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Jalen Guyton WR | LV
Chargers' Jalen Guyton: Listed as questionable for Week 12
Guyton (groin) is listed as questionable for Sunday's game against the Ravens after being a limited participant in practices this week.
After sitting out the Chargers' Week 11 loss to the Packers, Guyton seemingly has a better chance to play this Sunday after he was able to practice this week, albeit in a limited capacity. Ideally for those considering him in Week 12 fantasy lineups, more clarity regarding Guyton's status will come well before the Chargers and Ravens kick off at 8:20 p.m. ET. If Guyton is available, he'll have an opportunity to reclaim a key role in a Chargers' wideout corps that also includes top option Keenan Allen and 2023 first-round pick Quentin Johnston. In his last outing Nov. 12 against the Lions, Guyton logged a 79 percent snap share en route to catching four of his six targets for 41 yards and a touchdown.
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Odell Beckham Jr. WR | MIN
Ravens' Odell Beckham: Listed as questionable
Beckham (shoulder) is listed as questionable for Sunday's game at the Chargers despite upgrading to full practice participation Friday.
The same goes for WR Zay Flowers, who told reporters his hip injury isn't a real threat to his availability Sunday night. Beckham acknowledged his own shoulder injury is more of a concern, calling himself a game-time decision, though he was optimistic about ultimately playing and now has closed out the week with a full practice. The Ravens will need more from their wide receivers in general, including Sunday night, after losing TE Mark Andrews to a season-ending leg injury. Nelson Agholor and Rashod Bateman could end up startable in deeper leagues if Beckham or Flowers is inactive come Sunday night.
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Zay Flowers WR | BAL
Ravens' Zay Flowers: Questionable despite full practice
Flowers (hip) was a full practice participant Friday but is listed as questionable for Sunday's game at the Chargers.
Flowers already downplayed his absence from practice Thursday and told reporters his availability for Sunday has never been in doubt, per Jamison Hensley of ESPN.com. A full practice to close out the week confirms the rookie is on track to play, though the Ravens will leave the door open for a last-second change of heart or setback. Fellow wideout Odell Beckham (shoulder) also is listed as questionable for Sunday night's game despite upgrading to full practice participation Friday.
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Justin Jefferson WR | MIN
Vikings' Justin Jefferson: Remains limited in practice
Jefferson (hamstring) was a limited practice participant Friday and said he's not sure if he will play Monday against the Bears, Kevin Seifert of ESPN.com reports.
Jefferson said his recovery is going well and noted that he's been clocked at top speeds during practice, but he also reiterated that he and the team are on the same page about taking a cautious approach. He's been listed as limited for every practice since the Vikings designated him Nov. 8 to return from injured reserve -- a move that opened a three-week window to activate Jefferson to the roster. The window closes a few days after Minnesota's Week 12 contest, so any transaction returning Jefferson to the roster in the upcoming days would suggest he's expected to play Monday night.
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DeVante Parker WR | PHI
Patriots' DeVante Parker: Questionable for Sunday's contest
Parker (concussion) is listed as questionable for Sunday's game against the Giants after being limited in practice this week.
Parker hasn't seen game action since Week 8, but in the wake of the Patriots' Week 11 bye and a return to limited practices this week, the veteran wideout has a chance to return to action versus New York. Even though he didn't practice fully Wednesday through Friday, Parker could get the green light to play Sunday if he gains clearance from an independent neurologist at some point Saturday. In the seven outings he's played in this season, Parker has notched 15 catches for 158 yards and no touchdowns on 25 targets, a level of production that has thus far limited his fantasy lineup utility to deeper formats.
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Zay Jones WR | ARI
Jaguars' Zay Jones: Questionable after limited practice
Jones (knee) is listed as questionable for Sunday's game against the Texans.
Jones put forth a third consecutive limited practice Friday, per Adam Caplan of SiriusXM NFL Radio. He returned from a five-game absence in Week 11 against Tennessee and played 63 percent of offensive snaps in the 34-14 win. Jones has caught 12 of 22 targets for 98 yards and two touchdowns in four appearances this season, and he'll hope to get a chance to add to those totals Sunday.
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Noah Brown WR | LV
Texans' Noah Brown: Ruled out this week
Brown (knee) has been ruled out for Sunday's game against the Jaguars.
Brown, who wasn't able to practice this week, will thus target a potential return to action Dec. 3 against the Broncos. In his continued absence this weekend, Nico Collins, Tank Dell and Robert Woods are slated to headline the Texans' wideout corps.
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A.J. Brown WR | NE
Eagles' A.J. Brown: Cleared for Week 12
Brown (thigh) doesn't have an injury designation for Sunday's game against the Bills.
Brown upgraded to full participation Friday after being listed as limited the previous two days. He's coming off his first dud of the season -- one catch for eight yards in Monday's win over Kansas City -- but is already over 1,000 receiving yards for the campaign.
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Derek Wright WR | CAR
Derek Wright: Going on practice squad IR
The Panthers placed Wright on the practice squad injured list Friday with a knee injury, Mike Kaye of The Charlotte Observer reports.
Wright suffered the injury in practice Thursday. The 25-year-old wide receiver has yet to make his NFL debut and won't be eligible for elevation to the 53-man roster for any of the Panthers' next four games.
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Darius Slayton WR | IND
Giants' Darius Slayton: Listed as doubtful
Slayton (neck) is listed as doubtful for Sunday's game against the Patriots, Art Stapleton of The Bergen Record reports.
Slayton returned to practice Thursday after an early exit from Sunday's win over Washington, but it appears he isn't quite healthy enough to play. His likely absence could free up snaps for a number of different wide receivers, including Sterling Shepard, Isaiah Hodgins and Jalin Hyatt. The Giants have a Week 13 bye after Sunday's matchup with New England.