Knight (ankle) rushed five times for 24 yards and a touchdown while adding four receptions for 21 yards in Sunday's 41-22 loss to the 49ers.

Knight was a limited participant in practice all week with a bum ankle, but he was able to suit up Sunday and finish as the Cardinals' leading rusher. The 24-year-old outproduced Emari Demercado (5-8-0), who sustained an ankle injury during the contest, which is the inverse of how the backfield mates had performed in recent weeks. Michael Carter remained involved with 28 combined yards on seven touches, making this a truly frustrating committee to predict on a weekly basis. The fact that Knight started and scored Arizona's only rushing score of the contest makes him the preferred fantasy option by default heading into next Sunday's tilt against Jacksonville.

Hunt carried the ball 13 times for 59 yards and a touchdown and caught one of two targets for three yards in Sunday's 22-19 loss to the Broncos.

The veteran running back got into the end zone for a third straight game when he punched home a two-yard TD in the third quarter. Hunt's 62 scrimmage yards were also a season high, as he continues to need those touchdowns to keep his fantasy relevance. Through 10 games, he's produced just 419 scrimmage yards but has seven totals TDs -- six on the ground and one through the air. Hunt will look to hit paydirt again in Week 12 against the Colts.

Singletary rushed 16 times for 44 yards and two touchdowns and brought in his only target for three yards in the Giants' 27-20 loss to the Packers on Sunday.

Singletary wasn't efficient on the ground, but he made up for the modest yardage with five- and two-yard touchdown runs in the first half. The veteran back logged just three fewer carries than Tyrone Tracy, but the latter managed to double up Singletary in rushing yardage and also contributed 51 receiving yards. Consequently, Singletary projects to continue serving in a No. 2 role during a Week 12 road matchup against the Lions.

Tracy rushed 19 times for 88 yards and brought in all four targets for 51 yards in the Giants' 27-20 loss to the Packers on Sunday.

Tracy was given the chance to pace the ground attack in interim head coach Mike Kafka's first game at the helm, and the second-year pro responded with his best all-around performance of the campaign. With Sunday's performance, Tracy eclipsed what was then a season-high 71 rushing yards he'd posted in Week 10 against the Bears, and he also finished with a season high in receiving yards. Given Sunday's results, Tracy figures to remain in the top role during a Week 12 road matchup against the Lions despite the fact backfield mate Devin Singletary was also effective with two rushing touchdowns on 16 carries.

Spears logged four carries for three yards and caught all five of his targets for 31 yards in Sunday's 16-13 loss to the Texans.

Spears was unable to get anything going on the ground, posting a season-low three rushing yards. The running back was able to set a new season high in receptions, though, leading the team in that category. Spears remains limited by the Titans' overall lack of upside offensively, but he has now secured at least three catches in five straight games.

Vidal rushed five times for 13 yards and brought in both targets for minus-1 yard in the Chargers' 35-6 loss to the Jaguars on Sunday.

Vidal was stonewalled on his few opportunities, and a game script that saw the Jaguars eventually pull away from the Chargers essentially put a quick end to any fantasy hopes the running back and his fantasy managers had. Vidal also battled through a thigh injury that led to a brief exit from the game, and he ultimately finished with his lowest rushing yardage total in any game during which he's logged any carries this season. Sunday may have been Vidal's final game in the lead-back role as well, as Omarion Hampton (IR, ankle) may be ready to return for a Week 13 home matchup against the Raiders on Sunday, Nov. 30 following the Week 12 bye.

Corum rushed eight times for 10 yards and caught one of two targets for minus-5 yards in Sunday's 21-19 win over the Seahawks.

Corum has recorded at least nine touches in each of the past four games, but he isn't a threat to Kyren Williams' spot atop the running back depth chart. Williams mustered 96 scrimmage yards and a touchdown on 12 carries and two targets Sunday. Corum will likely continue to fill a change-of-pace role in Week 12 against the Buccaneers.

Williams rushed 12 times for 91 yards and a touchdown while catching one of two targets for five yards in Sunday's 21-19 win over the Seahawks.

Most of Williams' production came in the first quarter, as he had a two-yard rushing touchdown sandwiched between runs of 30 and 34 yards. He was significantly more effective on a per-touch basis than Blake Corum, who turned nine touches into just five scrimmage yards. Corum has siphoned off 11.5 carries per game in the last four, but Williams remains the lead back in an excellent Rams offense, keeping Williams' fantasy value high heading into a Week 12 home game against the Buccaneers.

Saylors (back) is active for Sunday night's matchup with the Eagles.

Saylors will make his return to action after missing the team's win over Washington in Week 10 due to a back injury. The running back likely will be plugged back in as the Lions' primary kickoff returner against Philadelphia.

Vaki (ankle) is active for Sunday night's contest against Philadelphia.

Vaki is good to go after working through an ankle injury during the week at practice. With Craig Reynolds (coach's decision) inactive, Vaki will operate as the No. 3 option at running back behind Jahmyr Gibbs and David Montgomery in Week 11.