NFL Player News

Breida (ankle) wasn't on the field for Thursday's practice, Matt Barrows of The Athletic reports.

Ian Rapoport of NFL Network reported that Breida would likely be sidelined for 1-to-2 weeks after aggravating a low-ankle sprain in Monday's loss to the Seahawks, so it shouldn't come as much of a surprise that he's been withheld from both of the 49ers' first two practices of Week 11. With Breida trending toward an inactive status this weekend versus Arizona, Tevin Coleman -- who was also absent from Thursday's practice due to a non-injury-related matter -- is expected to take on a more pronounced role in the San Francisco backfield.

Wilkins (ankle) was not spotted at the portion of Thursday's practice open to the media, Kevin Bowen of 107.5 The Fan Indianapolis reports.

Wilkins appears on track for a "DNP" designation on Thursday's practice report, putting his chances of suiting up versus the Jaguars on Sunday in legitimate jeopardy. He hasn't practiced in any capacity since suffering an ankle injury Week 10 versus the Dolphins. Jonathan Williams would slot in as Indianapolis' No. 3 running back if Wilkins were forced to miss any time.

McCaffrey (foot) practiced fully Thursday, Brendan Marks of The Charlotte Observer reports.

McCaffrey has had limitations on his practice reps for three consecutive weeks at this point, but they were lifted on each occasion. As a result, his foot issue won't impact his availability for the Panthers' Week 11 divisional matchup with the Falcons, who have conceded 124.9 yards from scrimmage per game and nine touchdowns to running backs in nine contests this season.

Coach Matt Nagy said that Montgomery "lightly" rolled an ankle during Wednesday's practice, leaving the running back's availability uncertain for this weekend's game against the Rams, Rich Campbell of the Chicago Tribune reports.

Nagy's comments provide an explanation for why Montgomery was surprisingly listed as a limited participant Wednesday in the Bears' first practice of the week. It's uncertain whether the rookie will be able to resume practicing Thursday and/or Friday, but his ability to bounce back from the ankle sprain over the next couple of days will likely have significant sway on his status for the weekend. If Montgomery -- who has played at least 60 percent of the offensive snaps in each of the last three weeks while garnering 17-plus touches on every occasion -- is limited or sidelined against the Rams, Tarik Cohen and Ryan Nall would be in store for heightened roles in the team's backfield.

Mostert (knee) was a limited participant at Wednesday's practice.

Mostert has been playing through the knee injury for about a month, so it's no real surprise to see him on the injury report again this week. The 27-year-old's ability to practice to start the week puts him on track to once again play through the injury Sunday against the Cardinals.

Edmonds (hamstring) was a non-participant at Wednesday's practice, Josh Weinfuss of ESPN.com reports.

Edmonds has made negligible progress in his recovery from a hamstring injury, missing every practice and two games since picking up the issue Week 8. With Kenyan Drake and David Johnson in their backfield, the Cardinals don't need to rush Edmonds through his rehab. Plus, the team has a bye after Sunday's game at Arizona, so it wouldn't surprise if Edmonds misses a third consecutive contest this weekend.

Breida (ankle) didn't practice Wednesday, Cam Inman of The San Jose Mercury News reports.

Breida is expected to miss 1-to-2 weeks as a result of a low-ankle sprain, so his listing on Wednesday's injury report isn't a surprise. If he indeed takes a seat Sunday versus the Cardinals, the 49ers backfield will be down to Tevin Coleman, Raheem Mostert and Jeff Wilson.

Jacobs (shoulder) was listed as a limited practice participant Wednesday, Paul Gutierrez of ESPN.com reports.

Jacobs managed a shoulder issue leading up to last Thursday's 26-24 win over the Chargers before logging 30 of a possible 58 snaps on offense, en route to carrying 16 times for 71 yards and a TD and catching three passes for 30 yards. With no reported setbacks in that contest, we'll presume for now that Jacobs' limitations Wednesday were maintenance-related.

Wilkins (ankle) did not practice Wednesday.

Wilkins was forced out of Sunday's loss to the Dolphins in the third quarter due to an ankle issue. He'll have two more opportunities to participate in practice ahead of Sunday's game against the Jaguars. In the event Wilkins was forced to miss any time, Nyheim Hines and Jonathan Williams would be candidates to see increased roles behind No. 1 running back Marlon Mack.

Montgomery was limited at Wednesday's practice due to an ankle injury.

Since seeing a season-low four touches Week 7 against the Saints, Montgomery has bounced back over the last three games, racking up 65 touches for 283 yards and three touchdowns. With the lead role locked down ahead of change-of-pace back Tarik Cohen, Montgomery has become the most consistent option in the Bears offense, but the aforementioned health concern could throw a wrench into that development.