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Gus Edwards RB | LAC
Ravens' Gus Edwards: Combines to go over 100 again
Edwards rushed 14 times for 92 yards and added 13 receiving yards by catching his lone target in Saturday's 22-10 win over the Chargers.
Edwards continues to thrive as the lead back under Lamar Jackson's iteration of the Ravens' offense. The threat of a mobile quarterback has opened up running lanes and allowed the undrafted rookie to produce at least 100 all-purpose yards in four out of the last six contests. Edwards is a non-factor in the passing game (Saturday's catch was his first since becoming starter), but his healthy production on the ground combined with a consistent role makes him start-worthy in almost any format. The Browns and their 24th-ranked rush defense are on tap for Week 17.
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Melvin Gordon RB | BAL
Chargers' Melvin Gordon: Touchdown salvages uneven outing
Gordon (knee) carried the ball 12 times for 41 yards and a touchdown, while also catching all three of his targets for 13 yards in the 22-10 loss to the Ravens on Saturday.
Gordon benefited from a Ravens fumble to begin the third quarter, taking advantage of nice field position to score his first touchdown following a three-game absence. That was about it in the form of pleasantries, as Gordon and the rest of the Chargers offense simply failed to generate any sort of yardage against a swarming Ravens defense. Perhaps more alarming, Gordon was often subbed out in passing situations, in part due to an unusually bad performance in terms of pass protection, where he yielded snaps and targets to Justin Jackson, who finished with seven catches for 47 yards. There's a real possibility the Chargers will already know their playoff fate prior to their next scheduled contest, as the Chiefs will play two games (one Sunday night against the Seahawks and Week 17 at 1:00 p.m. EST against the Raiders) before the Chargers take on the Broncos at 4:25 p.m. EST next week. Barring any sort of "schedule flexing" shenanigans, should the Chiefs win both of those contests, Gordon along with a number of other key skill position players could run the risk of taking a seat for precautionary reasons with the No. 5 seed already set in stone.
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Derrick Henry RB | BAL
Titans' Derrick Henry: Hits paydirt in victory
Henry rushed 21 times for 84 yards and a touchdown in Saturday's 25-16 win over Washington. He caught his lone target for eight yards.
Henry also missed his first pass attempt of the season, ending his hopes of a perfect completion percentage for the year. (He's 2-of-3 for 14 yards.) All joking aside, the bruising back turned in another fine fantasy performance, even if it wasn't as impressive as the two monster games he was coming off. The 24-year-old is finally looking like the top-end fantasy back that many hoped he would become during drafts. It only took the Titans' coaching staff 13 weeks to finally feature him, but better late than never. Henry should be in store for another 20-plus touch workload in an important matchup with the Colts in Week 17.
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Samaje Perine RB | CIN
Redskins' Samaje Perine: Healthy inactive
Perine (coach's decision) won't play in Saturday's game versus the Titans.
Saturday's designation means Perine will miss his sixth straight game and fourth as a healthy inactive. Adrian Peterson, Chris Thompson and Byron Marshall will continue to field the touches out of the backfield.
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Rashaad Penny RB | CAR
Seahawks' Rashaad Penny: Looking unlikely for Sunday
Coach Pete Carroll didn't sound optimistic about Penny (knee) being able to play Sunday against the Chiefs, Brady Henderson of ESPN.com reports. "We're holding out hope that maybe on gameday [Penny] can do something," Carroll said Friday. "We'll find out. He did a little bit of work [Friday] for the first time this week and his recovery is going really well."
Although he referred to Penny as a game-day decision, Carroll doesn't seem to have any expectation that the rookie will be able to play. Penny returned to practice Friday as a limited participant, logging his first activity of any kind since Week 14. An absence Sunday would free up a few extra touches for Mike Davis and Chris Carson, with J.D. McKissic potentially getting the occasional snap.
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Rashaad Penny RB | CAR
Seahawks' Rashaad Penny: Headed for game-day call
Penny is viewed as a game-day decision for Sunday's matchup with the Chiefs, John Boyle of the Seahawks' official site reports.
Per Boyle, Penny is listed as questionable on the Seahawks' final injury report after returning to practice Friday as a limited participant. His availability shouldn't have a huge impact on the Seahawks' game plan, as they can simply allow Chris Carson and/or Mike Davis to take a few more carries if the rookie isn't available. Davis handled the vacated snaps in last week's 26-23 loss to the 49ers, but Carson might be the beneficiary if Seattle were to play with a lead this time around.
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Zach Zenner RB | NO
Lions' Zach Zenner: Primed for more work if Blount sits
With Kerryon Johnson (knee) on injured reserve and LeGarrette Blount (calf) listed as questionable, Zenner and Theo Riddick are the Lions' only healthy running backs heading into Sunday's game against Minnesota, Kyle Meinke of MLive.com reports.
Zenner already appeared to usurp Blount for the lead role during last week's 14-13 loss at Buffalo, getting the start and posting a 10-45-1 rushing line while the 32-year-old produced just nine yards on seven carries. Of course, Riddick contributed 47 yards on eight carries and nine yards on two receptions, so a timeshare will likely still be in the works even if Blount doesn't play Sunday. The prospect of sharing with one player instead of two obviously boosts Zenner's fantasy outlook, but there's no guarantee it comes to fruition and also no guarantee the injury-riddled Lions have any success against a tough Minnesota defense.
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Damien Williams RB | ARI
Chiefs' Damien Williams: Primed for another big workload
Williams is positioned for a sizable workload Sunday against the Seahawks with teammate Spencer Ware (hamstring) listed as doubtful for the contest, Field Yates of ESPN reports.
Williams took full advantage of the same situation in last week's 29-28 loss to the Chargers, piling up 123 scrimmage yards and two scores on 16 touches while handling a 73 percent snap share. He'll now take aim at a defense that has allowed running backs to produce 4.6 yards per carry and 7.4 per target, though Seattle did a much better job containing opposing backfields the past three weeks (zero touchdowns, 222 rushing yards). Williams' career mark of 3.6 YPC isn't encouraging, but there's a lot to be said for handling the lead back role in an offense led by Andy Reid and Patrick Mahomes.
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John Kelly RB | CLE
Rams' John Kelly: May trail Anderson in pecking order
Kelly is expected to work as the backup to C.J. Anderson in the event Todd Gurley (knee) and Justin Davis (shoulder) are unavailable for Sunday's game against the Cardinals, Lindsey Thiry of ESPN.com reports.
Kelly, a sixth-round pick out of Tennessee, exhibited some explosiveness during his opportunities in the preseason, but he's largely been an afterthought for the Rams since the regular season began. In fact, Kelly didn't dress for a game until Week 14, when Malcolm Brown's season-ending collarbone injury bumped him up a spot on the depth chart. It appeared the door might have open for Kelly to claim a three-down role when Gurley and Davis both came out of the Week 15 loss to the Eagles with injuries, but the recent addition of Anderson has put somewhat of a damper on the rookie's prospects. Instead, Kelly now looks like a better bet to serve as a change-of-pace option if Gurley and Davis are sidelined, taking on the bulk of the snaps on passing downs while the more experienced Anderson works as the primary ballcarrier. Regardless of how the Rams' running-back situation plays out in Week 16, there probably won't be much clarity until the team releases its inactive list 90 minutes prior the 4:05 p.m. EST kickoff.