five regular-season games, though he's reached base safely in 12 of 22 plate appearances to open the 2026 campaign.

Kayfus isn't in the lineup for Tuesday's game against the Dodgers.

Kayfus has yet to record his first hit of the season through 11 plate appearances, and he'll take a seat Tuesday with Shohei Ohtani on the mound for Los Angeles. Angel Martinez will fill the resulting void in left field and bat ninth.

Polanco isn't in the lineup for Tuesday's game against the Cardinals.

Manager Carlos Mendoza said Monday that Polanco has been dealing with a sore Achilles, and the 32-year-old infielder will now get a chance to rest after opening the series with a 2-for-5 performance. Jared Young will pick up a start at first base as a result and bat fifth.

Vaughn underwent successful left hamate bone surgery Monday, Adam McCalvy of MLB.com reports.

Vaughn suffered the injury Opening Day and landed on the 10-day injured list Saturday after tests revealed a fracture. The Brewers hope he will be ready to return around mid-May. Jake Bauers and Gary Sanchez will handle first base for the Brewers while Vaughn is sidelined.

Steer is not in the lineup for Tuesday's game against the Pirates.

Steer is just 1-for-13 at the plate to start the season, so he'll get a day to regroup. Will Benson is handling left field and batting sixth in Steer's stead.

Santana started at first base and went 0-for-3 with a walk in Monday's 9-6 win over the Tigers.

Santana was in the lineup against a right-hander after Pavin Smith (elbow) was placed on the 10-day injured list Monday. The switch-hitting Santana, in theory, could start against pitchers of either hand, but it's uncertain how manager Torey Lovullo wants to handle first base going forward without Smith. Tim Tawa and Ildemaro Vargas are also options. Santana is 1-for-12 through four games played in the regular season.