The Cowboys placed Mafah (shoulder) on injured reserve Wednesday.

Mafah suffered a shoulder injury during the preseason finale and will now be sidelined for a minimum of the first four games of the regular season. He'll likely be buried on the depth chart when he returns, but the Cowboys' running back situation is quite uncertain entering the season.

The Chargers signed Hines to their practice squad Wednesday.

Just a day after being waived by the Chargers, Hines is already back with the club on their practice squad. His last regular-season action came back in 2022, when he turned 54 touches into 274 scrimmage yards over 16 games with the Bills and the Colts.

Tyus signed with the Seahawks' practice squad Wednesday.

Tyus will join fellow rookie running backs Damien Martinez (seventh round) and Jacardia Wright (undrafted) on the Seahawks' practice squad. Tyus finished the preseason with just 21 carries for 55 yards (2.6 YPC) and one catch for two yards. He's a long shot to get called up to the active roster.

Martinez signed with the Seahawks' practice squad Wednesday.

Martinez was highly touted even as a seventh-round pick due to a productive collegiate career at where he rushed for 2,187 yards (6.2 YPC) and 19 touchdowns over his final two seasons. However, the Miami product had an underwhelming preseason with just 84 yards on 24 carries (3.5 YPC) and was clearly outplayed by second-year back George Holani, who earned a spot on the active roster. Martinez is still just 21 years old and will have time to develop in a system that's favorable to running backs. If one of Holani, Kenneth Walker or Zach Charbonnet gets injured, either Martinez or Jacardia Wright will likely be called up.

Saylors signed with the Lions' practice squad Wednesday.

Saylors is entering his third season in the NFL but has yet to play in a regular-season game. He was highly productive over his past two seasons at East Tennessee State, but he'll need injuries to pile up before he gets a shot on the active roster.

Herbert signed to the Colts' practice squad Wednesday.

The running back was released Tuesday after falling short of the team's 53-man roster, and while, given his experience in the league, he may have been expected to end up with another team, Herbert cleared waivers and remained with Indy. The former Bengal and Bear initially signed with the Colts in March after appearing in 14 regular-season games for the aforementioned teams in 2024, but he failed to make the roster after missing the last two preseason games with an undisclosed injury. Healthy now, Herbert is perhaps a candidate for a call-up if the Colts need running back help behind Jonathan Taylor during the regular season.

Bentley signed to the Colts' practice squad Wednesday.

The running back was waived Tuesday after failing to make the 53-man roster, but he was able to return to Indianapolis after clearing waivers. In the preseason, Bentley recorded 22 carries for 94 yards and two scores as well as two catches for 13 yards. The Colts' running back room is led by Jonathan Taylor, though it is thin behind him.

Jennings was signed to the Patriots' practice squad Wednesday.

Jennings went unclaimed on waivers after being cut loose by the team Tuesday, and he will now stick around New England as a member of the practice unit. The running back played in three regular-season contests with the Patriots in 2024, so he's certainly familiar with the organization.

The Ravens signed Johnson to the practice squad Wednesday, Ryan Mink of the team's official site reports.

Johnson joined the Ravens in early August with the aim of cracking to make the 53-man roster, but he failed to beat out Rasheen Ali for the RB4 spot. Johnson will return to the Ravens on the practice squad and is a candidate to be elevated to the active roster if Ali, Keaton Mitchell, Justice Hill or Derrick Henry were unable to play. Johnson logged 46 carries for 163 yards and two touchdowns while adding five catches (on eight targets) for 26 yards across the Ravens' three preseason games.

James (finger) returned to practice Wednesday, Nick Wagoner of ESPN.com reports.

James missed some time early in training camp due to a knee injury and then broke a finger not long afterward that required surgery, resulting in him missing the 49ers' entire preseason slate. Despite the time away from the field, the rookie fifth-round pick survived roster cuts and resides in a backfield led by Christian McCaffrey and followed by newcomer Brian Robinson and second-year pro Isaac Guerendo. As a result, James may be a regular inactive on game days, even when he's healthy enough to be available.